The Journal of Contemporary Dental Practice

Register      Login

SEARCH WITHIN CONTENT

FIND ARTICLE

Volume / Issue

Online First

Archive
Related articles

VOLUME 14 , ISSUE 6 ( November-December, 2013 ) > List of Articles

RESEARCH ARTICLE

Evaluation of Gingival Inflammation in Patients using Ovulation Induction Drugs before and after Scaling

Ajay Reddy, Sanjay Vasudevan, J Valli Renuka, D Sharon Sylvia, Radhika Challa, M Padmakanth

Citation Information : Reddy A, Vasudevan S, Renuka JV, Sylvia DS, Challa R, Padmakanth M. Evaluation of Gingival Inflammation in Patients using Ovulation Induction Drugs before and after Scaling. J Contemp Dent Pract 2013; 14 (6):1165-1168.

DOI: 10.5005/jp-journals-10024-1469

Published Online: 01-12-2013

Copyright Statement:  Copyright © 2013; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Objectives

To determine and correlate the effect of clomiphene citrate, Letrozole in women undergoing infertility treatment on the gingival inflammatory status.

Materials and Methods

The present study is a randomized controlled clinical trial which consisted of 26 women using CC for three menstrual cycles, 26 women using CC for more than three cycles, 26 women using Letrozole. All subjects were clinically examined for plaque levels (Plaque Index), gingival inflammation, bleeding on probing (Gingival Index, Sulcus Bleeding Index). Scaling was done to all patients and all periodontal parameters were reassessed 1 month after scaling. The results were compared with a control group of 26 women matched for age, educational status and professional level, and oral habits and who had never used ovulation drugs.

Results

Baseline scores of all the test groups showed higher amount of plaque levels and inflammation compared to control. (p < 0.05). After scaling a significant reduction in inflammation was observed in all the test groups along with the control group (p < 0.0001), but women using the drugs showed persistence of inflammation compared to control (p < 0.01).

Conclusion

It can be concluded from the present study that the presence of elevated levels of hormones due to the effect of ovulation induction drugs may be the reason for the gingival inflammation in test groups.

How to cite this article

Vasudevan S, Renuka JV, Sylvia DS, Challa R, Padmakanth M, Reddy A. Evaluation of Gingival Inflammation in Patients using Ovulation Induction Drugs before and after Scaling. J Contemp Dent Pract 2013;14(6):1165-1168.


PDF Share
  1. Evaluation and management of infertility in woman: the internist's role. Ann Intern Med 2000;132:973-981.
  2. Medical, Ethical and Social aspects of assisted reproduction. Report of WHO meeting. Geneva: World Health Organization 2001:3-21.
  3. Ovulation induction in perspective. Hum Reprod Update 2002;8(5):449-462.
  4. The effect of elevated ovarian hormones on periodontal health: oral contraceptives and pregnancy. Women and Health 1992;20:21-30.
  5. Polymerase chain reaction analysis of oestrogen and androgen receptor expression in human gingival and periodontal tissue. Arch Oral Biol 1996;41:979-983.
  6. Periodontal diseases in child and adolescent. J Clin Periodontol 2002;29:400-410.
  7. The effect of sociocultural status on periodontal conditions in pregnancy. J Periodontol 2002;73:178-182.
  8. Experimental gingivitis during pregnancy and postpartum: clinical, endocrinological and microbiological aspects. J Clin Periodontol 1994;21:549-558.
  9. Development of a classification system for periodontal diseases and conditions. Ann Periodontol 1999;4:1-6.
  10. Hormonal influences: effects of diabetes mellitus and endogenous female sex steroid hormones on the periodontium. Periodontol 2000. 2003;32:59-81.
  11. Changes in vascular permeability after local application of sex hormones. J Periodont Res 1967;2:259-265.
  12. Changes in vascular proliferation after local application of sex hormones. J Periodont Res 1967;2:266-272.
  13. Selective estrogen receptor modulators (SERMs) in clinical practice. J Soc Gynecol Investig 2000;7:38-46.
  14. Effect of chlomiphene citrate on ovulation after treatment withdrawl. Arch Gynecol Obstet 1998;261:117-120.
  15. Experimental gingivitis during pregnancy and postpartum: clinical, endocrinological and microbiological aspects. J Clin Periodontol 1994;21:549-558.
  16. A longitudinal study from prepuberty to puberty gingivitis. Correlation between the occurrence of Prevotella intermedia and sex hormones. J Clin Periodontol 1994;21:658-665.
  17. Effects of Estradiol and progesterone on bacteriodes melanogenicus and bacteroides gingivalis. Infect Immun 1982;35:256-263.
  18. The effects of ovulation induction during infertility treatment on gingival inflammation. J Periodontol 2004 Jun;75(6):805-810.
  19. The relationship between infections and adverse pregnancy outcomes: an overview. Ann Periodontol 2001;6:153-163.
  20. Periodontal infection as a possible risk factor for preterm low birth weight. J Periodontol 1996;67(10):1103-1113.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.