COVID-19 and Dentistry: An Updated Overview of Dental Perspectives and a Recommended Protocol for Dental Care and Emergency Dental Treatment
Mahmoud K AL-Omiri, Mohammad H Al-Shayyab, Abdullah A Al Nazeh, Islam A Alraheam, Ziad A Malkawi, Abdallah K Alomiri, Ibrahim A Alzoubi, Edward Lynch
Aerosol, COVID-19, Dental care, Personal protective equipment, SARS-CoV-2, Viral transmission
Citation Information :
AL-Omiri MK, Al-Shayyab MH, Al Nazeh AA, Alraheam IA, Malkawi ZA, Alomiri AK, Alzoubi IA, Lynch E. COVID-19 and Dentistry: An Updated Overview of Dental Perspectives and a Recommended Protocol for Dental Care and Emergency Dental Treatment. J Contemp Dent Pract 2021; 22 (5):572-586.
Aim and objective: This manuscript aims to provide an overview of the coronavirus disease-2019 (COVID-19) pandemic from dental perspectives, and presents standards and guidelines of dental care provision based on available research in this field as well as clinical experience and practice.
Background: The current COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is spreading around the globe and interferes with the provision of dental care for many individuals from different communities and backgrounds. A search for the literature on PubMed, ISI Web of Science, Scopus, EMBASE, and Cochrane Library from March 1, 2020 to December 30, 2020 was conducted. Also, the bibliographies included in the indicated articles were used to identify further literature. Recommendations by health authorities in different countries were also consulted.
Results: COVID-19 is causing many fatalities and is disrupting people\'s daily life and the economy in many countries around the world. Due to the potential of cross-infection through dental treatments, especially dental aerosol generation procedures, the dental profession has been disrupted during this pandemic. Dental care provision has been ceased completely or partially (limited to emergency or urgent treatment) in most countries around the world. Until this pandemic is controlled by new suitable treatments and/or vaccination, there is an urgent need to adopt immediate guidelines and standards for the safe provision of dental care to meet patients’ demands, especially for the dental aerosols.
Conclusion: Guidelines and standards for dental treatment amidst the COVID-19 pandemic are required. This manuscript provides an overview of the COVID-19 pandemic from dental perspectives and presents standards and guidelines of dental care provision based on available research in this field as well as clinical experience and practice.
Clinical significance: This manuscript provides guidelines and standards for dental treatment and clinical management within dental settings amidst the COVID-19 pandemic, and resembles part of the quest to set the golden standards for dental care during the current circumstances.
Coronaviridae Study Group of the International Committee on Taxonomy of Viruses. The species severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2. Version 2. Nat Microbiol 2020;5(4):536–544. DOI: 10.1038/s41564-020-0695-z.
Liu J, Zheng X, Tong Q, et al. Overlapping and discrete aspects of the pathology and pathogenesis of the emerging human pathogenic coronaviruses SARS-CoV, MERS-CoV, and 2019-nCoV. J Med Virol 2020;92(5):491–494. DOI: 10.1002/jmv.25709.
Verity R, Okell LC, Dorigatti I, et al. Estimates of the severity of coronavirus disease 2019: a model-based analysis. Lancet Infect Dis 2020;20(6):669–677. DOI: 10.1016/S1473-3099(20)30243-7.
Wu Z, McGoogan JM. Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72314 cases from the Chinese Center for Disease Control and Prevention. JAMA 2020;323(13):1239–1242. DOI: 10.1001/jama.2020.2648.
Yu F, Du L, Ojcius DM, et al. Measures for diagnosing and treating infections by a novel coronavirus responsible for a pneumonia outbreak originating in Wuhan, China. Microbes Infect 2020;22(2):74–79. DOI: 10.1016/j.micinf.2020.01.003.
Zangrillo A, Beretta L, Scandroglio AM, et al. Characteristics, treatment, outcomes and cause of death of invasively ventilated patients with COVID-19 ARDS in Milan, Italy. Crit Care Resusc 2020;22(3):200–211.
Khailany RA, Safdar M, Ozaslan M. Genomic characterization of a novel SARS-CoV-2. Gene Rep 2020;19:100682. DOI: 10.1016/j.genrep.2020.100682.
Korber B, Fischer W, Gnanakaran S, et al. Tracking changes in SARS-CoV-2 spike: evidence that D614G increases infectivity of the COVID-19 virus. Cell 2020;182(4):812–827.e19. DOI: 10.1016/j.cell.2020.06.043.
Du W, Yu J, Wang H, et al. Clinical characteristics of Covid-19 in children compared with adults in Shandong Province, China. Infection 2020;48(3):445–452. DOI: 10.1007/s15010-020-01427-2.
