

Maintenance of Calcified Tissues
Bone
remodeling continues throughout life, but around age 40 osteoclastic activity
begins to exceed osteoblastic activity with a net loss of bone on the average of
1.2% per year.18 The nutrients
known to affect bone formation include vitamin A, C, D, K, zinc, magnesium,
phosphorus and calcium.19
Vitamin D regulates the absorption of calcium from the gastrointestinal tract to maintain calcium balance. When calcium intake is inadequate, vitamin D stimulates osteoclasts to help mobilize the calcium stored in bone. Both collagen synthesis and accumulation of mineralized bone are dependent on adequate levels of vitamin D and calcium.7
A nutrient seldom discussed in terms of bone health is vitamin K. There is, however, an association between vitamin K insufficiency and reductions in bone density and possibly bone strength.20 This may be of particular concern among people taking vitamin K antagonists such as oral anticoagulants as a significant decrease in bone mineral density has been observed.20
Minerals
involved in the calcified tissues include boron, calcium, copper,
and magnesium. A recent epidemiologic study using the NHANES
III data found the risk of periodontal disease was 56% greater in
women with dietary intakes of calcium below 500 mg/day and 27%
greater for those taking in less than 800 mg/day.21 The study goes on to
suggest that low dietary calcium intake results in more severe
periodontal disease. However, it remains unclear how calcium
supplementation might impact the course of periodontal disease.21 Furthermore, evidence is
accumulating that indicates a correlation between systemic
osteoporosis, alveolar bone, and ultimately tooth loss in
post-menopausal women.22-25 |