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VOLUME 14 , ISSUE 5 ( September-October, 2013 ) > List of Articles

RESEARCH ARTICLE

The Effects of Phase III Cardiac Rehabilitation in Serum and Salivary Hs-CRP and Anthropometric Measurements in Patients with Coronary Artery Disease

Iraj Mirzaii-Dizgah, Boshra Jamshidpour, Behrouz Attarbashi Moghadam, Behnoosh Vasaghi-Gharamaleki, Mostafa Nejatian

Citation Information : Mirzaii-Dizgah I, Jamshidpour B, Moghadam BA, Vasaghi-Gharamaleki B, Nejatian M. The Effects of Phase III Cardiac Rehabilitation in Serum and Salivary Hs-CRP and Anthropometric Measurements in Patients with Coronary Artery Disease. J Contemp Dent Pract 2013; 14 (5):819-824.

DOI: 10.5005/jp-journals-10024-1409

Published Online: 00-10-2013

Copyright Statement:  Copyright © 2013; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Aim

Cardiac rehabilitation is a key part in the treatment of coronary artery disease (CAD) by its anti-inflammatory effects. However, the effect of exercise training programs on salivary concentrations of high-sensitivity C-reactive protein (hs-CRP) in patients with coronary artery disease has not been well studied. The objective of this study was to evaluate the effect of phase III cardiac rehabilitation on serum and salivary levels of hs-CRP, in relation to the anthropometric measurements of obesity and the relationship between salivary and serum levels of hs-CRP in CAD male patients.

Materials and methods

Forty male volunteers (45-75 years) with CAD participated in 6 to 8 weeks of moderate intensity aerobic exercise training consisting of 45 minutes sessions of treadmill, stationary bicycle and arm ergometer. Anthropometric measurements of obesity, serum level of hs-CRP, stimulated and nonstimulated salivary level of hs-CRP were measured at the beginning, in the middle and at the end of exercise sessions.

Results

All anthropometric measurements increased (p < 0.05) following cardiac rehabilitation except waist-hip ratio. Serum hs-CRP level reduced by 36% independent to the anthropometric measurements changes. Stimulated and nonstimulated salivary hs-CRP level decreased 68 and 54%, respectively, after 24 sessions of cardiac rehabilitation. Nonstimulated salivary hs-CRP levels correlated to serum levels of hs-CRP at baseline and after 24 sessions (p < 0.05).

Conclusion

Phase III cardiac rehabilitation seems to be effective to improve serum and salivary hs-CRP concentrations independent of anthropometric measurements.

Clinical significance

Nonstimulated salivary hs-CRP measurement could be a surrogate for blood measurement of hs-CRP during cardiac rehabilitation in male patients with CAD.

How to cite this article

Jamshidpour B, Moghadam BA, Vasaghi-Gharamaleki B, Mirzaii-Dizgah I, Nejatian M. The Effects of Phase III Cardiac Rehabilitation in Serum and Salivary Hs-CRP and Anthropometric Measurements in Patients with Coronary Artery Disease. J Contemp Dent Pract 2013;14(5):819-824.


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