Lechien JR, Chiesa-Estomba CM, Place S, et al. Clinical and epidemiological characteristics of 1420 European patients with mild-to-moderate coronavirus disease 2019. J Intern Med 2020;288(3):335–344. DOI: 10.1111/joim.13089.
Meng H, Xiong R, He R, et al. CT imaging and clinical course of asymptomatic cases with COVID-19 pneumonia at admission in Wuhan, China. J Infect 2020;81(1):e33–e39. DOI: 10.1016/j.jinf.2020.04.004.
Shi H, Han X, Jiang N, et al. Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study. Lancet Infect Dis 2020;20(4):425–434. DOI: 10.1016/S1473-3099(20)30086-4.
Fu L, Wang B, Yuan T, et al. Clinical characteristics of coronavirus disease 2019 (COVID-19) in China: a systematic review and meta-analysis. J Infect 2020;80(6):656–665. DOI: 10.1016/j.jinf.2020.03.041.
Han C, Duan C, Zhang S, et al. Digestive symptoms in COVID-19 patients with mild disease severity: clinical presentation, stool viral RNA testing, and outcomes. Am J Gastroenterol 2020;115(6):916–923. DOI: 10.14309/ajg.0000000000000664.
Mao L, Jin H, Wang M, et al. Neurological manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China: a retrospective case series study. JAMA Neurol 2020;77(6):683–690. DOI: 10.1001/jamaneurol.2020.1127.
Recalcati S. Cutaneous manifestations in COVID-19: a first perspective. J Eur Acad Dermatol Venereol 2020;34(5):e212–e213. DOI: 10.1111/jdv.16387.
Tu YF, Chien CS, Yarmishyn AA, et al. A review of SARS-CoV-2 and the ongoing clinical trials. Int J Mol Sci 2020;21(7):2657. DOI: 10.3390/ijms21072657.
Zheng F, Tang W, Li H, et al. Clinical characteristics of 161 cases of corona virus disease 2019 (COVID-19) in Changsha. Eur Rev Med Pharmacol Sci 2020;24(6):3404–3410. DOI: 10.26355/eurrev_202003_20711.
Zhu J, Ji P, Pang J, et al. Clinical characteristics of 3062 COVID-19 patients: a meta-analysis. J Med Virol 2020;92(10):1902–1914. DOI: 10.1002/jmv.25884.
Lan L, Xu D, Ye G, et al. Positive RT-PCR test results in patients recovered from COVID-19. JAMA 2020;323(15):1502–1503. DOI: 10.1001/jama.2020.2783.
Cai Q, Huang D, Ou P, et al. COVID-19 in a designated infectious diseases hospital outside Hubei Province, China. Allergy 2020;75(7):1742–1752. DOI: 10.1111/all.14309.
Feng Y, Ling Y, Bai T, et al. COVID-19 with different severity: a multi-center study of clinical features. Am J Respir Crit Care Med 2020;201(11):1380–1388. DOI: 10.1164/rccm.202002-0445OC.
Lippi G, Mattiuzzi C, Sanchis-Gomar F, et al. Clinical and demographic characteristics of patients dying from COVID-19 in Italy vs China. J Med Virol 2020;92(10):1759–1760.
Li X, Xu S, Yu M, et al. Risk factors for severity and mortality in adult COVID-19 inpatients in Wuhan. J Allergy Clin Immunol 2020;146(1):110–118. DOI: 10.1016/j.jaci.2020.04.006.
Mizumoto K, Kagaya K, Zarebski A, et al. Estimating the asymptomatic proportion of coronavirus disease 2019 (COVID-19) cases on board the Diamond Princess cruise ship, Yokohama, Japan, 2020. Euro Surveill 2020;25(10):2000180. DOI: 10.2807/1560-7917.ES.2020.25.10.2000180.
Zhang J, Litvinova M, Liang Y, et al. Changes in contact patterns shape the dynamics of the COVID-19 outbreak in China. Science 2020;368(6498):1481–1486. DOI: 10.1126/science.abb8001.
Fang Y, Nie Y, Penny M. Transmission dynamics of the COVID-19 outbreak and effectiveness of government interventions: a data-driven analysis. J Med Virol 2020;92(6):645–659. DOI: 10.1002/jmv.25750.
Wu J, Liu J, Li S, et al. Detection and analysis of nucleic acid in various biological samples of COVID-19 patients. Travel Med Infect Dis 2020;37:101673. DOI: 10.1016/j.tmaid.2020.101673.
Xiang F, Wang X, He X, et al. Antibody detection and dynamic characteristics in patients with coronavirus disease 2019. Clin Infect Dis 2020;71(8):1930–1934. DOI: 10.1093/cid/ciaa461.
Callaway E. The race for coronavirus vaccines: a graphical guide. Nature 2020;580(7805):576–577. DOI: 10.1038/d41586-020-01221-y.
