This randomized and controlled, examiner-blind, 3-period, crossover clinical trial was designed to determine the effect of an experimental denture adhesive, a marketed denture adhesive (European Fixodent® Fresh), or no denture adhesive on the breath odor of 37 adults wearing full maxillary and mandibular dentures.  Breath quality was measured at baseline and at 3 and 6 hours after the start of each treatment period via monitoring of volatile sulfur compounds (VSCs) using a halimeter and second-person organoleptic grading.  A 48-hour washout phase separated treatment periods.  There were no statistically significant differences in VSCs between any of the treatment regimens over 6 hours.  Both the denture adhesive treatments were superior in breath quality improvement in organoleptic scores compared to no denture adhesive at 3 and 6 hours (p=0.0001).  This research demonstrates the ability of both an experimental and marketed denture adhesive to deliver superior second-person breath benefits relative to no adhesive.  The results indicate that Fixodent® denture adhesives provide the denture wearer with a noticeable improvement in breath.

Keywords:  Denture adhesive, clinical trial, breath malodor

Citation:  Myatt GJ, Hunt SA, Barlow AP, et. al.  A Clinical Study to Assess the Breath Protection Efficacy of Denture Adhesive.  J Contemp Dent Pract 2002 November;(3)4:001-009.