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VOLUME 19 , ISSUE 1 ( January, 2018 ) > List of Articles

ORIGINAL RESEARCH

Children’s Menu Diversity: Influence on Fluoride Absorption and Excretion

Andreany M Cavalli, Flavia M Florio

Citation Information : Cavalli AM, M Florio F. Children’s Menu Diversity: Influence on Fluoride Absorption and Excretion. J Contemp Dent Pract 2018; 19 (1):30-36.

DOI: 10.5005/jp-journals-10024-2207

License: CC BY-NC 3.0

Published Online: 01-01-2018


Abstract

Aim: The aim of this study is to determine the influence of children’s menu diversity on the absorption and excretion of fluoride. Materials and methods: The experimental, longitudinal, quantitative study was carried out in a city without fluoridation in water supply. A total of 16 adult volunteers (>63.9 kg) participated in the study who, after a 12-hour fast, ingested two types of children’s meals, whose quantity and diversity were determined after weighing the meals best consumed by children at a kindergarten in Campinas, São Paulo: Simple child meal (SCM; n = 8) and hearty child meal (HCM; n = 8). The fluoride gel residual after professional application (12,300 ppm, 30.75 mg F, pH = 4.65) was simulated 15 minutes after feeding. Saliva samples (in time intervals of 0, 15, 30, and 45 minutes and 1, 2, 3, 4, 6, and 12 hours after ingestion of the fluorine solution) and urine of the volunteers were analyzed at 24 hours. Fluoride concentrations were determined using a selective ion electrode. Data were analyzed by analysis of variance for repeated measurements (PROC MIXED)/Tukey–Kramer. Results: The concentrations of fluoride in saliva at 0 and 15 minutes and after 6 hours were the same between groups (p > 0.05). From 30 minutes to 4 hours after ingestion, the SCM group showed a higher concentration of fluoride in the saliva, which has a higher absorption (p < 0.05). The fluoride concentration in the urine did not differ between groups at both collection times (p > 0.05), and for both, the fluoride concentration in the urine increased in the final measurement (p < 0.05). Conclusion: The children’s menu diversity influenced the absorption of fluoride so that the topical application of fluoride should be performed in infants fed preferably after the fuller diet and following the established guidelines to ensure the safety of the procedure. Clinical significance: Knowledge of the influence of the children’s menu diversity on fluoride metabolism after professional application is important so that the actions of fluoride therapy may be planned in a safer manner and be based on the reality of the universe of children.


