The Journal of Contemporary Dental Practice

Register      Login



Volume / Issue

Online First

Related articles

VOLUME 13 , ISSUE 6 ( November-December, 2012 ) > List of Articles


The Role of Plasma Female Sex Hormones on Gingivitis in Pregnancy: A Clinicobiochemical Study

Sandeep Prakash, Rashmita Nayak, Gopal Krishna Choudhury, Sumit Deshpande, KP Ashok, BR Spoorthi

Citation Information : Prakash S, Nayak R, Choudhury GK, Deshpande S, Ashok K, Spoorthi B. The Role of Plasma Female Sex Hormones on Gingivitis in Pregnancy: A Clinicobiochemical Study. J Contemp Dent Pract 2012; 13 (6):760-763.

DOI: 10.5005/jp-journals-10024-1225

Published Online: 01-12-2012

Copyright Statement:  Copyright © 2012; Jaypee Brothers Medical Publishers (P) Ltd.



To correlate the changes in the level of female sex hormones (progesterone, estrogen) in plasma with the changes in severity of gingivitis in various trimesters of pregnancy till the postparturition.

Materials and methods

This study comprised of 20 pregnant women with good oral hygiene who were followed up in each trimester till 3rd month of postpartum by screening their oral hygiene status following OHI-S index by Greene and Vermillion. Clinically to correlate gingivitis, gingival index by Loe and Sillness was carried out in each trimester till postpartum. For hormonal assay, blood sampling by venipuncture was done and quantative analysis of the hormones was done by ELISA test.

Results and conclusion

The severity of gingivitis gradually increased and reached its peak in 3rd trimester followed by sudden decline in the severity in postpartum which correlated with gradual increase in the plasma level of progesterone and estrogen levels to reach their peak in the 3rd trimester and sudden fall after the postpartum. This study shows the role of female sex hormones in aggravating gingivitis to its peak in the 3rd trimester, even though the oral hygiene remains fairly good constantly.

Clinical significance

This study signifies the gingivitis status during different trimesters of pregnancy and postpartum indicating the general practitioner to take appropriate oral hygiene measures.

How to cite this article

Nayak R, Choudhury GK, Prakash S, Deshpande S, Ashok KP, Spoorthi BR. The Role of Plasma Female Sex Hormones on Gingivitis in Pregnancy: A Clinicobiochemical Study. J Contemp Dent Pract 2012;13(6): 760-763.

PDF Share
  1. Periodontal changes in pregnancy. J Periodontol 1965;36:37/209-45.
  2. Influence of hormonal variation on the periodontium in women. Perio 2000;6:79-87.
  3. The effect of progesterone, estrogen and cortisol on gingival inflammation. JPR 1972;7:111-24.
  4. Plasma female sex hormone levels on gingivitis in pregnancy. J Periodontol 1979:50:4:279-82.
  5. Gingival condition of Egyptian pregnant women. J Periodontol 1970;41:271-72.
  6. A longitudinal investigation of the periodontal changes during pregnancy. J Periodontol 1969;40:563-70.
  7. Direct interaction of estradiol and progesterone with bacteriodes melaninogenicus. IADR abstracts 1979:58.
  8. Effects of topical and systemic folic acid supplementation on gingivitis in pregnancy. J Clin Period 1980;7:402-14.
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.