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VOLUME 21 , ISSUE 4 ( April, 2020 ) > List of Articles

ORIGINAL RESEARCH

Photobiomodulation Effect of Low-level Laser Therapy as a Palliative Treatment of Symptomatic Geographic Tongue (A Double-blinded Randomized Clinical Trial)

Islam Saad

Keywords : Geographic tongue, Low-level laser therapy, Photobiomodulation

Citation Information : Saad I. Photobiomodulation Effect of Low-level Laser Therapy as a Palliative Treatment of Symptomatic Geographic Tongue (A Double-blinded Randomized Clinical Trial). J Contemp Dent Pract 2020; 21 (4):453-457.

DOI: 10.5005/jp-journals-10024-2802

License: CC BY-NC 4.0

Published Online: 00-04-2020

Copyright Statement:  Copyright © 2020; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Aim: To evaluate the effectiveness of photobiomodulation (PBM) of low-level laser therapy (LLLT) as a palliative treatment of symptomatic geographic tongue. Materials and materials: This randomized double-blinded controlled clinical trial was performed on 50 patients with symptomatic geographic tongue (GT). Participants were allocated randomly into study and control groups. A 660-nm diode laser was applied on randomly selected patients of the study group (n = 25) over the complained site for 2 minutes with continuous laser beam application. For the control group (n = 25), no application of 660-nm diode laser was performed. None of the participants were aware if they received the LLLT or placebo treatment. Patients were assessed for the level of pain, burning sensation, and size of the lesion before starting LLLT “T0” and during recall visit “T1, T2, and T3.” Results: The study group showed a low level of pain, burning sensation, and better healing with statistically significant differences at T2 and T3 of the follow-up period, with a level of significance was set at p < 0.05. Conclusion: Low-level laser therapy can be used to adequately relieve significant discomforts associated with GT and accelerate healing and restoring of the patient’s quality of life. Clinical significance: To develop a framework based on the results regarding the photobiomodulation effect of a 660-nm diode laser to relieve pain and burning sensation associated with symptomatic GT, which increases patients’ perception toward the services provided to them.


