The Journal of Contemporary Dental Practice

Register      Login



Volume / Issue

Online First

Related articles

VOLUME 14 , ISSUE 5 ( September-October, 2013 ) > List of Articles


A Novel Treatment of Gingival Recession using a Botanical Topical Gingival Patch and Mouthrinse

William Z Levine, Noah Samuels, Meytal Elia Bar Sheshet, John T Grbic

Citation Information : Levine WZ, Samuels N, Sheshet ME, Grbic JT. A Novel Treatment of Gingival Recession using a Botanical Topical Gingival Patch and Mouthrinse. J Contemp Dent Pract 2013; 14 (5):948-953.

DOI: 10.5005/jp-journals-10024-1431

Published Online: 00-10-2013

Copyright Statement:  Copyright © 2013; Jaypee Brothers Medical Publishers (P) Ltd.


Background and aim

Current treatment of gingival recession (GR) is limited to surgical procedures. We describe a case series of 18 patients with GR who were treated with a botanical patch and rinse following standard conservative therapy.

Case series description

A total of 22 sites with GR > 1 mm were studied. Following scaling and root planing (SRP) and oral hygiene instruction, patients received two courses of patch treatment (3 days each) and botanical rinse administered twice daily throughout the treatment period. Outcome measures (GR, gingival index (GI) and gingival thickness (GT) were taken at baseline; at 1 to 2 weeks; 2 to 4 weeks; and at 6 to 8 weeks. Miller classification and plaque index (PI) were measured at baseline and at 6 to 8 weeks. At the end of the treatment period, mean GR decreased from 4.18 ± 1.74 mm to 3.31 ± 1.51 mm (20.8%); Miller grade from 1.86 ± 0.56 to 1.06 ± 0.43; GI scores from 1.45 ± 0.63 to 0.17 ± 0.38 (88.3%); and PI scores from 1.33 ± 0.59 to 0.78 ± 0.94. GT increased from 0.74 mm ± 0.40 to 1.21 ± 0.39 (63.5%). No adverse effects were reported with either the patch or rinse treatments


We observed a decrease in GR and GI scores in 18 patients (22 sites) treated with the study patch and rinse, with increased GT.

How to cite this article

Levine WZ, Samuels N, Sheshet MEB, Grbic JT. A Novel Treatment of Gingival Recession using a Botanical Topical Gingival Patch and Mouthrinse. J Contemp Dent Pract 2013;14(5):948-953.

PDF Share
  1. Root coverage procedures for the treatment of localised recession-type defects. Cochrane Database Syst Rev 2009;2:CD007161.
  2. Three-year root caries incidence and risk modeling in older adults in North Carolina. J Public Health Dent 1995;55:69-78.
  3. Gingival recession: Epidemiology and risk indicators in a representative urban Brazilian population. J Periodontol 2004;75:1377-1386.
  4. Gingival recession, gingival bleeding and dental calculus in adults 30 years of age and older in the United States, 1988-1994. J Periodontol 1999;70:30-43.
  5. Root-coverage procedures for the treatment of localized recession-type defects: a Cochrane systematic review. J Periodontol 2010;81:452-478.
  6. The etiology and prevalence of gingival recession. J Am Dent Assoc 2003;134:220-225.
  7. Gingival recession. Reappraisal of an enigmatic condition and a new index for monitoring. J Clin Periodontol 1997;24:201-205.
  8. Romano F, Peccolo DC, Debernardi C. Nonsurgical periodontal therapy of shallow gingival recession defects: evaluation of the restorative capacity of marginal gingiva after 12 months. J Periodontol 2005;76:256-261.
  9. Asiaticoside induction for cell-cycle progression, proliferation and collagen synthesis in human dermal fibroblasts. Int J Dermatol 2004;43:801-807.
  10. Effect of Centella asiatica L (Umbelliferae) on normal and dexamethasonesuppressed wound healing in Wistar Albino rats. Int J Low Extrem Wounds 2006;5:137-143.
  11. In vitro screening of five local medicinal plants for antibacterial activity using disk diffusion method. Trop Biomed 2005;2:165-170.
  12. Adjunctive periodontal treatment with Centella asiatica and Punica granatum extracts in supportive periodontal therapy. J Int Acad Periodontol 2005;7:70-79.
  13. Inhibition of proinflammatory activities of major periodontal pathogens by aqueous extracts from elder flower (Sambucus nigra). J Periodontol 2006;77:271-279.
  14. Inhibitory activity of a standardized elderberry liquid extract against clinically-relevant human respiratory bacterial pathogens and influenza A and B viruses. BMC Complement Altern Med 2011;11:16.
  15. Bactericidal and anti-inflammatory properties of a standardized Echinacea extract (Echinaforce): dual actions against respiratory bacteria. Phytomedicine 2010;17:563-568.
  16. Antioxidant and immunoenhancing effects of Echinacea purpurea. Biol Pharm Bull 2004;27:1004-1009.
  17. Alcohol extract of Echinacea pallida reverses stress-delayed wound healing in mice. Phytomedicine 2009;16:669-678.
  18. Localized reduction of gingival inflammation using site-specific therapy with a topical gingival patch. J Clin Dent 2012;23:64-67.
  19. A Novel adjuvant treatment to scaling and root planing with a topical gingival patch: a case series. Clin Adv Periodont 2012;2:123-127.
  20. A phase II trial of a transmucosal herbal patch for the treatment of gingivitis. J Am Dental Assoc 2011;142:1168-1175.
  21. Effect of an herbal mouth rinse (HM-302) in preventing periodontal inflammation in an experimental gingivitis model: a pilot study. Compendium Clin Educ Dent 2012;33:204-211.
  22. The gingival index, the plaque index and the retention index systems. J Periodontol 1967;38(Suppl 6):610-616.
  23. Current status and perspectives of mucogingival soft tissue measurement methods. J Esthet Restor Dent 2011;23:146-156.
  24. Does tooth brushing influence the development and progression of noninflammatory gingival recession? A systematic review. J Clin Periodontol 2007;34:1046-1061.
  25. Asiaticoside-induced elevation of antioxidant levels in healing wounds. Phytother Res 1999;13:50-54.
  26. Factors affecting the outcomes of coronally advanced flap root coverage procedure. J Periodontol 2005;76:1729-1734.
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.