The Journal of Contemporary Dental Practice

Register      Login

SEARCH WITHIN CONTENT

FIND ARTICLE

Volume / Issue

Online First

Archive
Related articles

VOLUME 19 , ISSUE 11 ( November, 2018 ) > List of Articles

ORIGINAL ARTICLE

Clinical Evaluation of 10% Hydrogen Peroxide on Tooth Sensitivity and Effectiveness in at Home Dental Bleaching

Kaprice Chemin, Márcia Rezende, Fábio M Milan, Thereza B Dantas, Kátia do N Gomes, Stella Kossatz

Keywords : Dental bleaching, Dentin sensitivity, Hydrogen peroxide

Citation Information : Chemin K, Rezende M, Milan FM, Dantas TB, Gomes KD, Kossatz S. Clinical Evaluation of 10% Hydrogen Peroxide on Tooth Sensitivity and Effectiveness in at Home Dental Bleaching. J Contemp Dent Pract 2018; 19 (11):1376-1380.

DOI: 10.5005/jp-journals-10024-2435

License: CC BY-NC 4.0

Published Online: 00-11-2018

Copyright Statement:  Copyright © 2018; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Aim: The purpose of this study was to evaluate the dental effect and sensitivity of at-home dental bleaching with 10% hydrogen peroxide (H2O2). Materials and methods: Twenty volunteers with A2 or darker central incisors were selected for this study. Was used 10% H2O2 for thirty minutes twice a day, for two weeks. Shade evaluation was assessed visually by the value-oriented shade guide Vita Classical shade guide, Vita Bleachedguide 3D-MASTER and by the Easyshade spectrophotometer at baseline, during bleaching (first and second weeks), and post-bleaching (one month). The perceptions of sensitivity were recorded by the patients through the numerical rating scale (0 to 4) and 0 to 10 visual analog scales daily. Data from the shade guide units was subjected to a one way repeated measures (RM) analysis of variance (ANOVA) test (á = 5%). The overall ÄE, absolute risk and intensity of tooth sensitivity were calculated as well as the 95% confidence interval. Results: The absolute risk of tooth sensitivity was 65% and the intensity was mild. Data from ÄSGU and ÄE after 1 month of bleaching for H2O2 10% showed significant whitening, 4 units for Vita Classical, 5 units for Vita Bleachedguide and 9.7 units for spectrophotometer. Conclusion: At-home bleaching using 10% hydrogen peroxide is effective in 14 days of bleaching. The most common adverse events were mild tooth sensitivity, and no subjects discontinued use early because of a treatment-related adverse event. Clinical significance: At-home dental bleaching with 10% hydrogen peroxide gel reduces the time of use of the tray, maintaining the effectiveness with low intensity of dental sensitivity. Brazilian clinical trials registry (REBEC) RBR-45xmzj.


