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VOLUME 12 , ISSUE 2 ( March-April, 2011 ) > List of Articles


Retrospective Study of 25 Cases of Keratocystic Odontogenic Tumor: Epidemiology and Treatment

Juliana L Schussel, Roberta T Stramandinoli, Jose Luis Dissenha, Lucia FC Avila, Laurindo M Sassi

Citation Information : Schussel JL, Stramandinoli RT, Dissenha JL, Avila LF, Sassi LM. Retrospective Study of 25 Cases of Keratocystic Odontogenic Tumor: Epidemiology and Treatment. J Contemp Dent Pract 2011; 12 (2):100-103.

DOI: 10.5005/jp-journals-10024-1016

Published Online: 01-12-2011

Copyright Statement:  Copyright © 2011; The Author(s).



Keratocystic odontogenic tumor (KOT) is a benign odontogenic neoplasm with locally aggressive behavior and high recurrence rates. It is associated with nevoid basal cell carcinoma syndrome which usually has a more rapid growth. The aim of the study is to report the experience of our service on diagnosis and treatment of KOT.

Materials and methods

Twenty-five cases of KOT were diagnosed between the years of 1989 and 2006. Demographic data was collected as well as diagnose and treatment.


Fifty-six percent were female with a mean age of 33 years old. Seventy percent occurred in mandibula and all received surgical treatment, associate or not with adjuvant therapy, such as cryotherapy and Carnoy's solution. Recidive was observed in 48% of cases with a mean period of time of 18 months.


Our data analysis showed the importance of previous diagnosis before enucleation procedure and long-term follow-up for recurrence early detection. Recurrence incidence is more frequent on first year after diagnosis.

Clinical significance

KOT is a benign tumor with local aggressive behavior and therefore its treatment must consider the high index of recidive. Reports of protocol treatment should raise new discussion to decrease recurrence rates.

How to cite this article

Schussel JL, Stramandinoli RT, Dissenha JL, Avila LFC, Sassi LM. Retrospective Study of 25 Cases of Keratocystic Odontogenic Tumor: Epidemiology and Treatment. J Contemp Dent Pract 2011;12(2):100-103.

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