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  1. O’Mullane DM, Baez RJ, Jones S, Lennon MA, Petersen PE, Rugg-Gunn AJ, Whelton H, Whitford GM. Fluoride and oral health. Community Dent Health 2016 Jun;33(2):69-99
  2. Pharmacokinetics of fluoride in man and its clinical relevance. J Dent Res 1990 Feb;69 Spec No:550-555
  3. Limitações do uso de fluoreto em Odontologia: toxicidade aguda e toxicidade crônica. J Assoc Bras Odontol 2009 Jan-Feb;117:10-11
  4. Acute toxicity of ingested fluoride. Fluoride intake, metabolism and toxicity. In: Buzalaf MA, editor. Fluoride and the oral environment. Monogr in oral science. Vol. 22. Basel: Karger; 2011. pp. 66-80
  5. Accidental ingestion of NaF tablets by children–report of a poison control center and one case. Int J Clin Pharmacol Ther Toxicol 1982 Jul;20(7):334-338
  6. 1989 annual report of the American association of poison control centers national data collection system. Am J Emerg Med 1990 Sep;8(5):394-442
  7. Acute and chronic fluoride toxicity. J Dent Res 1992 May;71(5):1249-1254
  8. Fatality due to acute fluoride poisoning in the workplace. Leg Med (Tokyo) 2004 Jul;6(3):197-200
  9. Formation of alkalisoluble fluoride on the surface of human dental enamel after treatment with fluoridated gels: influence of the pH variation and of the treatment time. J Clin Pediatr Dent 2000 Summer;24(4):303-307
  10. Fluoride levels in breast milk and infant foods. J Clin Pediatr Dent 2000 Summer;24(4):299-302
  11. Fluoride content in toothpastes commercialized for children in Chile and discussion on professional recommendations of use. Int J Paediatr Dent 2013 Mar;23(2):77-83
  12. Absorção de flúor e nefrotoxicidade após a aplicação tópica de gel. Rev Assoc Paul Cirur Dent 1987 Jan-Feb;41(1):57-89
  13. Influence of milk and food on fluoride bioavailability from NaF and Na2FPO3 in man. J Dent Res 1989 Jan;68(1):72-77
  14. Effect of gastric contents on the bioavailability of fluoride in humans. Pediatr Dent 1990 Jul-Aug;12(4):237-240
  15. Low-fluoride dentifrice and gastrointestinal fluoride absorption after meals. J Dent Res 2005 Dec;84(12):1133-1137
  16. Assessment of the influence of meal type on fluoride absorption due to ingestion of professionally applied gels. J Contemp Dent Pract 2016 Jun;17(6):451-456
  17. Aconselhamento em alimentação infantil: um estudo de intervenção. J Pediatr (Rio J) 2008 Jan-Feb;84(1):75-82
  18. Pesquisa Nacional de Saúde. Percepção do Estado de Saúde, Estilos de Vida e Doenças Crônicas. Brasil: IBGE; 2013. Available from: ftp://www.ftp.ibge.gov.br/PNS/2013/pns2013.pdf
  19. Condições socioeconômicas e padrões alimentares de crianças de 4 a 11 anos: estudo SCAALA—Salvador/Bahia. Rev Bras Saude Mater Infant 2011 Jan-Mar;11(1):41-49
  20. Indicações de odontopediatras quanto ao uso de flúor tópico por crianças entre zero e seis anos de idade: Dados para a elaboração de um protocolo de ações. Salusvita 2007;27(3): 373-392
  21. Fluoride varnishes for preventing dental caries in children and adolescents. Cochrane Database Syst Rev 2013 Jul;7:CD002279
  22. Ministé da Saúde. Secretaria de Atenção à Saúde. Departamento de Atenção Básica. Coordenação de Saúde Bucal. Política Nacional de Saúde Bucal. Brasília: Diretrizes da Política Nacional de Saúde Bucal; 2004
  23. The effect of smoking on the bioavailability of metronidazole in plasma and saliva. J Am Dent Assoc 2012 Feb;143(2):149-156
  24. Prevenção da cárie dental com aplicações tópicas semestrais de flúor-fosfato acidulado. Rev Saúde Pública 1993;27(4):277-290
  25. ; Fejerskov, O.; Cury, JA.; Clarkson, B. Fluoride in caries control. In: Fejerskov O, Kidd EA, editors. Dental caries: the disease and its clinical management. 2nd ed. Oxford: Blackwell Munksgaard; 2008. pp. 287-323
  26. Influência da intensidade da dor sobre as respostas nas escalas unidimensionais de mensuração da dor em uma população de idosos e de adultos jovens. Semin 2008 Jul-Dec;29(2):201-212
  27. Análise da aplicabilidade de três instrumentos de avaliação de dor em distintas unidades de atendimento: ambulatório, enfermaria e urgência. Rev Bras Reumatol 2011;51(4):299-308
  28. Metabolismo de flúor após a ingestão de dentifrício. RGO Rev Gaúcha Odontol 1986 Sep-Oct;34(5):425-427
  29. Fluoride concentrations in saliva after singler oral doses and their relation to plasma fluoride. Scand J Dent Res 1977 Jan;85(1):16-17
  30. Mensuração da acidez de bebidas industrializadas não lácteas destinadas ao público infantil. Rev Odontol UNESP 2012 Mar-Apr;41(2):76-80
  31. Topical fluoride for caries prevention: executive summary of the updated clinical recommendations and supporting systematic review. J Am Dent Assoc 2013 Nov;144(11):1279-12791
  32. ADA clinical recommendations on topical fluoride for caries prevention. Evid Based Dent 2014 Jun;15(2):38-39
  33. Factors influencing fluoride ingestion from dentifrice by children. Community Dent Oral Epidemiol 2011 Oct;39(5):426-432
  34. Acidulated phosphate fluoride application changes the protein composition of human acquired enamel pellicle. Caries Res 2013 Apr;47(3):251-258
  35. Alimentação saudável: Percepções dos educadores de instituições infantis. Rev Bras Crescimento Desenvolv Hum 2008 Aug;18(2):126-134
  36. A ingestão do flúor por crianças pela água e dentifrício. Rev Saúde Pública 2001 Aug;35(6):576-581
  37. Ingestion of fluoride from dentifrices by young children and fluorosis of the teeth–a literature review. J Clin Pediatr Dent 2011 Winter;36(2):111-121
  38. Absorption of fluoride through the oral mucosa of rats. Arch Oral Biol 1968 Jun;13(6):619-623
  39. ; Silverstone, LM. Fluoride in dentistry. Chapter 7. Copenhagen: Munksgaarol; 1988. pp. 150-170
  40. ; Whitford, GM. Fluoride metabolism. In: Buzalaf MA, editor. Fluoride and the oral environment. Monograph in oral science. Vol. 22. Basel: Karger; 2011. pp. 20-36
  41. Pharmacokinetics of fluoride gels in children and adults. Caries Res 1981;15(3):213-220
  42. Total fluoride intake of infants. Pediatrics 1979 Mar;63(3):460-466
  43. Análise sumária de urina de rotina: por que e para quê? Rev Port Med Geral Fam 2013 Jul;29(4):244-248.
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