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VOLUME 19 , ISSUE 11 ( November, 2018 ) > List of Articles


Comparative Evaluation of Different Bone Markers in Peri-implant Crevicular Fluid of Immediate Loaded and Nonloaded Dental Implants

Md Imran Ul Haque, Puneet Sharma, Aditya Tiwari, Sambit Subhas, Manu Rana

Keywords : Bone markers, Crevicular fluid, Immediate loaded dental implants

Citation Information : Haque MI, Sharma P, Tiwari A, Subhas S, Rana M. Comparative Evaluation of Different Bone Markers in Peri-implant Crevicular Fluid of Immediate Loaded and Nonloaded Dental Implants. J Contemp Dent Pract 2018; 19 (11):1341-1345.

DOI: 10.5005/jp-journals-10024-2429

License: CC BY-NC 4.0

Published Online: 01-03-2019

Copyright Statement:  Copyright © 2018; The Author(s).


Aim: The present study was conducted to determine different bone markers in immediate loaded and nonloaded dental implants. Materials and methods: It comprised of 60 patients (males–30, females–30) which were divided into two groups of 30 each. Group, I received immediate loaded dental implants, and group II received non-loaded dental implants. Modified bleeding on probing index, peri-implant sulcus depth was assessed in both groups at 1 month, 2 months, 3 months and 4 months. The crevicular fluid was obtained to determine bone markers levels such as transforming growth factor-alpha (TGF-á), osteocalcin (OCN), osteopontin (OPN), parathyroid hormone (PTH) and osteoprotegerin (OPG). Results: Both groups revealed non- significant difference in modified bleeding on probing index and peri-implant sulcus depth (p > 0.05). Bone markers found to be elevated more in group I as compared to group II. However, the difference was non- significant (p > 0.05). Conclusion: Transforming growth factor alpha (TGF-á), OCN, OPN, OPG and PTH and parathyroid hormone (PTH)levels were higher in immediate loaded dental implants as compared to nonloaded dental implants. Clinical significance: Immediate loaded dental implants showed an increase in expression of bone markers such as TNF-á, OCN, OPN, PTH and OPG which may be useful in deciding future of immediate loaded dental implants

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