Callaway E. Coronavirus vaccine trials have delivered their first results—but their promise is still unclear. Nature 2020;581(7809):363–364. DOI: 10.1038/d41586-020-01092-3.
Gao Q, Bao L, Mao H, et al. Rapid development of an inactivated vaccine candidate for SARS-CoV-2. Science 2020;369(6499):77–81. DOI: 10.1126/science.abc1932.
2019 novel coronavirus: implications for virus origins and receptor binding. Lancet 2020;395(10224):565–574. DOI: 10.1016/S0140-6736(20)30251-8.
Mehta N, Mazer-Amirshahi M, Alkindi N, et al. Pharmacotherapy in COVID-19; a narrative review for emergency providers. Am J Emerg Med 2020;38(7):1488–1493. DOI: 10.1016/j.ajem.2020.04.035.
Wang M, Cao R, Zhang L, et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res 2020;30(3):269–271. DOI: 10.1038/s41422-020-0282-0.
Yu J, Tostanoski LH, Peter L, et al. DNA vaccine protection against SARS-CoV-2 in rhesus macaques. Science 2020;369(6505):806–811. DOI: 10.1126/science.abc6284.
Kissler SM, Tedijanto C, Goldstein E, et al. Projecting the transmission dynamics of SARS-CoV-2 through the postpandemic period. Science 2020;368(6493):860–868. DOI: 10.1126/science.abb5793.
Kucharski AJ, Russell TW, Diamond C, et al. Early dynamics of transmission and control of COVID-19: a mathematical modelling study. Lancet Infect Dis 2020;20(5):553–558. DOI: 10.1016/S1473-3099(20)30144-4.
Lai CC, Liu YH, Wang CY, et al. Asymptomatic carrier state, acute respiratory disease, and pneumonia due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): facts and myths. J Microbiol Immunol Infect 2020;53(3):404–412. DOI: 10.1016/j.jmii.2020.02.012.
Zhang J, Litvinova M, Wang W, et al. Evolving epidemiology and transmission dynamics of coronavirus disease 2019 outside Hubei province, China: a descriptive and modelling study. Lancet Infect Dis 2020;20(7):793–802. DOI: 10.1016/S1473-3099(20)30230-9.
Izzetti R, Nisi M, Gabriele M, et al. COVID-19 transmission in dental practice: brief review of preventive measures in Italy. J Dent Res 2020;99(9):1030–1038. DOI: 10.1177/0022034520920580.
Meng L, Hua F, Bian Z. Coronavirus disease 2019 (COVID-19): emerging and future challenges for dental and oral medicine. J Dent Res 2020;99(5):481–487. DOI: 10.1177/0022034520914246.
Peng X, Xu X, Li Y, et al. Transmission routes of 2019-nCoV and controls in dental practice. Int J Oral Sci 2020;12(1):9. DOI: 10.1038/s41368-020-0075-9.
Thamboo A, Lea J, Sommer DD, et al. Clinical evidence based review and recommendations of aerosol generating medical procedures in otolaryngology—head and neck surgery during the COVID-19 pandemic. J Otolaryngol Head Neck Surg 2020;49(1):28. DOI: 10.1186/s40463-020-00425-6.
Guo H, Zhou Y, Liu X, et al. The impact of the COVID-19 epidemic on the utilization of emergency dental services. J Dent Sci 2020;15(4):564–567. DOI: 10.1016/j.jds.2020.02.002.
Yang Y, Zhou Y, Liu X, et al. Health services provision of 48 public tertiary dental hospitals during the COVID-19 epidemic in China. Clin Oral Investig 2020;24(5):1861–1864. DOI: 10.1007/s00784-020-03267-8.
Clarkson J, Ramsay C, Aceves M, et al. Recommendations for the re-opening of dental services: a rapid review of international sources, COVID-19 Dental Services Evidence Review (CoDER) Working Group, Version 1.3. Cochrane Oral Health 2020. Available online: https://oralhealth.cochrane.org/news/recommendations-re-opening-dental-services-rapid-review-international-sources (accessed on 7-11-2020).
COVID-19 Task Group, College of General Dentistry (CGDent) and Faculty of General Dental Practice (FGDP (UK)). Implications of COVID-19 for the safe management of general dental practice: a practical guide. 2020. Available online: https://www.fgdp.org.uk/implications-covid-19-safe-management-general-dental-practice-practical-guide (accessed on 7-11-2020).
Ministry of Health, Jordan, Press Release 2020. Available online: https://corona.moh.gov.jo/en/MediaCenter/ (accessed on 7-11-2020).
Li Q, Guan X, Wu P, et al. Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia. N Engl J Med 2020;382(13):1199–1207. DOI: 10.1056/NEJMoa2001316.
Sanche S, Lin YT, Xu C, et al. High contagiousness and rapid spread of severe acute respiratory syndrome coronavirus 2. Emerg Infect Dis 2020;26(7):1470–1477. DOI: 10.3201/eid2607.200282.
