The Journal of Contemporary Dental Practice

Register      Login

SEARCH WITHIN CONTENT

FIND ARTICLE

Volume / Issue

Online First

Archive
Related articles

VOLUME 11 , ISSUE 1 ( January, 2010 ) > List of Articles

RESEARCH ARTICLE

Limited Benefit of Copaifera Oil on Gingivitis Progression in Humans

Sérgio Luís da Silva Pereira, Cristiane Simões Barros, Thiago Daher Yunes Salgado, Vicente Paulo Pereira Filho, Flávio Nogueira Costa

Citation Information : da Silva Pereira SL, Barros CS, Salgado TD, Filho VP, Costa FN. Limited Benefit of Copaifera Oil on Gingivitis Progression in Humans. J Contemp Dent Pract 2010; 11 (1):57-64.

DOI: 10.5005/jcdp-11-1-57

License: CC BY-NC 3.0

Published Online: 01-01-2010

Copyright Statement:  Copyright © 2010; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Aim

The aim of this in vivo study was to evaluate the antiplaque and antigingivitis effect of Copaifera sp (Cp).

Methods and Materials

Twenty-three subjects participated in a randomized controlled clinical trial using a 21-day, partial-mouth experimental model of gingivitis. A custom tooth shield was fabricated for each subject to prevent the brushing of the four experimental posterior teeth in the lower-left quadrant. The subjects were randomly assigned to either the control group (using a placebo gel) or the test group (using the test gel containing 10% Cp).

Results

The clinical results showed statistically significant differences for plaque (PLI), bleeding (BI), and gingival (GI) indexes at days 0 and 21 in both groups (p<0.05). However, on day 21 there was no statistically significant difference between groups for all indexes (p>0.05).

Conclusions

The test gel containing 10% Cp did not prevent plaque formation and development of gingivitis.

Clinical Significance

Several medicinal herbs are used empirically by persons in the treatment and prevention of oral conditions. Research in this area must be encouraged to determine which herbal agents would be a useful addition to the current range of chemotherapeutic periodontal treatment options.

Citation

Pereira SLS, Barros CS, Salgado THY, Filho VPP, Costa FN. Limited Benefit of Copaifera Oil on Gingivitis Progression in Humans. J Contemp Dent Pract [Internet]. 2010 Jan; 11(1):057-064. Available from: http://www.thejcdp. com/journal/view/volume11-issue1-pereira.


PDF Share
  1. Trends over 30 years, 1973–2003, in the prevalence and severity of periodontal disease. J Clin Periodontol. 2008; 35(5):405-14.
  2. On the prevention of caries and periodontal disease. Results of a 15-year longitudinal study in adults. J Clin Periodontol. 1991; 18(3):182-9.
  3. Experimental gingivitis in man. J Periodontol. 1965;36: 177-87.
  4. Effect of 3 dentifrices containing triclosan and various additives. An experimental gingivitis study. J Clin Periodontol. 2000; 27(7):494-8.
  5. A study to assess the plaque inhibitory action of a newly formulated triclosan toothpaste. J Clin Periodontol. 2001; 28(1):86-9.
  6. The effect of three commercially available dentifrices containing triclosan on supragingival plaque formation and gingivitis: a six month clinical study. Int Dent J. 1994; 44(1 Suppl 1):75-81.
  7. A 6-month home usage trial of a 1% chlorhexidine toothpaste (1). Effects on plaque, gingivitis, calculus and toothstaining. J Clin Periodontol. 1993; 20(2):130-8.
  8. The antimicrobial potential of 14 natural herbal dentifrices: results of an in vitro diffusion method study. J Am Dent Assoc. 2004; 135(8):1133-41.
  9. Antiplaque and antigingivitis effects of a gel containing Punica granatum Linn extract: a double-blind clinical study in humans. J Appl Oral Sci. 2006; 14(3):162-6.
  10. Sangtherapitikul P, Grimm WD. Adjunctive periodontal treatment with Centella asiatica and Punica granatum extracts in supportive periodontal therapy. J Int Acad Periodontol. 2005;7(3):70-9.
  11. Antimicrobial activity of the essential oil from Lippia sidoides, carvacrol and thymol against oral pathogens. Braz J Med Biol Res. 2007; 40(3):349-56.
  12. Terpenoids from Copaifera cearensis. Phytochemistry 1998; 49:263-4.
  13. Antiinflammatory activity of copaiba balsam (Copaifera cearensis Huber). Rev Bras Farm 1992; 73:53-6.
  14. Análise comparativa entre o óleo-resina de copaíba e o digluconato de clorexidina no processo de cicatrização tecidual. Estudo histológico em dorso de ratos. [Comparative evaluation between copaiba oil-resin and chlorhexidine digluconate on wound healing. Histological study in rats.] Rev Odontol Unesp. 2005; 34(2):107-12.
  15. Anti-inflammatory activity of oleoresin from Brazilian Copaifera. J Ethnopharmacol. 1988;22(1):101-9.
  16. Investigation on the wound healing activity of oleo-resin from Copaifera langsdorffi in rats. Phytother Res. 2002; 16(8):737-9.
  17. Phytochemical and antioedematogenic studies of commercial copaiba oils available in Brazil. Phytother Res. 2001;15(6):476-80.
  18. The experimental gingivitis studies: the microbiological perspective. J Dent Res. 1996; 75(7):1634-8.
  19. Reduced plaque formation by the chloromethyl analogue of victamine C. J Periodontol. 1970; 41(1):41-3.
  20. Periodontal disease in pregnancy. I. Prevalence and severity. Acta Odontol Scand. 1963; 21:533-51.
  21. Problems and proposals for recording gingivitis and plaque. Int Dent J. 1975; 25(4):229-35.
  22. Ethnomedicine of Dharwad district in Karnataka, India—plants used in oral health care. J Ethnopharmacol. 2004; 94(2-3):261-6.
  23. Evaluation of antiplaque activity of Azadirachta indica leaf extract gel—a 6-week clinical study. J Ethnopharmacol. 2004; 90(1):99-103.
  24. Effect of a novel essential oil mouthrinse without alcohol on gingivitis: a double-blinded randomized controlled trial. J Appl Oral Sci. 2007; 15(3):175-80.
  25. Estudo comparativo in vitro da atividade antibacteriana de produtos fitoterápicos sobre bactérias cariogênicas. [Comparative study in vitro of the antibacterial activity from phytotherapeutic products against cariogenic bacterias.] Pesqui Bras Odontoped Clin Integr. 2004; 4(1):33-8.
  26. Evaluation of the safety and efficacy of over-the-counter oral hygiene products for the reduction and control of plaque and gingivitis. Periodontol 2000. 2002; 28:91-105.
  27. The effects of a tea tree oil-containing gel on plaque and chronic gingivitis. Aust Dent J. 2004; 49(2):78-83.
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.