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VOLUME 23 , ISSUE 1 ( January, 2022 ) > List of Articles

ORIGINAL RESEARCH

Evaluation of Spheno-occipital Synchondrosis Fusion in Chinese Population Using CBCT: A Cross-sectional Study

Waseem S Al-Gumaei, Reem Al-Attab, Maged S Alhammadi, Remsh K Al-Rokhami, Abeer A Almashraqi, Ge Zhenlin, Ehab A Abdulghani, Yan Zheng

Keywords : Chinese population, Cone-beam computed tomography, Skeletal growth, Spheno-occipital synchondrosis, Stages of fusion

Citation Information : Al-Gumaei WS, Al-Attab R, Alhammadi MS, Al-Rokhami RK, Almashraqi AA, Zhenlin G, Abdulghani EA, Zheng Y. Evaluation of Spheno-occipital Synchondrosis Fusion in Chinese Population Using CBCT: A Cross-sectional Study. J Contemp Dent Pract 2022; 23 (1):8-13.

DOI: 10.5005/jp-journals-10024-3257

License: CC BY-NC 4.0

Published Online: 21-05-2022

Copyright Statement:  Copyright © 2022; The Author(s).


Abstract

Aim: This study sought to assess the fusion of spheno-occipital synchondrosis (SOS) in Chinese population using cone-beam computed tomography (CBCT). Materials and methods: This is a cross-sectional study in which data were randomly collected based on the pre-existing institutional records. Following selection criteria, the CBCT images of 500 patients aged 6–25 years (226 males and 274 females) were analyzed. Three-dimensional virtual models were oriented at a standardized position, then adjusted to the median sagittal plane (MSP) view. A four-stage scoring system was used; completely open, partially fused, semi-fused, or completely fused. The student's t-test, one-way ANOVA, Pearson correlation, and linear regression analysis were used and the significant level was set at ≤0.05. Results: The mean age of closure of stages 1, 2, 3, and 4 were 7.44, 9.62, 12.94, and 19.03 years in females, and 8.79, 11.13, 14.82, and 20.18 years in males, respectively. There was significantly strong positive correlation between spheno-occipital fusion and age (female: r = 0.853, male: r = 0.879; p <0.001), with 1.47 ± 0.33 years earlier fusion in females. All inter- and intra-stages mean ages were statistically significant in both genders. The transition age model demonstrated a mean age (in years) between stages 1–2 (10.1), stages 2–3 (12.79), and stage 3–4 (17.93) for males, and stages 1–2 (8.96), stages 2–3 (11.45), and stage 3–4 (16.69) for females. Conclusions: The present findings of SOS stages of fusion in both genders could guide age estimation and assessment of normal skeletal growth patterns and active skeletal growth period in the Chinese population. Clinical significance: There is still controversy about the time to closure of the SOS because of population and assessment technique variations. This study could be used as a reference for the specific examined population during planning for dentofacial orthopedic and/or orthognathic surgery and dental implant prosthesis for both genders. Moreover, these finding may be useful for medical purposes.