Zhao S, Lin Q, Ran J, et al. Preliminary estimation of the basic reproduction number of novel coronavirus (2019-nCoV) in China, from 2019 to 2020: a data-driven analysis in the early phase of the outbreak. Int J Infect Dis 2020;92:214–217. DOI: 10.1016/j.ijid.2020.01.050.
Cowling BJ, Ali ST, Ng TWY, et al. Impact assessment of non-pharmaceutical interventions against coronavirus disease 2019 and influenza in Hong Kong: an observational study. Lancet Public Health 2020;5(5):e279–e288. DOI: 10.1016/S2468-2667(20)30090-6.
Hellewell J, Abbott S, Gimma A, et al. Feasibility of controlling COVID-19 outbreaks by isolation of cases and contacts. Lancet Glob Health 2020;8(4):e488–e496. DOI: 10.1016/S2214-109X(20)30074-7.
Jin YH, Cai L, Cheng ZS, et al. A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version). Mil Med Res 2020;7(1):4. DOI: 10.1186/s40779-020-0233-6.
Guo YR, Cao QD, Hong ZS, et al. The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak—an update on the status. Mil Med Res 2020;7(1):11. DOI: 10.1186/s40779-020-00240-0.
Backer JA, Klinkenberg D, Wallinga J. Incubation period of 2019 novel coronavirus (2019-nCoV) infections among travellers from Wuhan, China, 20–28 January 2020. Euro Surveill 2020;25(5):2000062. DOI: 10.2807/1560-7917.ES.2020.25.5.2000062.
Chen D, Xu W, Lei Z, et al. Recurrence of positive SARS-CoV-2 RNA in COVID-19: a case report. Int J Infect Dis 2020;93:297–299. DOI: 10.1016/j.ijid.2020.03.003.
Fernandes Valente Takeda C, Moura de Almeida M, Gonçalves de Aguiar Gomes R, et al. Case report: recurrent clinical symptoms of COVID-19 in healthcare professionals: a series of cases from Brazil. Am J Trop Med Hyg 2020;103(5):1993–1996. DOI: 10.4269/ajtmh.20-0893.
To KK, Hung IF, Ip JD, et al. COVID-19 re-infection by a phylogenetically distinct SARS-coronavirus-2 strain confirmed by whole genome sequencing. Clin Infect Dis 2020;ciaa1275. DOI: 10.1093/cid/ciaa1275.
Xing Y, Mo P, Xiao Y, et al. Post-discharge surveillance and positive virus detection in two medical staff recovered from coronavirus disease 2019 (COVID-19), China, January to February 2020. Euro Surveill 2020;25(10):2000191. DOI: 10.2807/1560-7917.ES.2020.25.10.2000191.
Zhang B, Liu S, Dong Y, et al. Positive rectal swabs in young patients recovered from coronavirus disease 2019 (COVID-19). J Infect 2020;81(2):e49–e52. DOI: 10.1016/j.jinf.2020.04.023.
Zhang W, Du RH, Li B, et al. Molecular and serological investigation of 2019-nCoV infected patients: implication of multiple shedding routes. Emerg Microbes Infect 2020;9(1):386–389. DOI: 10.1080/22221751.2020.1729071.
Yu IT, Li Y, Wong TW, et al. Evidence of airborne transmission of the severe acute respiratory syndrome virus. N Engl J Med 2004;350(17):1731−1739. DOI: 10.1056/NEJMoa032867.
Otter JA, Donskey C, Yezli S, et al. Transmission of SARS and MERS coronaviruses and influenza virus in healthcare settings: the possible role of dry surface contamination. J Hosp Infect 2016;92(3):235–250. DOI: 10.1016/j.jhin.2015.08.027.
Lewis D. Is the coronavirus airborne? Experts can't agree. Nature 2020;580(7802):175. DOI: 10.1038/d41586-020-00974-w.
Lan J, Song Z, Miao X, et al. Skin damage and the risk of infection among health care workers managing coronavirus disease-2019. J Am Acad Dermatol 2020;82(5):1215–1216. DOI: 10.1016/j.jaad.2020.03.014.
Xie X, Li Y, Chwang AT, et al. How far droplets can move in indoor environments—revisiting the Wells evaporation-falling curve. Indoor Air 2007;17(3):211–225. DOI: 10.1111/j.1600-0668.2007.00469.x.
Leung NHL, Chu DKW, Shiu EYC, et al. Respiratory virus shedding in exhaled breath and efficacy of face masks. Nat Med 2020;26(5):676–680. DOI: 10.1038/s41591-020-0843-2.
Liu Y, Ning Z, Chen Y, et al. Aerodynamic analysis of SARS-CoV-2 in two Wuhan hospitals. Nature 2020;582(7813):557–560. DOI: 10.1038/s41586-020-2271-3.
