Aim and objective: The present study evaluated the effects of erbium, chromium:yttrium-scandium-gallium-garnet (Er,Cr:YSGG) laser on the weight percentage of mineral content of enamel when etched at three different power settings. Materials and methods: Total 20 extracted molar teeth were taken as samples. Enamel slabs were prepared by sectioning the crown from the buccal and lingual aspect with a double-sided diamond disk at slow speed. The 40 specimens were divided into four groups, i.e., control, 1 W, 2 W, and 3 W of 10 specimens each and then irradiation by Er,Cr:YSGG was done. The elements evaluated were calcium (Ca), potassium (K), magnesium (Mg), sodium (Na), and phosphorus (P). The mean weights of these minerals and the Ca:P ratio in each slab were measured by energy-dispersive X-ray spectroscopy analysis (EDAX). One-way analysis of variance (ANOVA) followed by the Turkey\'s test was performed with the help of critical difference (CD) or least significant difference (LSD) at 5 and 1% level of significance. Results: There was no significant differences among the four groups for the five minerals and for the calcium:phosphorous ratio (p > 0.05). Photomicrographs by scanning electron microscopy observations revealed that the surfaces exposed to a 3 watt irradiation showed more roughness than those of the 1 watt and 2 watt groups. Conclusion: The Er,Cr:YSGG irradiation of enamel at 1 W, 2 W, and 3 W had no significant effect on the mean percentage weights of Ca, K, Mg, Na, and P or the Ca/P ratio in any group. Clinical significance: Constriction with conviction is the new motto of restorative dentistry. Er,Cr:YSGG not only fulfills the aim but also is proving to alter the surface properties by recrystallization and change in composition making the prepared surface caries resistant.
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