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VOLUME 16 , ISSUE 3 ( March, 2015 ) > List of Articles

RESEARCH ARTICLE

Comparative Evaluation and Correlation of Salivary Total Antioxidant Capacity and Salivary pH in Caries-free and Severe Early Childhood Caries Children

Meenakshi Nankar, Hrishikesh Walimbe, Mohammed Nadeem Ahmed Bijle, Sneha Muchandi, Srishti Chaturvedi, Priyanka Karekar

Citation Information : Nankar M, Walimbe H, Bijle MN, Muchandi S, Chaturvedi S, Karekar P. Comparative Evaluation and Correlation of Salivary Total Antioxidant Capacity and Salivary pH in Caries-free and Severe Early Childhood Caries Children. J Contemp Dent Pract 2015; 16 (3):234-237.

DOI: 10.5005/jp-journals-10024-1667

Published Online: 00-03-2015

Copyright Statement:  Copyright © 2015; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Background

Dental caries is a major problem in preschool children. The contribution of saliva in providing defense during caries process is of primary importance. pH buffer capacity through bicarbonate, phosphate and protein buffer systems have universal acceptance as a caries defense mechanism. Antioxidant capacity of saliva can constitute a first line of defense against chronic degenerative diseases including dental caries. Till date, no study is presented with salivary antioxidant capacity of younger children affected with severe early childhood caries with its salivary pH correlation. Hence, this study was carried out to compare, evaluate and correlate the salivary total antioxidant capacity (TAC) and salivary pH of children with caries-free and severe early childhood caries.

Materials and methods

Fifty children from ages 3 to 5 years divided into two study groups had undergone screening. Group I (n = 25) with severe early childhood caries (S-ECC) and group II (n = 25) who were caries free. Unstimulated whole saliva of subjects were in the collection during the study by draining method. Salivary pH determination of saliva samples was done using pH indicator paper strips. The TAC was done using an antioxidant assay with the help of a spectrophotometer at wavelength 532 nm. The means of salivary pH and TAC were subjected to analysis using unpaired student ‘t’ test and correlation was determined using Pearsons correlation coefficient analysis.

Results

Mean salivary pH was higher in group II (7.46 ± 0.37). Mean TAC was greater in group I (1.82 ± 0.19). A statistically significant negative correlation as seen between TAC and salivary pH in S-ECC patients.

Conclusion

The study concludes that salivary TAC increases in patients with S-ECC are by that showing a high indirect relationship with salivary pH.

How to cite this article

Muchandi S, Walimbe H, Bijle MNA, Nankar M, Chaturvedi S, Karekar P. Comparative Evaluation and Correlation of Salivary Total Antioxidant Capacity and Salivary pH in Caries-free and Severe Early Childhood Caries Children. J Contemp Dent Pract 2015;16(3):234-237.


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