Introduction

Central giant cell granuloma (CGCG) is an uncommon, benign, and proliferative lesion whose etiology is not defined.^1,2  It was Jaffe who first introduced the term central giant cell reparative granuloma to distinguish this lesion from the giant cell tumor of long bones.  However, since a reparative response was quite rare and most of these lesions were found out to be destructive rather than reparative, the word ‘reparative’ was omitted from that term.^3,4

Though CGCG may be seen in every age group, it is much more common in the young, especially those under 30 years of age.^1-7  An asymptomatic lesion on the whole, CGCG may lead to an expansion in the cortex so long as it grows up.⁷  It has been reported the enlarged size of the lesion has caused tooth mobility, tooth displacement, and root resorption.^1,3,5,6  The borders of the lesions may be regular or diffuse.^3,7

Since CGCG possesses such different features, some researchers^4,8-10 have defined the lesion into two types, referring to its clinical and radiographic features.  The first type of lesion is non-aggressive, grows slowly, does not show root perforation in teeth affected by the lesion or cortical perforation, and often shows new bone formation; the other lesion is the aggressive type that grows quickly, shows pain, cortical perforation, and root resorption.

On the other hand, although the clinical, radiologic, and histologic features of CGCG have been extensively evaluated, the dimensional features of these lesions have not been clearly defined.  The purpose of this study is to present the dimensional features as well as the clinical and radiological features of 27 CGCG cases.

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Citation Number: Vol. 4, No. 3, Page 088