Prather KA, Wang CC, Schooley RT. Reducing transmission of SARS-CoV-2. Science 2020;368(6498):1422–1424. DOI: 10.1126/science.abc6197.
Setti L, Passarini F, De Gennaro G, et al. Airborne transmission route of COVID-19: why 2 meters/6 feet of inter-personal distance could not be enough. Int J Environ Res Public Health 2020;17(8):2932. DOI: 10.3390/ijerph17082932.
Stadnytskyi V, Bax CE, Bax A, et al. The airborne lifetime of small speech droplets and their potential importance in SARS-CoV-2 transmission. Proc Natl Acad Sci U S A 2020;117(22):11875–11877. DOI: 10.1073/pnas.2006874117.
van Doremalen N, Bushmaker T, Morris DH, et al. Aerosol and surface stability of HCoV-19 (SARS-CoV-2) compared to SARS-CoV-1. N Engl J Med 2020;382(16):1564–1567. DOI: 10.1056/NEJMc2004973.
Tellier R, Li Y, Cowling BJ, et al. Recognition of aerosol transmission of infectious agents: a commentary. BMC Infect Dis 2019;19(1):101. DOI: 10.1186/s12879-019-3707-y.
Morawska L, Cao J. Airborne transmission of SARS-CoV-2: the world should face the reality. Environ Int 2020;139:105730. DOI: 10.1016/j.envint.2020.105730.
Buonanno G, Stabile L, Morawska L. Estimation of airborne viral emission: quanta emission rate of SARS-CoV-2 for infection risk assessment. Environ Int 2020;141:105794. DOI: 10.1016/j.envint.2020.105794.
Rothe C, Schunk M, Sothmann P, et al. Transmission of 2019-nCoV infection from an asymptomatic contact in Germany. N Engl J Med 2020;382(10): 970–971. DOI: 10.1056/NEJMc2001468.
To KK, Tsang OT, Leung WS, et al. Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study. Lancet Infect Dis 2020;20(5):565–574. DOI: 10.1016/S1473-3099(20)30196-1.
To KK, Tsang OT, Yip CY, et al. Consistent detection of 2019 novel coronavirus in saliva. Clin Infect Dis 2020;71(15):841–843. DOI: 10.1093/cid/ciaa149.
Wölfel R, Corman VM, Guggemos W, et al. Virological assessment of hospitalized patients with COVID-2019. Nature 2020;581(7809):465–469. DOI: 10.1038/s41586-020-2196-x.
Zou L, Ruan F, Huang M, et al. SARS-CoV-2 viral load in upper respiratory specimens of infected patients. N Engl J Med 2020;382(12):1177–1179. DOI: 10.1056/NEJMc2001737.
Xu H, Zhong L, Deng J, et al. High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa. Int Oral Sci 2020;12(1):8. DOI: 10.1038/s41368-020-0074-x.
Bennett AM, Fulford MR, Walker JT, et al. Microbial aerosols in general dental practice. Br Dent J 2000;189(12):664–667. DOI: 10.1038/sj.bdj.4800859.
Cellini L, Di Campli E, Di Candia M, et al. Quantitative microbial monitoring in a dental office. Public Health 2001;115(4):301–305. DOI: 10.1038/sj.ph.1900746.
Araujo MWB, Andreana S. Risk and prevention of infectious diseases in dentistry. Quintessence Int 2002;33(5):376–382.
Harrel SK, Molinari J. Aerosols and splatter in dentistry: a brief review of the literature and infection control implications. J Am Dent Assoc 2004;135(4):429–437. DOI: 10.14219/jada.archive.2004.0207.
Askarian M, Mirraei K, Honarvar B, et al. Knowledge, attitude and practice towards droplet and airborne isolation precautions among dental health care professionals in Shiraz, Iran. J Public Health Dent 2005;65(1):43–47. DOI: 10.1111/j.1752-7325.2005.tb02785.x.
Chen C, Zhao B, Cui W, et al. The effectiveness of an air cleaner in controlling droplet/aerosol particle dispersion emitted from a patient's mouth in the indoor environment of dental clinics. J R Soc Interface 2010;7(48):1105–1118. DOI: 10.1098/rsif.2009.0516.
Veena HR, Mahantesha S, Joseph PA, et al. Dissemination of aerosol and splatter during ultrasonic scaling: a pilot study. J Infect Public Health 2015;8(3):260–265. DOI: 10.1016/j.jiph.2014.11.004.
Watanabe A, Tamaki N, Yokota K, et al. Use of ATP bioluminescence to survey the spread of aerosol and splatter during dental treatments. J Hosp Infect 2018;99(3):303–305. DOI: 10.1016/j.jhin.2018.03.002.
