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VOLUME 13 , ISSUE 4 ( July-August, 2012 ) > List of Articles


Microbial Colonization and their Relation with Potential Cofactors in Patients with Denture Stomatitis

Bhushan Arun Jawale, Rahul Redasani, Lalit Chaudhari, Narendra Chopde, Amol Pharande, Vardha Hiremath

Citation Information : Jawale BA, Redasani R, Chaudhari L, Chopde N, Pharande A, Hiremath V. Microbial Colonization and their Relation with Potential Cofactors in Patients with Denture Stomatitis. J Contemp Dent Pract 2012; 13 (4):456-459.

DOI: 10.5005/jp-journals-10024-1168

Published Online: 01-12-2012

Copyright Statement:  Copyright © 2012; The Author(s).



To determine microbial prevalence in the mucous membrane and prosthesis of denture wearers with and without denture stomatitis and to study its relationship with potential clinical cofactors.

Materials and methods

Saliva was collected from 200 patients (100 female and 100 male) wearing dental prosthesis for measurement of pH. Oral samples of the mucous membrane and of dentures were taken with sterile swab for microbiological analysis. Medical and dietary history of the subjects was recorded. Chi-square test and analysis of varience were used for statistical analysis.


Diabetes, hypertension and high carbohydrate ingestion was observed in majority of patients. The pH average in saliva was of 5.1. The presence of C. albicans, S. aureus and S. mutans in the mucous membrane was of 55.4, 56.4 and 63.6% respectively. C. albicans was isolated in 69.7% from the prosthesis, whereas S. aureus and S. mutans were isolated in 45.3%. The isolation of C.albicans was more frequent in patients with deture stomatitis.


C. albicans, S. aureus and S. mutans frequently colonize the oral mucous of denture wearers. This is more frequently observed in patients with denture stomatitis.

Clinical significance

Denture stomatitis is associated to Candida albicans, different bacteria and other cofactors, such as salivary pH, carbohydrate ingestion, systemic illnesses and medication.

How to cite this article

Chopde N, Jawale B, Pharande A, Chaudhari L, Hiremath V, Redasani R. Microbial Colonization and their Relation with Potential Cofactors in Patients with Denture Stomatitis. J Contemp Dent Pract 2012;13(4):456-459.

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