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  1. Björk A. Cranial base development: a follow-up x-ray study of the individual variation in growth occurring between the ages of 12 and 20 years and its relation to brain case and face development. Am J Orthod 1955;41(3):198–225. DOI: 10.1016/0002-9416(55)90005-1.
  2. Enlow DH, Hans MG. Essentials of facial growth. 3rd ed. Philadelphia, US: WB Saunders Company; 1996. p. 101–107.
  3. Madeline LA, Elster AD. Suture closure in the human chondrocranium: CT assessment. Radiology 1995;196(3):747–756. DOI: 10.1148/radiology.196.3.7644639.
  4. Jabour AS. Assessment of spheno-occipital synchondrosis fusion timing and an evaluation of its relationship with skeletal maturity, dental maturity and mandibular growth. Diss. US.: Case Western Reserve University; 2017.
  5. Demirturk Kocasarac H, Altan AB, Yerlikaya C, et al. Correlation between spheno-occipital synchondrosis, dental age, chronological age and cervical vertebrae maturation in Turkish population: is there a link? Acta Odontol Scand 2017;75(2):79–86. DOI: 10.1080/00016357.2016.1255352.
  6. Alhazmi A, Aldossary M, Palomo JM, et al. Correlation of spheno-occipital synchondrosis fusion stages with a hand-wrist skeletal maturity index: a cone beam computed tomography study. Angle Orthod 2021;(4):538–543. DOI: 10.2319/062920-596.1.
  7. Dillon ME. Comparison of spheno-occipital synchondrosis closure, cervical vertebrae maturation and hand-wrist maturation as skeletal maturation indicators. Diss. US.: University of Minnesota; 2018.
  8. Ok G, Sen Yilmaz B, Aksoy DO, et al. Maturity evaluation of orthodontically important anatomic structures with computed tomography. Eur J Orthod 2021;43(1):8–14. DOI: 10.1093/ejo/cjaa009.
  9. Bayrak S, Bulut DG. Relationship between condyle cortication, sphenooccipital synchondrosis, and chronological age. Oral Radiol 2020;36(2):190–196. DOI: 10.1007/s11282-019-00398-x.
  10. Alhazmi A, Vargas E, Palomo JM, et al. Timing and rate of spheno-occipital synchondrosis closure and its relationship to puberty. PLoS One 2017;12(8):e0183305. DOI: 10.1371/journal.pone.0183305.
  11. Baker MJ. Analysis of spheno-occipital synchondrosis (SOS) fusion in a contemporary southern nevada subadult hispanic population using archival cone-beam computerized tomography (CBCT) images. US.: University of Nevada; 2019.
  12. Shirley NR, Jantz RL. Spheno-occipital synchondrosis fusion in modern Americans. J Forensic Sci 2011;56(3):580–585. DOI: 10.1111/j.1556-4029.2011.01705.x.
  13. El-Barrany UMI, El din Ismail MM, Mohamed MA, et al. Estimation of age from spheno-occipital synchondrosis closure using computed tomography in Yemen. Egypt J Forensic Sci Appl Toxicol 2014;12: 75–89. DOI: 10.12816/0005083.
  14. Franklin D, Flavel A. Brief communication: timing of spheno-occipital closure in modern Western Australians. Am J Phys Anthropol 2014;153(1):132–138. DOI: 10.1002/ajpa.22399.
  15. Lottering N, MacGregor DM, Alston CL, et al. Ontogeny of the spheno-occipital synchondrosis in a modern Queensland, Australian population using computed tomography. Am J Phys Anthropol 2015;157(1):42–57. DOI: 10.1002/ajpa.22687.
  16. Ekizoglu O, Hocaoglu E, Can IO, et al. Spheno-occipital synchondrosis fusion degree as a method to estimate age: a preliminary, magnetic resonance imaging study. Aust J Forensic Sci 2016;48(2):159–170. DOI: 10.1080/00450618.2015.1042047.
  17. Sinanoglu A, Kocasarac HD, Noujeim M. Age estimation by an analysis of spheno-occipital synchondrosis using cone-beam computed tomography. Leg Med 2016;18:13–19. DOI: 10.1016/j.legalmed.2015.11.004.
  18. Hisham S, Flavel A, Abdullah N, et al. Quantification of spheno-occipital synchondrosis fusion in a contemporary Malaysian population. Forensic Sci Int 2018;284:78–84. DOI: 10.1016/j.forsciint.2017.12.046.