Ge ZY, Yang LM, Xia JJ, et al. Possible aerosol transmission of COVID-19 and special precautions in dentistry. J Zhejiang Univ Sci B 2020;21(5):361–368. DOI: 10.1631/jzus.B2010010.
Yu J, Zhang T, Zhao D, et al. Characteristics of endodontic emergencies during coronavirus disease 2019 outbreak in Wuhan. J Endod 2020;46(6):730–735. DOI: 10.1016/j.joen.2020.04.001.
Estai M, Kanagasingam Y, Tennant M, et al. A systematic review of the research evidence for the benefits of teledentistry. J Telemed Telecare 2018;24(3):147–156. DOI: 10.1177/1357633X 16689433.
Ather A, Patel B, Ruparel NB, et al. Coronavirus disease 19 (COVID-19): implications for clinical dental care. J Endod 2020;46(5):584–595. DOI: 10.1016/j.joen.2020.03.008.
Baghizadeh Fini M. What dentists need to know about COVID-19. Oral Oncol 2020;105:104741. DOI: 10.1016/j.oraloncology.2020.104741.
Barabari P, Moharamzadeh K. Novel coronavirus (COVID-19) and dentistry—a comprehensive review of literature. Dent J (Basel) 2020;8(2):53. DOI: 10.3390/dj8020053.
Fallahi HR, Keyhan SO, Zandian D, et al. Being a front-line dentist during the Covid-19 pandemic: a literature review. Version 2. Maxillofac Plast Reconstr Surg 2020;42(1):12. DOI: 10.1186/s40902-020-00256-5.
Lee Y-L, Chu D, Chou S-Y, et al. Dental care and infection-control procedures during the COVID-19 pandemic: the experience in Taipei City Hospital, Taiwan. J Dent Sci 2020;15(3):369–372. DOI: 10.1016/j.jds.2020.05.011.
Lo Giudice R. The severe acute respiratory syndrome coronavirus-2 (SARS CoV-2) in dentistry. Management of biological risk in dental practice. Int J Environ Res Public Health 2020;17(9):3067. DOI: 10.3390/ijerph17093067.
Banakar M, Bagheri Lankarani K, Jafarpour D, et al. COVID-19 transmission risk and protective protocols in dentistry: a systematic review. BMC Oral Health 2020;20(1):275. DOI: 10.1186/s12903-020-01270-9.
Adawee MO, Brum RE, Ellsworth LJ. Examining common characteristics among healthcare personnel positive for COVID-19 and the effectiveness of healthcare personnel mask use in preventing COVID-19 in a large health system in Central Michigan. J Occup Environ Med 2021;63(3):226–229. DOI: 10.1097/JOM.0000000000002077.
Lelieveld J, Helleis F, Borrmann S, et al. Model calculations of aerosol transmission and infection risk of COVID-19 in indoor environments. Int J Environ Res Public Health 2020;17(21):8114. DOI: 10.3390/ijerph17218114.
Long Y, Hu T, Liu L, et al. Effectiveness of N95 respirators versus surgical masks against influenza: a systematic review and meta-analysis. J Evid Based Med 2020;13(2):93–101. DOI: 10.1111/jebm.12381.
Lee SA, Hwang DC, Li HY, et al. Particle size-selective assessment of protection of European Standard FFP respirators and surgical masks against particles-tested with human subjects. J Healthc Eng 2016;2016:8572493. DOI: 10.1155/2016/8572493.
Hirschmann MT, Hart A, Henckel J, et al. COVID-19 coronavirus: recommended personal protective equipment for the orthopaedic and trauma surgeon. Knee Surg Sports Traumatol Arthrosc 2020;28(6):1690–1698. DOI: 10.1007/s00167-020-06022-4.
Coulthard P. Dentistry and coronavirus (COVID-19)—moral decision-making. Br Dent J 2020;228(7):503–505. DOI: 10.1038/s41415-020-1482-1.
Sayburn A. Are UK doctors getting sufficient protective equipment against covid-19? BMJ 2020;369:m1297. DOI: 10.1136/bmj.m1297.
Douglas JDM, McLean N, Horsley C, et al. COVID-19: smoke testing of surgical mask and respirators. Occup Med (Lond) 2020;70(8):556–563. DOI: 10.1093/occmed/kqaa167.
Derrick JL, Gomersall CD. Protecting healthcare staff from severe acute respiratory syndrome: filtration capacity of multiple surgical masks. J Hosp Infect 2005;59(4):365–368. DOI: 10.1016/j.jhin.2004.10.013.
Kannan S, Shaik Syed Ali P, Sheeza A, et al. COVID-19 (novel coronavirus 2019)—recent trends. Eur Rev Med Pharmacol Sci 2020;24(4):2006–2011. DOI: 10.26355/eurrev_202002_20378.
