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VOLUME 15 , ISSUE 1 ( January-February, 2014 ) > List of Articles

RESEARCH ARTICLE

An Analysis of Biopsy-proven Tongue Lesions among 8,105 Dental Outpatients

Mojgan Alaeddini, Roohollah Barghammadi, Shahroo Etemad-Moghadam

Citation Information : Alaeddini M, Barghammadi R, Etemad-Moghadam S. An Analysis of Biopsy-proven Tongue Lesions among 8,105 Dental Outpatients. J Contemp Dent Pract 2014; 15 (1):1-7.

DOI: 10.5005/jp-journals-10024-1478

Published Online: 01-02-2014

Copyright Statement:  Copyright © 2014; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Aim

The aim of the present study was to analyze data on the characteristics of tongue lesions in dental patients seeking care at the Oral Pathology Service of Tehran University of Medical Sciences, from 1985-2010.

Materials and methods

Demographic data and histopathologic diagnoses were recorded for all lesions that were documented as occurring on the tongue according to the patient records in our department. Statistical analysis included chi-square, t-, and Fisher's exact tests. A 95% confidence interval (CI) was calculated, and p < 0.05 was considered significant.

Results

Tongue lesions constituted 6.3% of all received specimens which included 46 different defects. The most common lesions were lichen planus (LP), irritation fibroma (IF), squamous cell carcinoma (SCC) and pemphigus vulgaris (PV). Tongue lesions were significantly more common in women compared to men (CI = 0.65-0.94, p = 0.02). Mean age (47 years) did not differ between male and female subjects (CI = −2.49 – 3.93, p = 0.06). The dorsal surface followed by the lateral aspect was the most common site for tongue lesions.

Conclusion

It seems that dental practitioners should be perceptive of LP, IF, SCC and PV, when examining the tongue. Histopathologic analysis is essential for achieving final diagnosis in a considerable number of lesions that commonly occur on this organ.

Clinical significance

Access to demographic/prevalence data in different populations may be useful in clinical settings and could be complimented by histopathologic diagnosis in most instances. The present findings can be compared with those obtained from other epidemiologic studies in this field resulting in valuable data which may be used in several types of investigations.

How to cite this article

Alaeddini M, Barghammadi R, Eshghyar N, Etemad-Moghadam S. An Analysis of Biopsyproven Tongue Lesions among 8,105 Dental Outpatients. J Contemp Dent Pract 2014;15(1):1-7.


