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VOLUME 21 , ISSUE 4 ( April, 2020 ) > List of Articles

ORIGINAL RESEARCH

Gingival Crevicular Blood Glucose Levels. Is it a Reliable Tool for Screening Diabetes in a Dental Office?

Abhijeet R Sande, Sanjeela Guru, Rakshith Guru, Satish Gaduputi, Divya K Thati, Srinivasa T Siddeshappa

Keywords : Gingival crevicular blood, Glucometer, Glucose oxidase

Citation Information : Sande AR, Guru S, Guru R, Gaduputi S, Thati DK, Siddeshappa ST. Gingival Crevicular Blood Glucose Levels. Is it a Reliable Tool for Screening Diabetes in a Dental Office?. J Contemp Dent Pract 2020; 21 (4):421-425.

DOI: 10.5005/jp-journals-10024-2752

License: CC BY-NC 4.0

Published Online: 01-04-2020

Copyright Statement:  Copyright © 2020; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Aim: Periodontal disease is associated with gingival bleeding. Thus, the present study was aimed towards evaluating, whether the blood oozing during routine periodontal examination can be used for evaluating blood glucose levels. Materials and methods: A total of 100 patients reporting to Department of Oral Medicine and Radiology, within the age group of 25–55 years were enrolled. In fasting condition, gingival crevicular blood (GCB), finger-stick blood (FSB) was measured using a glucometer and venous blood (VB) glucose values were measured in the laboratory with glucose oxidase method. All the parameters thus recorded were then subjected to statistical analysis. Results: When compared, the GCB glucose values, VB glucose values and the FSB glucose values measured with glucometer in the diabetic and nondiabetic group were found to be highly statistically significant (p = 0.000). Conclusion: Gingival crevicular blood collected during diagnostic periodontal examination can provide a valid and acceptable source for measuring blood glucose levels using a glucometer. In addition, the technique described is quick, safe, easy to perform and more acceptable to the patients. Clinical significance: Dental surgeon can play an active role in screening of patients for glucose levels during routine periodontal examination and help to increase the frequency of diabetes screening in dental offices especially in undiagnosed diabetic cases which can be referred to the physician for appropriate management of the condition.


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  1. Manski RJ, Hoffmann D, Rowthorn V. Increasing access to dental and medical care by allowing greater flexibility in scope of practice. Am J Public Health 2015;105(9):1755–1762. DOI: 10.2105/AJPH.2015.302654.
  2. Wild S, Roglic G, Green A, et al. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 2004;27(5):1047–1053. DOI: 10.2337/diacare.27.5.1047.
  3. Chentli F, Azzoug S, Mahgoun S. Diabetes mellitus in elderly. Indian J Endocrinol Metab 2015;19(6):744–752. DOI: 10.4103/2230-8210.167553.
  4. Sibyl S, Bennadi D, Kshetrimayum N, et al. Correlations between gingival crevicular blood glucose and capillary blood glucose: a preliminary report. J Lab Physicians 2017;9(4):260–263. DOI: 10.4103/JLP.JLP_141_16.
  5. Debnath P, Govila V, Sharma M, et al. Glucometric assessment of gingival crevicular blood in diabetic and non-diabetic patients: a randomized clinical trial. J Oral Biol Craniofac Res 2015;5(1):2–6. DOI: 10.1016/j.jobcr.2014.12.004.
  6. Rajesh KS, Irshana R, Arun Kumar MS, et al. Effectiveness of glucometer in screening diabetes mellitus using gingival crevicular blood. Contemp Clin Dent 2016;7(2):182–185. DOI: 10.4103/0976-237X.183072.
  7. Shetty N, Shankarapillai R, Mathur LK, et al. Gingival crevicular blood: as a non-invasive screening tool for diabetes mellitus in dental clinics. J Indian Soc Periodontol 2013;17(4):472–477. DOI: 10.4103/0972-124X.118319.
  8. Ginsberg BH. Factors affecting blood glucose monitoring: sources of errors in measurement. J Diabetes Sci Technol 2009;3(4):903–913. DOI: 10.1177/193229680900300438.
  9. Preshaw PM, Bissett SM. Periodontitis: oral complication of diabetes. Endocrinol Metab Clin North Am 2013;42(4):849–867. DOI: 10.1016/j.ecl.2013.05.012.
  10. Chang PC, Lim LP. Interrelationships of periodontitis and diabetes: a review of the current literature. J Dent Sci 2012;7(3):272–282. DOI: 10.1016/j.jds.2012.02.002.
  11. Preshaw PM, Alba AL, Herrera D, et al. Periodontitis and diabetes: a two-way relationship. Diabetologia 2012;55(1):21–31. DOI: 10.1007/s00125-011-2342-y.
  12. Chopra P, Kumar T. Correlation of glucose level among venous, gingival and finger-prick blood samples in diabetic patients. J Indian Soc Periodontol 2011;15(3):288–291. DOI: 10.4103/0972-124X.85678.
  13. Parker RC, Rapley JW, Isley W, et al. Gingival crevicular blood for assessment of blood glucose in diabetic patient. J Periodontol 1993;64(7):666–672. DOI: 10.1902/jop.1993.64.7.666.
  14. Tsutsui P, Rich SK, Schonfeld SE. Reliability of intraoral blood for diabetes screening. J Oral Med 1985;40(2):62–66.
  15. Yared Z, Aljaberi K, Renouf N, et al. The effect of blood sample Volume on 11 glucose monitoring systems. Diabetes Care 2005;28(7): 1836–1837. DOI: 10.2337/diacare.28.7.1836.
  16. Parihar S, Tripathi R, Parihar AV, et al. Estimation of gingival crevicular blood glucose level for the screening of diabetes mellitus: a simple yet reliable method. J Oral Biol Craniofac Res 2016;6(3):198–203. DOI: 10.1016/j.jobcr.2016.05.004.
  17. Bhavsar MV, Brahmbhatt NA, Sahayata V, et al. Gingival crevicular blood for screening of blood glucose level in patients with and without diabetes: a chair-side test. Int J Dent Hyg 2016;14(2):92–97. DOI: 10.1111/idh.12139.
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