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VOLUME 21 , ISSUE 5 ( May, 2020 ) > List of Articles

ORIGINAL RESEARCH

Antifungal Activity of Peruvian Banana Peel (Musa paradisiaca L.) on Candida albicans: An In Vitro Study

Monica Loyaga-Castillo, Roger D Calla-Poma, Rubén Calla-Poma, Margarita F Requena-Mendizabal, Pablo A Millones-Gómez

Keywords : Antifungal, Banana, Candida albicans, Hydroethanolic extract, Musa × paradisiaca, Oral candidiasis

Citation Information : Loyaga-Castillo M, Calla-Poma RD, Calla-Poma R, Requena-Mendizabal MF, Millones-Gómez PA. Antifungal Activity of Peruvian Banana Peel (Musa paradisiaca L.) on Candida albicans: An In Vitro Study. J Contemp Dent Pract 2020; 21 (5):509-514.

DOI: 10.5005/jp-journals-10024-2827

License: CC BY-NC 4.0

Published Online: 30-05-2020

Copyright Statement:  Copyright © 2020; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Aim: The purpose of this study was to compare the antifungal activity of three concentrations of a hydroethanolic extract of the Musa × paradisiaca peel against Candida albicans strain ATCC 10231. Materials and methods: The agar diffusion method was used, and the culture medium used was Sabouraud agar. Petri dishes were prepared with concentrations of 10, 30, and 50% of hydroethanolic extract of the M. × paradisiaca peel; nystatin was used as a positive control, and 96% ethanol was used as a negative control. After 24 hours of incubation, each plate was examined, and the diameters (mm) of the growth inhibition halos were measured around each well using a digital vernier caliper. Results: The results showed that the antifungal activity of the extract varied, depending on the concentration, as shown using analysis of variance (ANOVA; p < 0.05). When comparing the different concentrations, it was found by Duncan test that the greatest activity was obtained at 50%. Conclusion: It was concluded that the hydroethanolic extract of M. × paradisiaca at 50% exerted a greater antifungal effect on the strain of C. albicans than did the extract at lower concentrations. Clinical significance: By knowing the antimicrobial effect of M. × paradisiaca, this substance can be effectively used in products aimed to cure candidiasis infection.


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