Balazy A, Toivola M, Adhikari A, et al. Do N95 respirators provide 95% protection level against airborne viruses, and how adequate are surgical masks? Am J Infect Control 2006;34(2):51–57. DOI: 10.1016/j.ajic.2005.08.018.
Lawrence RB, Duling MG, Calvert CA, et al. Comparison of performance of three different types of respiratory protection devices. J Occup Environ Hyg 2006;3(9):465–474. DOI: 10.1080/15459620600829211.
Bischoff W, Turner J, Russell GB, et al. Evaluation of a novel powered airpurifying respirator (PAPR) vs. a N95 respirator mask for the protection against influenza in a human exposure model. Open Forum Infectious Diseases 2017;4(suppl-1):S168. DOI: 10.1093/ofid/ofx163.298.
Offeddu V, Yung CF, Low MSF, et al. Effectiveness of masks and respirators against respiratory infections in healthcare workers: a systematic review and meta-analysis. Clin Infect Dis 2017;65(11):1934–1942. DOI: 10.1093/cid/cix681.
Bartoszko JJ, Farooqi MAM, Alhazzani W, et al. Medical masks vs N95 respirators for preventing COVID-19 in health care workers a systematic review and meta-analysis of randomized trials. Influenza Other Respir Viruses 2020;14(4):365–373. DOI: 10.1111/irv.12745.
Bin-Reza F, Lopez Chavarrias V, Nicoll A, et al. The use of masks and respirators to prevent transmission of influenza: a systematic review of the scientific evidence. Influenza Other Respir Viruses 2012;6(4):257–267. DOI: 10.1111/j.1750-2659.2011.00307.x.
Radonovich LJ Jr, Simberkoff MS, Bessesen MT, et al. N95 respirators vs medical masks for preventing influenza among health care personnel: a randomized clinical trial. JAMA 2019;322(9):824–833. DOI: 10.1001/jama.2019.11645.
MacIntyre CR, Chughtai AA, Rahman B, et al. The efficacy of medical masks and respirators against respiratory infection in healthcare workers. Influenza Other Respir Viruses 2017;11(6):511–517. DOI: 10.1111/irv.12474.
Daugherty EL. Health care worker protection in mass casualty respiratory failure: infection control, decontamination, and personal protective equipment. Respir Care 2008;53(2):201–212; discussion 212–214.
Roberts V. To PAPR or not to PAPR? Can J Respir Ther 2014;50(3):87–90.
Jiang Q, Song S, Zhou J, et al. The prevalence, characteristics, and prevention status of skin injury caused by personal protective equipment among medical staff in fighting COVID-19: a multicenter, cross-sectional study. Adv Wound Care (New Rochelle) 2020;9(7):357–364. DOI: 10.1089/wound.2020.1212.
Li Y, Leung GM, Tang JW, et al. Role of ventilation in airborne transmission of infectious agents in the built environment—a multidisciplinary systematic review. Indoor Air 2007;17(1):2–18. DOI: 10.1111/j.1600-0668.2006.00445.x.
Ijaz MK, Zargar B, Wright KE, et al. Generic aspects of the airborne spread of human pathogens indoors and emerging air decontamination technologies. Am J Infect Control 2016;44(9 Suppl):S109–S120. DOI: 10.1016/j.ajic.2016.06.008.
Wei J, Li Y. Airborne spread of infectious agents in the indoor environment. Am J Infect Control 2016;44(9 Suppl):S102–S108. DOI: 10.1016/j.ajic.2016.06.003.
Ai ZT, Melikov AK. Airborne spread of expiratory droplet nuclei between the occupants of indoor environments: a review. Indoor Air 2018;28(4):500–524. DOI: 10.1111/ina.12465.
Zargar B, Sattar SA, Rubino JR, et al. A quantitative method to assess the role of indoor air decontamination to simultaneously reduce contamination of environmental surfaces: testing with vegetative and spore-forming bacteria. Lett Appl Microbiol 2019;68(3):206–211. DOI: 10.1111/lam.13109.
Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 2020;395(10223):497–506. DOI: 10.1016/S0140-6736(20)30183-5.
D'Ascanio L, Latini G, Pandolfini M, et al. Corona-steps for tracheotomy in COVID-19 patients: a staff-safe method for airway management. Oral Oncol 2020;106:104731. DOI: 10.1016/j.oraloncology.2020.104731.
Lu D, Wang H, Yu R, et al. Integrated infection control strategy to minimize nosocomial infection of corona virus disease 2019 among ENT healthcare workers. J Hosp Infect 2020;104(4):454–455. DOI: 10.1016/j.jhin.2020.02.018.
Pichi B, Mazzola F, Bonsembiante A, et al. CORONA-steps for tracheotomy in COVID-19 patients: a staff-safe method for airway management. Oral Oncol 2020;105:104682. DOI: 10.1016/j.oraloncology.2020.104682.
