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VOLUME 16 , ISSUE 6 ( June, 2015 ) > List of Articles


Power Hydrogen Evaluation of Apexification Materials: EndoCal 10, Mineral Trioxide Aggregate and Calasept Plus

Ersan Çiçek, Emre Bodrumlu

Citation Information : Çiçek E, Bodrumlu E. Power Hydrogen Evaluation of Apexification Materials: EndoCal 10, Mineral Trioxide Aggregate and Calasept Plus. J Contemp Dent Pract 2015; 16 (6):463-467.

DOI: 10.5005/jp-journals-10024-1707

Published Online: 00-06-2015

Copyright Statement:  Copyright © 2015; Jaypee Brothers Medical Publishers (P) Ltd.



The present study was to evaluate pH values of apexification materials.

Materials and methods

The materials were placed in 1 cm long and 4 mm diameter tubes. After sample immersion, glass flasks were hermetically sealed with rubber caps to attenuate any effects of external environmental factors and maintained at 37°C. The power hydrogen of the pastes was measured 1 hour, 3 hours, 8 hours, 24 hours, 72 hours and 7 days after preparation. pH was calibrated with solutions of known pH (7.0). Mann-Whitney test were used to determine significant differences.


The mean pH of all medications was < 12.0 throughout the experiment. At 24 hours, EndoCal 10 had the highest pH of all the materials (p < 0.05).


A ccording t o t he r esults o btained, i t m ay b e concluded that calcium oxide (EndoCal 10) presented the higest pH compared with mineral trioxide aggregate (MTA) and Calasept Plus [Ca(OH)2].

Clinical significance

Apexification is an important treatment in immature teeth. For this reason, used materials in apexification should have some properties, such as high pH and stimulating to be hard tissue. Therefore, the material should be chosen carefully in apexification of immature teeth.

How to cite this article

Çiçek E, Bodrumlu E. Power Hydrogen Evaluation of Apexification Materials: EndoCal 10, Mineral Trioxide Aggregate and Calasept Plus. J Contemp Dent Pract 2015;16(6):463-467.

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  1. Apexification: a review. Dent Traumatol 2005;21:1-8.
  2. Glossary of endodontic terms. 7th edn. Chicago: American association of Endodontists; 2003.
  3. Pediatric Dentistry: infancy through adolescence. 3rd ed. Philadelphia; 1999. p. 152-161.
  4. Calcium hydroxide pastes: classification and clinical indications. Int Endod J 1999;32:257-282.
  5. The antibacterial effect of camphorated paramonochlorophenol, camphorated phenol and calcium hydroxide in the treatment of infected root canals. Endod Dent Traumatol 1985;1:170-175.
  6. Effects of calcium hydroxide and sodium hypochlorite on the dissolution of necrotic porcine muscle tissue. J Endod 1988;14:125-127.
  7. Influence on pH of vehicle containing glycerin used with calcium hydroxide. Dent Traumatol 2003;19:132-138.
  8. Intracanal medication. In: Ingle JI, Bakland LK, editors. Endodontics. 4th ed. Baltimore: Williams and Wilkins; 1994. p. 627-640.
  9. Effect of calcium hydroxide on bacterial lipopolysaccharide. J Endod 1993;19:76-78.
  10. Alteration of biological properties of bacterial lipopolysaccharide by calcium hydroxide. J Endod 1994;20:127-129.
  11. TNF-alpha release in monocytes after exposure to calcium hydroxide treated E. coli LPS. Int Endod J 1997;30:155-159.
  12. Radiographic evaluation of the effect of endotoxin (LPS) plus calcium hydroxide on apical and periapical tissues of dogs. J Endod 2002;28:694-646.
  13. Calcium hydroxide reduces lipopolysaccharide-stimulated osteoclast formation. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2003;95:348-354.
  14. The pH changes of four different calcium hydroxide mixtures used for intracanal medication. J Oral Rehabil 2003;30:436-439.
  15. Use of MTA for orthograde obturation of nonvital teeth with open apices: report of two cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007;104:98-101.
  16. PH changes at the surface of root dentin after intracanal dressing with calcium oxide and calcium hydroxide. J Endod 2001;27(1):43-45.
  17. The properties of Endocal 10 and its potential impact on the structural integrity of the root. J Endod 2004;30(3):159-162.
  18. Calcium hydroxide in root canal therapy: a review. Brit Dent J 1977;142:277-283.
  19. The pH changes of four different root canal sealers after mixing at various time intervals in vitro. J Contemp Dent Pract 2004;5:71-78.
  20. pH measurement of root canal sealers. J Endod 1998;24:236-238.
  21. Hydroxyol ions from set endodontic sealers containing calcium hydroxide. J Endod 1988;14:588-591.
  22. Calcium hydroxide: Root resorption and Perio-Endo lesions. Br Dent J 1985;158:325-334.
  23. Mechanism of the action of calcium and hydroxyl ions of calcium hydroxide on tissue and bacteria. Braz Dent J 1995;6:685-690.
  24. pH and calcium ion release of 2 root-end filling materials. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2003;95:345-357.
  25. Mineral trioxide aggregate: a comprehensive literature review-part I: chemical, physical, and antibacterial properties. J Endod 2010;36:16-27.
  26. Effect of different root canal sealers on repair of teeth with chronic periradicular periodontitis. Int End J 1998;31:85-89.
  27. Antibacterial activity of calcium hydroxide-containing endodontic sealers on Enterococcus faecalis in vitro. Int End J 1997;30:397-402.
  28. Comparative evaluation of endodontic management of teeth with unformed apices with mineral trioxide aggregate and calcium hydroxide. J Dent Child 2006;73:79-85.
  29. Monoblocks in root canals: a hypothetical or a tangible goal. J Endod 2007;33:391-398.
  30. The effect of three vehicles on the pH of calcium hydroxide. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1982;54:560-565.
  31. Evaluation of pH and calcium ion release of Acroseal sealer in comparison with Apexit and Sealapex sealers. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007;103:86-91.
  32. The influence of calcium chloride on the setting time, solubility, disintegration, and pH of mineral trioxide aggregate and white Portland cement with a radiopacifier. J Endod 2009;35:550-554.
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