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  1. Najafi S, Gholizadeh N, Akhavan Rezayat E, et al. Treatment of symptomatic geographic tongue with triamcinolone acetonide alone and in combination with retinoic acid: a randomized clinical trial. J Dent Tehran Iran 2016;13(1):23–28.
  2. de Campos WG, Esteves CV, Fernandes LG, et al. Treatment of symptomatic benign migratory glossitis: a systematic review. Clin Oral Investig 2018;22(7):2487–2493. DOI: 10.1007/s00784-018-2553-4.
  3. Burket LW, Greenberg MS, Glick M. Burket’s oral medicine: diagnosis and treatment. BC Decker; 2003.
  4. Barton DH, Spier S, Crovello TJ. Benign migratory glossitis and allergy. Pediatr Dent 1982;4(3):249–250.
  5. Shobha BV, Barkha N. Benign migratory glossitis: report of two cases [internet]. Indian J Dent Advance 2011. [cited 2019 Dec 6]. Available from https://link.galegroup.com/apps/doc/A310741333/AONE?sid=lms.
  6. Purani JM, Purani HJ. Treatment of geographic tongue with topical tacrolimus. Case Rep 2014;2014(1):bcr2013201268. DOI: 10.1136/bcr-2013-201268.
  7. Helfman RJ. The treatment of geographic tongue with topical Retin-A solution. Cutis 1979;24(2):179–180.
  8. Sigal MJ, Mock D. Symptomatic benign migratory glossitis: report of two cases and literature review. Pediatr Dent 1992;14(6):392–396.
  9. Vahedi M, Abdolsamadi HR, Mortazavi H, et al. Evaluation of the therapeutic effects of zinc sulfate in patients with geographic tongue. Avicenna J Dent Res 2009;1(1):11–14.
  10. Hooda A, Rathee M, Gulia J, et al. Benign migratory glossitis: a review. Internet J Fam Pr 2011;9(2):1.
  11. Abe M, Sogabe Y, Syuto T, et al. Successful treatment with cyclosporine administration for persistent benign migratory glossitis. J Dermatol 2007;34(5):340–343. DOI: 10.1111/j.1346-8138.2007.00284.x.
  12. Ishibashi M, Tojo G, Watanabe M, et al. Geographic tongue treated with topical tacrolimus. J Dermatol Case Rep 2010;4(4):57–59. DOI: 10.3315/jdcr.2010.1058.
  13. Saad I, Salem S. Evaluation of serum desmoglein 1 and desmoglein 3 in oral erosive lichen planus before and after topical application of tacrolimus. J Contemp Dent Pract 2018;19(10):1204–1213. DOI: 10.5005/jp-journals-10024-2406.
  14. Tafur J, Mills PJ. Low-intensity light therapy: exploring the role of redox mechanisms. Photomed Laser Surg 2008;26(4):323–328. DOI: 10.1089/pho.2007.2184.
  15. Karu T. Low power laser therapy, In: Vo-Dinh T, ed. Biomedical photonics handbook. ch. 48, UK: CRC Press Taylor Francis Group; 2003.
  16. Karu TI, Kolyakov SF. Exact action spectra for cellular responses relevant to phototherapy. Photomed Laser Surg 2005;23(4):355–361. DOI: 10.1089/pho.2005.23.355.
  17. Avci P, Gupta A, Sadasivam M, et al. Low-level laser (light) therapy (LLLT) in skin: stimulating, healing, restoring. Semin Cutan Med Surg 2013;32(1):41–52.
  18. Chung H, Dai T, Sharma SK, et al. The nuts and bolts of low-level laser (light) therapy. Ann Biomed Eng 2012;40(2):516–533. DOI: 10.1007/s10439-011-0454-7.
  19. Huskisson EC, Jones J, Scott PJ. Application of visual-analogue scales to the measurement of functional capacity. Rheumatology 1976;15(3):185–187. DOI: 10.1093/rheumatology/15.3.185.
  20. Jainkittivong A, Langlais RP. Geographic tongue: clinical characteristics of 188 cases. J Contemp Dent Pract 2005;6(1):123–135. DOI: 10.5005/jcdp-6-1-123.
  21. Assimakopoulos D, Patrikakos G, Fotika C, et al. Benign migratory glossitis or geographic tongue: an enigmatic oral lesion. Am J Med 2002;113(9):751–755. DOI: 10.1016/s0002-9343(02)01379-7.
  22. Picciani BLS, Domingos TA, Teixeira-Souza T, et al. Geographic tongue and psoriasis: clinical, histopathological, immunohistochemical and genetic correlation - a literature review. An Bras Dermatol 2016;91(4):410–421. DOI: 10.1590/abd1806-4841.20164288.
  23. Picciani B, Santos V, de C, et al. Investigation of the clinical features of geographic tongue: unveiling its relationship with oral psoriasis. Int J Dermatol 2017;56(4):421–427. DOI: 10.1111/ijd.13460.
  24. Izahias L, Souza T, Curty Á, et al. Investigation of clinical features of geographic tongue: unveiling its relationship with oral psoriasis. Oral Surg Oral Med Oral Pathol Oral Radiol [Internet] 2018;126(3):e183, Available from insights.ovid.com.
  25. Miloğlu Ö, Göregen M, Akgül HM, et al. The prevalence and risk factors associated with benign migratory glossitis lesions in 7619 Turkish dental outpatients. Oral Surg Oral Med Oral Pathol Oral Radiol Endodontology 2009;107(2):e29–e33. DOI: 10.1016/j.tripleo.2008.10.015.
  26. Honarmand M, Mollashahi LF, Shirzaiy M, et al. Geographic tongue and associated risk factors among Iranian dental patients. Iran J Public Health 2013;42(2):215.
  27. Salem S. Consequences of 660 nM diode laser following postsurgical exodontia in patients under contraceptive pills: a randomized double blinded clinical trial. J Contemp Dent Pract 2020;21(1):2–10. DOI: 10.5005/jp-journals-10024-2736.
  28. Silveira PCL, Silva LA, da, Fraga DB, et al. Evaluation of mitochondrial respiratory chain activity in muscle healing by low-level laser therapy. J Photochem Photobiol B 2009;95(2):89–92. DOI: 10.1016/j.jphotobiol.2009.01.004.
  29. Casu C, Bevilacqua P, Viganò L. Use of 808 NM diode laser for the treatment of geographic tongue 2017.
  30. Rocha Júnior AM, Vieira BJ, Andrade LCF, et al. Effects of low-level laser therapy on the progress of wound healing in humans: the contribution of in vitro and in vivo experimental studies. J Vasc Bras 2007;6(3):257–265. DOI: 10.1590/S1677-54492007000300009.
  31. Smith KC. Laser (and LED) therapy is phototherapy. Photomed Laser Ther 2005;23(1):78–80. DOI: 10.1089/pho.2005.23.78.
  32. Walsh LJ. The current status of low level laser therapy in dentistry, part 1. soft tissue applications. Aust Dent J 1997;42(4):247–254. DOI: 10.1111/j.1834-7819.1997.tb00129.x.
  33. Laakso L, Richardson C, Cramond T. Factors affecting low level laser therapy. Aust J Physiother 1993;39(2):95–99. DOI: 10.1016/S0004-9514(14)60473-6.
  34. Yu W, Naim JO, Lanzafame RJ. The effect of laser irradiation on the release of BFGF from 3T3 fibroblasts. Photochem Photobiol 1994;59(2):167–170. DOI: 10.1111/j.1751-1097.1994.tb05017.x.
  35. Aggarwal H, Singh MP, Nahar P, et al. Efficacy of low-level laser therapy in treatment of recurrent aphthous ulcers – a sham controlled, split mouth follow up study. J Clin Diagn Res JCDR 2014;8(2):218–221. DOI: 10.7860/JCDR/2014/7639.4064.
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