Oral submucous fibrosis (OSF) and quid associated oral lichenoid lesions (QOLL) are caused because of areca nut chewing and both show very characteristic histological changes. The present study aims to determine the histopathological presence of lichenoid features in cases of OSF as well as to determine the presence of fibrosis in cases of QOLL.
Materials and methods
The study involved the retrospective analysis of hematoxylin and eosin stained slides of OSF (n = 50) and QOLL (n = 16).
Results
Seven cases of OSF revealed histopathological features of lichenoid reaction and four cases of QOLL revealed the presence of fibrosis in the underlying connective tissue.
Conclusion
This study put forths a new finding that is, the presence of concomitant disease processes seen in the same patient at a histological level. It thus, stresses the need to evaluate all cases of OSF and QOLL for additional features which may be induced by areca nut chewing.
How to cite this article
Yanduri S, Kumar VB, Suma S, Madhura MG. Lichenoid Features and Fibrosis: Coexistence in Quid-induced Oral Lesions. J Contemp Dent Pract 2015;16(5):389-393.
Oral submucous fibrosis. Oral Surg Oral Med Oral Pathol 1966;22(6):764-779.
Oral mucosal lesions associated with betel quid, areca nut and tobacco chewing habits: consensus from a workshop held in Kuala Lumpur, Malaysia, November 25-27, 1996. J Oral Pathol Med 1999;28(1):1-4.
Molecular pathogenesis of oral submucous fibrosis—a collagen metabolic disorder. J Oral Pathol Med 2005;34(6):321-328.
Histopathologic features of oral submucous fibrosis: a study of 35 biopsy specimens. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008;106(4):556-560.
Oral lichenoid contact lesions induced by areca nut and betel quid chewing: a mini review. J Investig Clin Dent 2012;3(3):163-166.
Evaluation of proliferative potential in oral lichen planus and oral lichenoid lesions using immunohistochemical expression of p53 and Ki67. Oral Oncol 2006;42:475-480.
Oral lichen planus and lichenoid reactions: etiopathogenesis, diagnosis, management and malignant transformation. J Oral Sci 2007;49(2):89-106.
Cys-X-Cys ligand 9 might be an immunological factor in the pathogenesis of oral submucous fibrosis and its concomitant oral lichenoid lesion. Clin Oral Investig 2013;17(4):1251-1258.
Oral submucous f ibrosis: a clinicopathologic review of 205 cases in Indians. Oral Maxillofac Surg 2011;15(1):15-19.
Betel quid-induced oral lichen planus: a case report. Cutis 2003;71(4):307-311.
Prevalence of oral mucosal lesions in dental patients with tobacco smoking, chewing, and mixed habits: a cross-sectional study in South India. J Family Community Med 2013;20(2):130-135.
An oral lichen planus like lesion in Indian betel-tobacco chewers. Scand J Dent Res 1980;88:244-249.
The possible premalignant character of oral lichen planus and oral lichenoid lesions: a prospective five-year follow-up study of 192 patients. Oral Oncol 2007;43(8):742-748.
Areca nut and betel quid chewing among South Asian immigrants to Western countries and its implications for oral cancer screening. Rural Remote Health 2009;9(2):1118.
A universal diagnostic criteria for oral lichen planus: an exigency! Int J Contemp Dent Med Rev 2014, (2014). Article ID 041214 doi: 10.15713/ins.ijcdmr.15.