PDF Share
  1. Kihn PW. Vital Tooth Whitening. Dent Clin N Am 2007 Apr; 51(2):319-331.
  2. Matis BA, Wang G, Matis JI, Cook NB, Eckert GJ. White diet: is it necessary during tooth whitening? Oper Dent 2015 May- Jun; 40(3):235-240.
  3. Perdigão J, Baratieri LN, Arcari GM. Contemporary trends and techniques in tooth whitening: a review. Pract Proced Aesthet Dent 2004 Apr; 16(3):185-192
  4. Browning, WD, Blalock, JS, Frazier, KB, Downey, MC, Myers, ML. Duration and timing of sensitivity related to bleaching. J Esthet Restor Dent 2007 Oct; 19(5):256-264.
  5. Meireles SS, Heckmann SS, Leida FL, dos Santos Ida S, Della Bona A, Demarco FF. Efficacy and safety of 10% and 16% carbamide peroxide tooth-whitening gels: a randomized clinical trial. Oper Dent 2008 Nov-Dec; 33(6):606-612.
  6. Basting RT, Amaral FLB, França FMG, Flório FM. Clinical comparative study of the effectiveness of and tooth sensitivity to 10% and 20% carbamide peroxide home-use and 35% and 38% hydrogen peroxide in-office bleaching materials containing desensitizing agents. Oper Dent 2012 Sep-Oct; 37(5):464-473.
  7. Demarco FF, Meireles SS, Sarmento HR, Dantas RVF, Botero T, Tarquinio SBC. Erosion and abrasion on dental structures undergoing at-home bleaching. Clin Cosmet Investig Dent 2011 Jul; 18(3):45-52.
  8. Rezende M, Loguercio AD, Reis A, Kossatz S. Clinical effects of exposure to coffee during at-home vital bleaching. Oper Dent 2013 Nov-Dec; 38(6):E229-E236.
  9. Hyland BW, McDonald A, Lewis N, Tredwin C, Petrie A, Hall S, Callan JF. A new three-component formulation for the efficient whitening of teeth (Carbamide Plus). Clin Oral Investig 2015 Jul; 19(6):1395-1404.
  10. Almeida LC, Soares DG, Azevedo FA, Gallinari MD, Costa CA, Santos PH, Briso AL At-Home Bleaching: Color Alteration, Hydrogen Peroxide Diffusion and Cytotoxicity. Braz Dent J 2015 Jul-Aug; 26(4):378-383.
  11. De Geus JL, Bersezio C, Urrutia J, Yamada T, Fernández E, Loguercio AD, Reis A, Kossatz S. Effectiveness of and tooth sensitivity with at-home bleaching in smokers: A multicenter clinical trial. J Am Dent Assoc 2015 Apr; 146(4):233-240.
  12. Al-Qunaian TA, Matis BA, Cochran MA. In vivo kinetics of bleaching gel with three-percent hydrogen peroxide within the first hour. Oper Dent 2003 May-Jun; 28(3):236-241.
  13. Hanks CT, Fat JC, Wataha JC, Corcoran JF. Cytotoxicity and dentin permeability of carbamide peroxide and hydrogen peroxide vital bleaching materials, in vitro. J Dent Res 1993 May; 72(5):931-938.
  14. Oliver TL, Haywood VB. Efficacy of nightguard vital bleaching technique beyond the borders of a shortened tray. J Esthet Dent 1999; 11(2):95-102.
  15. Myers ML, Browning WD, Downey MC, Hackman ST. Clinical Evaluation of a 3% Hydrogen Peroxide Tooth Whitening Gel. J Esthet Restor Dent 2003 Jan; 15(1), 50-55. 16 Schulz KF, Altman DG, Moher D, CONSORT Group. CONSORT 2010 Statement: Updated guidelines for reporting parallel group randomised trials. Int J Surg. 2011 Oct; 9(8):672-677.
  16. Papas AS, Kugel G, Singh M, Barker ML, Gerlach RW. Placebo-controlled clinical trial of use of 10% hydrogen peroxide whitening strips for medication-induced xerostomia. Gerontology. 2009 Aug; 55(5):511-516.
  17. Alonso de la Peña V, López Ratón M. Randomized clinical trial on the efficacy and safety of four professional at-home tooth whitening gels. Oper Dent 2014 Mar-Apr; 39(2):136-143.
  18. Martín J, Vildósola P, Bersezio C, Herrera A, Bortolatto J, Saad JRC, Fernández E. Effectiveness of 6% hydrogen peroxide concentration for tooth bleaching - A double-blind, randomized clinical trial. J Dent 2015 Aug; 43(8):965-972.
  19. Da Costa JB, McPharlin R, Hilton T, Ferracane JL, Wang M. Comparison of two at-home whitening products of similar peroxide concentration and different delivery methods. Oper Dent 2012 Jul-Aug; 37(4):333-339.
  20. Rezende M, Bonafe E, Vochikovski L, Farago PV, Loguercio AD, Reis A, Kossatz S. Pre- and postoperative dexamethasone does not reduce bleaching-induced tooth sensitivity: A randomized, triple-masked clinical trial. J Am Dent Assoc 2016 Jan;147(1):41-49.
  21. Bernardon JK, Sartori N, Ballarin A, Perdigão J, Lopes GC, Baratieri LN. Clinical performance of vital bleaching techniques. Oper Dent 2010 Jan-Feb; 35(1):3-10.
  22. De l'Eclairage CI. Recommendations on uniform color spaces, color-difference equations, psychometric color terms. Paris: CIE. 1978.
  23. Dawson PF, Sharif MO, Smith AB, Brunton PA. A clinical study comparing the efficacy and sensitivity of home vs combined whitening. Oper Dent 2011 Sep-Oct; 36(5):460-466.
  24. Ghalili KM, Khawaled K, Rozen D, Afsahi V. Clinical study of the safety and effectiveness of a novel over-the-counter bleaching tray system. Clin Cosmet Investig Dent 2014 Feb; 21(6):15-19.
  25. Delgado E, Hernández-Cott PL, Stewart B, Collins M, De Vizio W. Tooth-whitening efficacy of custom tray-delivered 9% hydrogen peroxide and 20% carbamide peroxide during daytime use: a 14-day clinical trial. P R Health Sci J. 2007 Dec; 26(4):367-372.
  26. Silva FM, Nacano LG, Pizi ECG. Clinical evaluation of two dental bleaching systems. ROBRAC 2012; 21(57):473-479.
  27. Zhao K, Zong L, Zhang Q, Att W. Clinical comparison between two bleaching techniques: a 180-day follow-up study. Quintessence Int 2013 Jul; 44(8):601-607.
  28. Sundfeld RH, Neto DS, Machado LS, de Oliveira FG, de Alexandre RS, Palo RM, Sundefeld MM. Dental bleaching with a 10% hydrogen peroxide product: A six-month clinical observation. Indian J Dent Res 2014 Jan-Feb; 25(1):4-8
  29. Cardoso PC, Reis A, Loguercio A, Vieira LC, Baratieri LN. Clinical effectiveness and tooth sensitivity associated with different bleaching times for a 10 percent carbamide peroxide gel. J Am Dent Assoc 2010 Oct; 141(10):1213-1220.
  30. Bizhang M, Chun YP, Damerau K, Singh P, Raab WH, Zimmer S. Comparative clinical study of the effectiveness of three different bleaching methods. Oper Dent 2009 Nov; 34(6):635-641.
  31. Parreiras SO, Vianna P, Kossatz S, Loguercio AD, Reis A. Effects of light activated in-office bleaching on permeability, microhardness, and mineral content of enamel. Oper Dent 2014 Sep/Oct; 39(5):E225-E223.
  32. De la Pena VA, Cabrita OB. Comparison of the clinical efficacy and safety of carbamide peroxide and hydrogen peroxide in at-home bleaching gels. Quintessence Int 2006 Jul/Aug; 37(7):551-556.
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.