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  1. Functional tongue reconstruction. Curr Opin Otolaryngol Head Neck Surg 2002 Aug;10(4):266-272.
  2. The tongue: structure and function relevant to disease and oral health. SADJ 2003 Oct;58(9):375-376, 380-383.
  3. Histology for pathologists. 3rd ed. Philadelphia, Pa, Lippincott Williams and Wilkins, 2006.
  4. Tongue lesions in the pediatric population. Otolaryngol Head Neck Surg 2001 Feb;124(2):164-169.
  5. Lingual malignancies. Improving early detection and diagnosis. Postgrad Med 1984 Mar;75(4):173-180, 185-186.
  6. Radiologic-pathologic correlation of unusual lingual masses: Part II: benign and malignant tumours. Korean J Radiol 2001 Jan-Mar;2(1):42-51.
  7. Put out your tongue! The role of clinical insight in the study of the history of medicine. Med Hist 2011 Jul;55(3):301-306.
  8. The prevalence of tongue lesions in 5150 Turkish dental outpatients. Oral Dis 2003 Jul;9(4):188-195.
  9. Tongue lesions in a Jordanian population. Prevalence, symptoms, subject›s knowledge and treatment provided. Med Oral Patol Oral Cir Bucal 2011 Sep 1;16(6):e745-749.
  10. The prevalence of tongue lesions in Malaysian dental outpatients from the Klang Valley area. Oral Dis 2011 Mar;17(2):210-216.
  11. An epidemiologic study of tongue lesions in 1901 Iranian dental outpatients. J Contemp Dent Pract 2008 Nov. 1;9(7):73-80.
  12. Prevalence of oral lesions among Saudi dental patients. Ann Saudi Med 2009 Sep-Oct;29(5):365-368.
  13. Prevalence study of tongue lesions in a Hungarian population. Community Dent Oral Epidemiol 1993 Aug;21(4):224-226.
  14. The prevalence of tongue lesions in Libyan adult patients. J Clin Exp Dent 2010 Nov;2(4):e163-168.
  15. Epidemiologic and clinicopathologic characteristics of tongue cancer in Iranian patients. Acta Med Iran 2011;49(1):44-48.
  16. Oral mucosal conditions in elderly dental patients. Oral Dis 2002 Jul;8(4):218-223.
  17. Prevalence and risk factors associated with geographic tongue among US adults. Oral Dis 2006 Jul;12(4):381-386.
  18. WHO pathology and genetic of head and neck tumours. Lyon: IACR 2005.
  19. Oral and Maxillofacial Pathology. 3rd ed. Philadelphia, Saunders, 2008.
  20. Oral pathology clinical pathologic correlations. 5th ed. Missouri: Saunders 2008.
  21. The prevalence of oral mucosal lesions in US adults: data from the Third National Health and Nutrition Examination Survey, 1988-1994. J Am Dent Assoc 2004 Sep;135(9):1279-1286.
  22. An analysis of oral biopsies extracted from 1995 to 2009, in an oral medicine and surgery unit in Galicia (Spain). Med Oral Pathol Oral Cir Bucal 2012 Jan 1;17(1):e16-22.
  23. Prevalence of biopsied oral lesions in a Department of Oral Surgery (2007-2009). J Clin Exp Dent 2011 Apr;3(2):e73-77.
  24. Irritation fibroma of the oral mucosa: a clinicopathological study of 129 lesions in 124 cases. Oral Med Pathol 2001;6(2):91-94.
  25. Benign tumours of the oral mucosa: a study of 300 patients. Med Oral Pathol Oral Cir Bucal 2008 Mar 1;13(3):E161-166.
  26. Reactive hyperplasia of the oral cavity in Kerman province, Iran: a review of 172 cases. Br J Oral Maxillofac Surg 2007 Jun;45(4):288-292.
  27. Intraoral squamous cell carcinoma. Epidemiologic patterns in Connecticut from 1935 to 1985. Cancer 1990 Sep 15;66(6):1288-1296.
  28. Prevalence and significance of human papillomavirus in oral tongue cancer: the Mayo Clinic experience. J Oral Maxillofac Surg 2008 Sep;66(9):1875-1880.
  29. Clinical evaluation of oral lesions associated with dermatologic diseases. An Bras Dermatol 2010 Apr;85(2):150-156.
  30. The oral lesions of lichen planus: observations on 100 cases. Oral Surg Oral Med Oral Pathol 1961 Feb;14(2):164-181.
  31. Morphometric analysis of the dorsum linguae in patients with oral lichen planus. Med Oral Pathol Oral Cir Bucal 2009 Aug 1;14(8):e388-392.
  32. Clinical guidelines in early detection of oral scc arising in oral lichen planus: a 5 years experience. Oral Oncol 2001 Apr;37(3):262-267.
  33. Localised fibrous overgrowths of the oral mucosa. Br J Oral Surg 1967 Nov;5(2):86-92.
  34. Differential diagnosis of tongue lesions. Quintessence Int 2003 May;34(5):331-342.
  35. Intraoral carcinomas in Maiduguri, north-eastern Nigeria. Oral Dis 2005 Nov;11(6):379-385.
  36. Oral cancer report from Northeastern Hungary. Pathol Oncol Res 2008 Mar;14(1):85-92.
  37. Epidemiology of squamous cell carcinoma of the oral cavity in Iran. J Craniofac Surg 2008 Nov;19(6):1699-1702.
  38. An epidemiological study of immune-mediated skin diseases affecting the oral cavity. An Bras Dermatol 2011 Sep-Oct;86(5):905-909.
  39. Oral pemphigus vulgaris preceding cutaneous lesions: recognition and diagnosis. J Am Dent Assoc 2000 Aug;131(8):1156-1160.
  40. Oral presentation of pemphigus vulgaris and its response to systemic steroid therapy. Oral Surg Oral Med Oral Pathol 1992 Jul;74(1):54-57.
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