Citation Information :
Najafi HZ, Azadeh N, Motamedifar M. Evaluation of the Preventive Effect of Composites Containing Silver and TiO2 Nanoparticles on Demineralization around Orthodontic Brackets. J Contemp Dent Pract 2020; 21 (8):874-879.
Aim: The aim of this study was to investigate the antidemineralization effect of composites containing silver and titanium dioxide (TiO2) nanoparticles used for bonding brackets to tooth specimens. Materials and methods: A total of 75 freshly extracted teeth were etched and primed and then randomly assigned to three adhesive groups: (1) conventional orthodontic adhesive, (2) conventional adhesive mixed with TiO2 nanoparticles, and (3) conventional adhesive mixed with silver nanoparticles. In each group, brackets were bonded with the pertinent adhesive. Teeth were painted with varnish on all surfaces except a 2-mm rim around brackets. Specimens were subjected to a cariogenic process in a circulating microbial model inoculated with Streptococcus mutans and Lactobacillus casei for 12 days and subsequently sectioned for cross-sectional microhardness testing. In each specimen, enamel microhardness was determined in three locations: 25–30 μm and 1.5 mm away from the bracket and under the varnish-protected enamel. Hardness of enamel in the first two locations was reported as a percentage of the protected enamel hardness. Results: Enamel hardness was higher at 25–30 μm away from brackets in both the experimental groups (p value < 0.05), and the nanoparticles acted similarly in this location (p value = 0.992). At 1.5 mm away from the brackets, there was no difference between experimental and control groups (p value > 0.05); the effect of TiO2 attenuated in this location while silver remained as potent. Conclusion: Both nanoparticles resulted in decreased demineralization at 25–30 μm from the bracket but farther away the effect of TiO2 was diminished. Clinical significance: According to the results of this study, composites containing silver and TiO2 nanoparticles can be suggested as anti-demineralization adhesives in case their biocompatibility is proved.
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