Clinical Effect of a Mouth Rinse containing Ocimum gratissimum on Plaque and Gingivitis Control
Sérgio Luís da Silva Pereira, José Weslley Gonçalves de Oliveira, Keyles Karla Sá Vieira Ângelo, Ângela Maria Alves da Costa, Flávio Costa
Citation Information :
da Silva Pereira SL, de Oliveira JW, Ângelo KK, da Costa ÂM, Costa F. Clinical Effect of a Mouth Rinse containing Ocimum gratissimum on Plaque and Gingivitis Control. J Contemp Dent Pract 2011; 12 (5):350-355.
Copyright © 2011; Jaypee Brothers Medical Publishers (P) Ltd.
The effect of Ocimum gratissimum (Og) on the reduction of dental plaque and gingivitis was evaluated in a randomized, parallel and double-blind clinical trial.
There was a significant reduction on plaque and gingivitis in tests groups (p < 0.05), but no statistically significant difference was observed among them (p > 0.05).
Mouth rinse containing Og was effective as antiplaque and antigingivitis agent, in a similar manner that chlorhexidine digluconate.
Research in treatment of chronic oral diseases using natural agents must be encouraged to verify which would be a useful addition to the current range of chemotherapeutic treatment options.
How to cite this article
da Silva Pereira SL, de Oliveira JWG Ângelo KKSV, da Costa ÂMA, Costa F. Clinical Effect of a Mouth Rinse containing Ocimum gratissimum on Plaque and Gingivitis Control. J Contemp Dent Pract 2011;12(5):350-355.
Trends over 30 years, 1973- 2003, in the prevalence and severity of periodontal disease. J Clin Periodontol 2008;35:405-14.
Comparative analysis of the effect of two chlorhexidine mouth rinses on plaque accumulation and gingival bleeding. Braz Oral Res 2008;22:139-44.
On the prevention and caries and periodontal disease. Results of 15-year longitudinal study in adults. J Clin Periodontol 1991;18:182-89.
Experimental gingivitis in man. J Periodontol 1965;36:177-87.
Effect of 3 dentifrices containing triclosan and various additives. An experimental gingivitis study. J Clin Periodontol 2000;27:494-98.
A study to assess the plaque inhibitory action of a newly formulated triclosan toothpaste. J Clin Periodontol 2001;28:86-89.
The effect of three commercially available dentifrices containing triclosan on supragingival plaque formation and gingivitis: A six-month clinical study. Int Dent J 1994;44:75-81.
A 6-month usage trial of 1% chlorhexidine toothpaste. (1) Effects on plaque, gingivitis, calculus and toothstaining. J Clin Periodontol 1993;20:130-138.
Effect of different chlorhexidine formulations in mouthrinses on de novo plaque formation. J Clin Periodontol 2001;28:1127-36.
The antimicrobial potential of 14 natural herbal dentifrices: Results of an in vitro diffusion method study. J Am Dent Assoc 2004;135:1133-41.
Antiplaque and antigingivitis effects of a gel containing Punica Granatum Linn extract. A double-blind clinical study in humans. J Appl Oral Sci 2006;14:162-66.
Sangtherapl Itikul P, et al. Adjunctive periodontal treatment with Centella asiatica and Punica granatum extracts in supportive periodontal therapy. J Int Acad Periodontol 2005;7:70-79.
Antimicrobial activity of the essential oil from Lippia Sidoides, carvacrol and thymol against oral pathogens. Braz J Med Biol Res 2007;40:349-56.
Antiplaque and antigingivitis effect of Lippia Sidoides. A double-blind clinical study in humans. J Appl Oral Sci 2009;17:404-07.
Effect of a dentifrice containing aloe vera on plaque and gingivitis control. J Appl Oral Sci 2008;16:293-96.
Composition and antimicrobial actvity of essential oils from aromatic plants used in Brazil. Braz J Microbiol 2004;45:275-80.
Antifungal activity of essential oil isolated from Ocimum gratissimum L. (eugenol chemotype) against phytopathogenic fungi. Braz Arch Biol Tech 2006;49:867-71.
Justification for the use of Ocimum gratissimum L in herbal medicine and its interaction with disc antibiotics. BMC Compl Alternat Med 2009;9:1-6.
Antibacterial activity of Ocimum gratissimum L essential oil. Mem Inst Oswaldo Cruz 1999;94:675-78.
Antinociceptive and anti-inflammatory activities of aqueous leaves extract of Ocimum gratissimum (Labiate) in rodents. Afr J Trad CAM 2008;5:141-46.
Problems and proposals for recording gingivitis and plaque. Int Dent J 1975;25:229-35.
Reduced plaque formation by the chloromethyl analogue of victamine C. J Periodontol 1970;41:41-43.
Evaluación del efecto de un gel conteniendo extracto de aruera en el tratamiento de gingivitis. Estudio clínico em humanos. Acta Odontol Ven 2009;47:1-8.
The effectiveness and side effects of 0.1% and 0.2% chlorhexidine mouth rinses: A clinical study. Quintessence Int 1998;29:443-48.
A 0.05% cetyl pyridinium chloride/0.05% chlorhexidine mouth rinse during maintenance phase after initial periodontal therapy. J Clin Periodontol 2005;32:390-400.
Effects of supervised chlorhexidine mouthrinses in children. A longitudinal clinical trial. J Periodontal Res 1982;17:101-11.
A comparison of mouth rinses containing two concentrations of chlorhexidine. J Periodontal Res 1986;21: 23-32.
Limited benefit of Copaifera oil on gingivits progression in humans. J Contemp Dent Pract 2010;11:57-64.
Ethnomedicine of Dharwad district in Karnataka, India-plants used in oral health care. J Ethnopharmacol 2004;94:261-66.
Evaluation of antiplaque activity of Azadirachta indica leaf extract gel – a 6-week clinical study. J Ethnopharmacol 2004;90:99-103.
Antibacterial effects of the essential oils of commonly consumed medicinal herbs using an in vitro model. Molecules. 2010;27:15:7532-46.
In vitro antimicrobial activity of Ocimum americanum L. essential oil against oral microorganisms. Southeast Asian J Trop Med Public Health. 2009;40:1025-33.
Antifungal activities of Ocimum gratissimum towards dermatophytes. J Ethnopharmacol 2005;48:72-86.
Antifungal activities of Ocimum gratissimum towards Cryptococcus neoformans. J Ethnopharmacol 2005;20:4-13.
Antimicrobial activities of the volatile oils of Ocimum bacilicum L. and Ocimum gratissimum L. (Lamiaceae) against some aerobic dental isolates. Pak J Pharm Sci 2009;22:405-09.
Eugenol a valuable compound for in vitro experimental research and worthwhile for further in vivo investigation. Phytoth Res 1990;90-96.
Characterization of the action of selected essential oil components on Gram-negative bacteria. J Agric Food Chem 1998;46:3590-95.