  19. Pate RS, Tingne CV, Dixit PG. Age determination by spheno-occipital synchondrosis fusion in Central Indian population. J Forensic Leg Med 2018;54:39–43. DOI: 10.1016/j.jflm.2017.12.013.
  20. Sharma A, Kumbhare SP, Kalaskar AR, et al. Age estimation in an Indian subpopulation by cone-beam computed tomographic analysis of spheno-occipital synchondrosis fusion. Forensic Sci Int 2020;2:100085. DOI: 10.1016/j.fsir.2020.100085.
  21. Okamoto T, Kubota K. Sol-gel transition of polysaccharide gellan gum. Carbohydrate Polym 1996;30(2–3):149–153. DOI: 10.1016/S0144-8617(96)00074-4.
  22. Can IO, Ekizoglu O, Hocaoglu E, et al. Forensic age estimation by spheno-occipital synchondrosis fusion degree: computed tomography analysis. J Craniofac Surg 2014;25(4):1212–1216. DOI: 10.1097/scs.0000000000000847.
  23. Bassed RB, Briggs C, Drummer OH. Analysis of time of closure of the spheno-occipital synchondrosis using computed tomography. Forensic Sci Int 2010;200(1–3):161–164. DOI: 10.1016/j.forsciint.2010.04.009.
  24. Kahana T, Birkby W, Goldin L, et al. Estimation of age in adolescents-the basilar synchondrosis. J Forensic Sci 2003;48(3):504–508. PMID: 12762517.
  25. Durtschi RB, Chung D, Gentry LR, et al. Developmental craniofacial anthropometry: assessment of race effects. Clin Anat 2009;22(7): 800–808. DOI: 10.1002/ca.20852.
  26. Buretić-Tomljanović A, Giacometti J, Ostojić S, et al. Sex-specific differences of craniofacial traits in Croatia: the impact of environment in a small geographic area. Ann Hum Biol 2007;34(3):296–314. DOI: 10.1080/03014460701211017.
  27. Fortanely BE. The influence of the spheno occipital synchondrosis fusion on craniofacial form [MSc Thesis.]. UK: University of British Columbia; 2020.
  28. Okamoto K, Ito J, Tokiguchi S, et al. High-resolution CT findings in the development of the sphenooccipital synchondrosis. AJNR Am J Neuroradiol 1996;17(1):117–120. PMID: 8770261.
  29. Landis JR, Koch GG. The measurement of observer agreement for categorical data. Biometrics 1977;33(1):159–174. PMID: 843571.
  30. Carmichael RP, Sándor GK. Dental implants, growth of the jaws, and determination of skeletal maturity. Atlas Oral Maxillofac Surg Clin North Am 2008;16(1):1–9. DOI: 10.1016/j.cxom.2007.10.003.
  31. Ngan P, Moon W. Evolution of Class III treatment in orthodontics. Am J Orthod Dentofacial Orthop 2015;148(1):22–36. DOI: 10.1016/j.ajodo.2015.04.012.
  32. Adem C, Lafitte F, Jarquin S, et al. The persistence of a spheno-occipital synchondrosis in an adult. J Radiol 1999;80(8):863–865. PMID: 10470617.
  33. Alio JJ, Lorenzo J, Iglesias C. Cranial base growth in patients with Down syndrome: a longitudinal study. Am J Orthod Dentofacial Orthop 2008;133(5):729–737. DOI: 10.1016/j.ajodo.2006.03.036.
  34. Goldstein JA, Paliga JT, Wink JD, et al. Earlier evidence of spheno-occipital synchondrosis fusion correlates with severity of midface hypoplasia in patients with syndromic craniosynostosis. Plast Reconstr Surg 2014;134(3):504–510. DOI: 10.1097/PRS.0000000000000419.
  35. Graf CC, Dritsas K, Ghamri M, et al. Reliability of cephalometric superimposition for the assessment of craniofacial changes: a systematic review. Eur J Orthod 2022:cjab082. DOI: 10.1093/ejo/cjab082.
  36. Sobh ZK, Mohamed AS. A computed tomographic analysis of spheno-occipital synchondrosis ossification for age estimation in a sample of Egyptians. Am J Forensic Med Pathol 2021;42(3):235–242. DOI: 10.1097/PAF.0000000000000645.
  37. Kocasarac HD, Sinanoglu A, Noujeim M, et al. Radiologic assessment of third molar tooth and spheno-occipital synchondrosis for age estimation: a multiple regression analysis study. Int J Legal Med 2016;130(3):799–808. DOI: 10.1007/s00414-015-1298-8.
  38. Lei Y, Luo D, Yan X, et al. The mean age of menarche among Chinese schoolgirls declined by 6 months from 2005 to 2014. Acta Paediatr 2021;110(2):549–555. DOI: 10.1111/apa.15441.
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