The Journal of Contemporary Dental Practice

Register      Login

SEARCH WITHIN CONTENT

FIND ARTICLE

Volume / Issue

Online First

Archive
Related articles

VOLUME 20 , ISSUE 6 ( June, 2019 ) > List of Articles

ORIGINAL RESEARCH

Efficacy of Amorphous Calcium Phosphate (ACP) Containing Adhesive in Preventing Demineralization during Orthodontic Treatment, a Triple Blinded Randomized Clinical Trial (RCT)

Fahad Mohammed Alshammari, Jamal Al Sanea

Keywords : Amorphous calcium phosphate, Demineralization, Enamel

Citation Information : Alshammari FM, Sanea JA. Efficacy of Amorphous Calcium Phosphate (ACP) Containing Adhesive in Preventing Demineralization during Orthodontic Treatment, a Triple Blinded Randomized Clinical Trial (RCT). J Contemp Dent Pract 2019; 20 (6):727-731.

DOI: 10.5005/jp-journals-10024-2587

License: CC BY-NC 4.0

Published Online: 01-06-2019

Copyright Statement:  Copyright © 2019; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Aim: The present study was done to evaluate in vivo effects of an amorphous calcium phosphate (ACP) containing adhesive in reducing enamel demineralization during the early stage of fixed orthodontic treatment. Materials and methods: A triple blinded randomized clinical trial (RCT) was conducted to evaluate enamel demineralization on 255 anterior teeth in 23 patients over a period of 6 months. A split-mouth design was used; half of the anterior teeth were bonded with the ACP containing adhesive and the contralateral teeth received regular adhesive as a control. The enamel demineralization measurements were done at three different time intervals: immediately after bonding (T0), 1 month after bonding (T1), and 6 months after bonding (T2) using the DIAGNOdent device. Results: Significant enamel demineralization variations were determined among groups (p < 0.001). The ACP containing adhesive showed significantly lower enamel demineralization than control adhesive. Conclusion: The result of this study suggests a positive effect on the reduction of enamel demineralization when using ACP containing adhesives during orthodontic treatment over regular adhesive.


PDF Share
  1. Mitchell L. Decalcification during orthodontic treatment with fixed appliances – an overview. Br J Orthod 1992;19:199–205. DOI: 10.1179/bjo.19.3.199.
  2. Derks A, Katsaros C, et al. Caries-inhibiting effect of preventive measures during orthodontic treatment with fixed appliances. A systematic review. Caries Res 2004;38:413–420. DOI: 10.1159/000079621.
  3. Fornell AC, Skold-Larsson K, et al. Effect of a hydrophobic tooth coating on gingival health, mutans streptococci, and enamel demineralization in adolescents with fixed orthodontic appliances. Acta Odontol Scand 2002;60:37–41. DOI: 10.1080/000163502753471989.
  4. O'Reilly MM, Featherstone JD. Demineralization and remineralization around orthodontic appliances: an in vivo study. Am J Orthod Dentofacial Orthop 1987;92:33–40. DOI: 10.1016/0889-5406(87)90293-9.
  5. Gorelick L, Geiger AM, et al. Incidence of white spot formation after bonding and banding. Am J Orthod 1982;81:93–98. DOI: 10.1016/0002-9416(82)90032-x.
  6. Lovrov S, Hertrich K, et al. Enamel demineralization during fixed orthodontic treatment-incidence and correlation to various oral-hygiene parameters. J Orofac Orthop 2007;68:353–363. DOI: 10.1007/s00056-007-0714-1.
  7. Uysal T, Amasyali M, et al. Efficiency of amorphous calcium phosphate-containing orthodontic composite and resin modified glass ionomer on demineralization evaluated by a new laser fluorescence device. Eur J Dent 2009;3:127–134.
  8. Mizrahi E. Enamel demineralization following orthodontic treatment. Am J Orthod 1982;82:62–67. DOI: 10.1016/0002-9416(82)90548-6.
  9. Ogaard B, Rolla G, et al. Orthodontic appliances and enamel demineralization. Part 1. Lesion development. Am J Orthod Dentofacial Orthop 1988a;94:68–73. DOI: 10.1016/0889-5406(88)90453-2.
  10. Boskey AL. Amorphous calcium phosphate: the contention of bone. J Dent Res 1997;76:1433–1436. DOI: 10.1177/00220345970760080501.
  11. Cross KJ, Huq NL, et al. NMR studies of a novel calcium, phosphate and fluoride delivery vehicle-alpha(S1)-casein(59-79)by stabilized amorphous calcium fluoride phosphate nano complexes. Biomaterials 2004;25:5061–5069. DOI: 10.1016/j.biomaterials.2004.01.045.
  12. Langhorst SE, O'donnell JN, et al. In vitro remineralization of enamel by polymermorphous calcium phosphate composite: quantitative micro radiographic study. Dent Mater 2009;25:884–891. DOI: 10.1016/j.dental.2009.01.094.
  13. Uysal T, Amasyali M, et al. Amorphous calcium phosphate containing orthodontic composites. Do they prevent demineralization around orthodontic brackets? Aust Orthod J 2010a;26:10–15.
  14. Chow CK, Wu CD, et al. In vitro properties of orthodontic adhesives with fluoride amorphous calciumphosphate. Int J Dent 2011;583521.
  15. Zachrisson BU, Brobakken BO. Clinical comparison of direct versus indirect bonding with different bracket types and adhesives. Am J Orthod 1978;74:62–78.
  16. Shen P, Cai F, et al. Remineralization of enamel subsurface lesions by sugar-free chewing gum containing casein phosphopeptideamorphous calcium phosphate. J Dent Res 2001;80:2066–2070. DOI: 10.1177/00220345010800120801.
  17. Reynolds EC, Cai F, et al. Retention in plaque and remineralization of enamel lesions by various forms of calcium in a mouthrinse or sugar-free chewing gum. J Dent Res 2003;82:206–211. DOI: 10.1177/154405910308200311.
  18. Uysal T, Amasyali M, et al. In vivo effects of amorphous calcium phosphate-containing orthodontic composite on enamel demineralization around orthodontic brackets. Aust Dent J 2010b;55:285–291. DOI: 10.1111/j.1834-7819.2010.01236.x.
  19. Behnan SM, Arruda AO, et al. In vitro evaluation of various treatments to prevent demineralization next to orthodontic brackets. Am J Orthod Dentofacial Orthop 2010;138:712e1–712e7. DOI: 10.1016/j. ajodo.2010.05.014.
  20. Richards N, Flaim GM, et al. Flexural strength and ion release of remineralizing resin restorative materials. J Dent Res 2007;86:2027.
  21. Sukontapatipark W, El Agroudi MA, et al. Bacterial colonization associated with fixed orthodontic appliances. A scanning electron microscopy study. Eur J Orthod 2001;23:475–484. DOI: 10.1093/ejo/23.5.475.
  22. Mizrahi E. Surface distribution of enamel opacities following orthodontic treatment. Am J Orthod 1983;84:323–331. DOI: 10.1016/s0002-9416(83)90348-2.
  23. Artun J, Brobakken BO. Prevalence of carious white spots after orthodontic treatment with multibonded appliances. Eur J Orthod 1986;8:229–234. DOI: 10.1093/ejo/8.4.229
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.