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VOLUME 16 , ISSUE 3 ( March, 2015 ) > List of Articles

RESEARCH ARTICLE

Eradication of Gastric Helicobacter pylori ameliorates Halitosis and Tongue Coating

Svetislav Zaric, Bozidar Bojic, Branka Popovic, Jelena Milasin

Citation Information : Zaric S, Bojic B, Popovic B, Milasin J. Eradication of Gastric Helicobacter pylori ameliorates Halitosis and Tongue Coating. J Contemp Dent Pract 2015; 16 (3):205-209.

DOI: 10.5005/jp-journals-10024-1662

Published Online: 01-03-2015

Copyright Statement:  Copyright © 2015; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Background

The influence of gastric Helicobacter pylori infection on the development of oral pathoses remains unclear. The aim of this study is to examine the influence of gastric H. pylori infection on occurrence of halitosis and coated tongue.

Materials and methods

Ninety-eight patients with dyspepsia were included in the study and their salivary samples and gastric biopsies were analyzed for the presence of H. pylori by Nested-PCR. Halitosis and coated tongue were assessed at the initial examination and 3 months after systemic eradication therapy against H. pylori.

Results

Gastric biopsies of 66 patients were positive for H. pylori. Only one saliva sample was H. pylori positive. At initial examination, halitosis was observed in 20 patients (30.3%) out of 66 who had gastric H. pylori infection and in only 3 patients (9.4%) out of 32 without H. pylori infection (p = 0.0236). Coated tongue was diagnosed in 18 (27.2%) patients with the infection compared to only 2 (6.25%) patients negative for gastric H. pylori (p = 0.0164). Patients with gastric infection were treated with the triple eradication therapy (Amoxicillin, Clarythromycin, Pantoprazol) and their gastric biopsies and oral status were examined 3 months later. Halitosis was significantly more prevalent in the group of patients with persistent H. pylori infection (42.1%) compared to only 6.4% of patients in the group where infection was successfully eradicated (p = 0.0012). Coated tongue was diagnosed in 47.4% of patients where H. pylori was still present after eradication therapy and in only 6.4% where eradication succeeded (p = 0.0003).

Conclusion

Our findings suggest that eradication of gastric H. pylori significantly alleviates halitosis and coated tongue, the two oral conditions that may be considered as extragastric manifestations of this common chronic bacterial infection.

How to cite this article

Zaric S, Bojic B, Popovic B, Milasin J. Eradication of Gastric Helicobacter pylori ameliorates Halitosis and Tongue Coating. J Contemp Dent Pract 2015;16(3):205-209.


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