Vukkadala N, Qian ZJ, Holsinger FC, et al. COVID-19 and the otolaryngologist: preliminary evidence-based review. Laryngoscope 2020;130(11):2537–2543. DOI: 10.1002/lary.28672.
Wax RS, Christian MD. Practical recommendations for critical care and anesthesiology teams caring for novel coronavirus (2019-nCoV) patients. Can J Anaesth 2020;67(5):568–576. DOI: 10.1007/s12630-020-01591-x.
Guan WJ, Ni ZY, Hu Y, et al. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med 2020;382(18):1708–1720. DOI: 10.1056/NEJMoa2002032.
Bidra AS, Pelletier JS, Westover JB, et al. Rapid in-vitro inactivation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) using povidone-iodine oral antiseptic rinse. J Prosthodont 2020;29(6):529–533. DOI: 10.1111/jopr.13209.
Vergara-Buenaventura A, Castro-Ruiz C. Use of mouthwashes against COVID-19 in dentistry. Br J Oral Maxillofac Surg 2020;58(8):924–927. DOI: 10.1016/j.bjoms.2020.08.016.
Samaranayake LP, Reid J, Evans D. The efficacy of rubber dam isolation in reducing atmospheric bacterial contamination. ASDC J Dent Child 1989;56(6):442–444.
MaassenVanDenBrink A, de Vries T, Danser AHJ. Headache medication and the COVID-19 pandemic. J Headache Pain 2020;21(1):38. DOI: 10.1186/s10194-020-01106-5.
Sodhi M, Etminan M. Safety of ibuprofen in patients with COVID-19 causal or confounded? Chest 2020;158(1):55–56. DOI: 10.1016/j.chest.2020.03.040.
Day M. Covid-19: ibuprofen should not be used for managing symptoms, say doctors and scientists. BMJ 2020; 368:m1086. DOI: 10.1136/bmj.m1086.
Fang L, Karakiulakis G, Roth M. Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection? Lancet Respir Med 2020;8(4):e21. DOI: 10.1016/S2213-2600(20)30116-8.
Li YY, Wang JX, Chen X. Can a toilet promote virus transmission? From a fluid dynamics perspective. Phys Fluids (1994) 2020;32(6):065107. DOI: 10.1063/5.0013318.
Kowalski LP, Sanabria A, Ridge JA, et al. COVID-19 pandemic: effects and evidence-based recommendations for otolaryngology and head and neck surgery practice. Head Neck 2020;42(6):1259–1267. DOI: 10.1002/hed.26164.
Tseng C, Li C. Inactivation of surface viruses by gaseous ozone. J Environ Health 2008;70(10):56–62.
Holmes S, Bhatti N, Bhandari R, et al. Toward a consensus view in the management of acute facial injuries during the Covid-19 pandemic. Br J Oral Maxillofac Surg 2020;58(5):571–576. DOI: 10.1016/j.bjoms.2020.03.024.
Zimmermann M, Nkenke E. Approaches to the management of patients in oral and maxillofacial surgery during COVID-19 pandemic. J Craniomaxillofac Surg 2020;48(5):521–526. DOI: 10.1016/j.jcms.2020.03.011.
Trieu A, Mohamed A, Lynch E. Silver diamine fluoride versus sodium fluoride for arresting dentine caries in children: a systematic review and meta-analysis. Sci Rep 2019;9(1):2115. DOI: 10.1038/s41598-019-38569-9.
AL-Omiri MK, Kielbasa A, Lynch E. Ozone therapy. In: Graeber JJ, editor. Microinvasive Dentistry: Clinical Strategies and Tools. London: Jaypee Brothers Medical Publishers; 2020. pp. 153–159.
AL-Omiri MK, Alzoubi IA, Al Nazeh AA, et al. COVID-19 and personality: a cross-sectional multicenter study of the relationship between personality factors and COVID-19-related impacts, concerns, and behaviors. Front Psychiatry 2021;12:608730. DOI: 10.3389/fpsyt.2021.608730.
Ma ZF, Zhang Y, Luo X, et al. Increased stressful impact among general population in mainland China amid the COVID-19 pandemic: a nationwide cross-sectional study conducted after Wuhan city's travel ban was lifted. Int J Soc Psychiatry 2020;66(8):770–779. DOI: 10.1177/0020764020935489.
Buonanno M, Welch D, Shuryak I, et al. Far-UVC light (222 nm) efficiently and safely inactivates airborne human coronaviruses. Sci Rep 2020;10(1):10285. DOI: 10.1038/s41598-020-67211-2.
Yu L, Peel GK, Cheema FH, et al. Catching and killing of airborne SARS-CoV-2 to control spread of COVID-19 by a heated air disinfection system. Mater Today Phys 2020;15:100249. DOI: 10.1016/j.mtphys.2020.100249.