Citation Information :
Ajay R, Rakshagan V, Queenalice A, Vinothkumar S, Ravivarman C, Saravanadinesh P. Effect of Triazine Comonomer Substitution on the Structure and Glass Transition Temperature of Monomethacrylate-based Resin Polymer: An In Vitro Study. J Contemp Dent Pract 2022; 23 (2):202-207.
Aim and objectives: The present research aimed to characterize and deduce the structure of a novel denture base copolymer containing antimicrobial triazine comonomer by nuclear magnetic resonance (NMR) and energy-dispersive X-ray (EDX) spectroscopies. Also, it aimed to evaluate the glass transition temperature (Tg) with the addition of TATA at different concentrations.
Materials and methods: The trial groups G10 and G20 were thermo-polymerized with triazine comonomer, whereas the control group G0 was polymerized without the triazine. NMR and EDX spectroscopies assessed copolymerization along with deducing elemental composition in mass %. The surface topographies were observed through field-emission scanning electron microscopy (FESEM). The Tg of the resultant copolymer was examined by differential scanning calorimetry. Pertinent statistical tests with relevant multiple comparison tests were exercised to compare the mean Tg of the groups.
Results: The configuration of a new copolymer containing triazine comonomer was manifested with additional protons and carbon atoms. Nitrogen was detected in the EDX spectroscopy of the trial groups. The Tg of the new copolymer was higher than the G0. The triazine comonomer in the copolymer at 20% concentration exhibited the highest Tg.
Conclusion: The triazine comonomer substitution produced a novel denture base copolymer with enhanced Tg.
Clinical significance: The novel denture base copolymer may possess enhanced biomechanical properties due to the TATA's cross-linking capability. Nevertheless, the antimicrobial property of the triazine comonomer incorporated in the denture base composition might be beneficial in inhibiting the microbial colonization on the denture's surface.
Brożek R, Koczorowski R, Rogalewicz R, et al. Effect of denture cleansers on chemical and mechanical behavior of selected soft lining materials. Dent Mater 2011;27(3):281–290. DOI: 10.1016/j.dental.2010.11.003.
Saitoh S, Sasaki K, Nezu T, et al. Viscoelastic behavior of commercially available tissue conditioners under compression. Dent Mater J 2010;29(4):461–468. DOI: 10.4012/dmj.2009-130.
Ferracane JL, Greener EH. The effect of resin formulation on the degree of conversion and mechanical properties of dental restorative resins. J Biomed Mater Res 1986;20(1):121–131. DOI: 10.1002/jbm.820200111.
Sostena MM, Nogueira RA, Grandini CR, et al. Glass transition and degree of conversion of a light-cured orthodontic composite. J Appl Oral Sci 2009;17(6):570–573. DOI: 10.1590/s1678-77572009000600006.
Braden M, Stafford GD. Viscoelastic properties of some denture base materials. J Dent Res 1968;47(4):519–523. DOI: 10.1177/00220345680470040201.
Fox Tg, Loshaek S. Influence of molecular weight and degree of crosslinking on the specific volume and glass temperature of polymers. J Polym Sci 1955;15:371–390. DOI: 10.1002/pol.1955.120158006.
Barsby MJ, Braden M. Visco-elastic properties of pour (fluid) denture base resins. J Dent Res 1981;60(2):146–148. DOI: 10.1177/00220345810600020901.
Ajay R, Suma K, Ali SA. Monomer modifications of denture base acrylic resin: a systematic review and meta-analysis. J Pharm Bioallied Sci 2019;11(Suppl 2):S112–S125. DOI: 10.4103/JPBS.JPBS_34_19.
Ajay R, Suma K, JayaKrishnakumar S, et al. Chemical characterization of denture base resin with a novel cycloaliphatic monomer. J Contemp Dent Pract 2019;20(8):940–946. DOI: 10.5005/jp-journals-10024-2634.
Ajay R, Suma K, Sasikala R, et al. Chemical structure and physical properties of heat-cured poly(methyl methacrylate) resin processed with cycloaliphatic comonomer: an in vitro study. J Contemp Dent Pract 2020;21(3):285–290. DOI: 10.5005/jp-journals-10024-2769.
Li P, Xu R, Wang W, et al. Thermosensitive poly(N-isopropyl acrylamide-co-glycidyl methacrylate) microgels for controlled drug release. Colloids Surf B Biointerfaces 2013;101(1):251–255. DOI: 10.1016/j. colsurfb.2012.07.009.
Bhat HR, Singh UP, Thakur A, et al. Synthesis, antimalarial activity and molecular docking of hybrid 4-aminoquinoline-1,3, 5-triazine derivatives. Exp Parasitol 2015;157:59–67. DOI: 10.1016/j.exppara.2015.06.016.
Singh B, Bhat HR, Kumawat MK, et al. Structure-guided discovery of 1,3,5-triazine-pyrazole conjugates as antibacterial and antibiofilm agent against pathogens causing human diseases with favorable metabolic fate. Bioorg Med Chem Lett 2014;24(15):3321–3325. DOI: 10.1016/j.bmcl.2014.05.103.
Zhou C, Min J, Liu Z, et al. Synthesis and biological evaluation of novel 1,3,5-triazine derivatives as antimicrobial agents. Bioorg Med Chem Lett 2008;18(4):1308–1311. DOI: 10.1016/j.bmcl.2008.01.031.
Altmann AS, Collares FM, Ogliari FA, et al. Effect of methacrylated-based antibacterial monomer on orthodontic adhesive system properties. Am J Orthod Dentofacial Orthop 2015;147:S82–S87. DOI: 10.1016/j.ajodo.2015.01.015.
Ranganathan A, Karthigeyan S, Chellapillai R, et al. Effect of novel cycloaliphatic comonomer on the flexural and impact strength of heat-cure denture base resin. J Oral Sci 2020;63(1):14–17. DOI: 10.2334/josnusd.19-0493.
Ajay R, Suma K, Rakshagan V, et al. Effect of novel cycloaliphatic comonomer on surface roughness and surface hardness of heat-cure denture base resin. J Pharm Bioallied Sci 2020;12(Suppl. 1):S67–S72. DOI: 10.4103/jpbs.JPBS_20_20.
He J, Söderling E, Österblad M, et al. Synthesis of methacrylate monomers with antibacterial effects against S. mutans. Molecules 2011;16(11):9755–9763. DOI: 10.3390/molecules16119755.
Aydogan Ayaz E, Durkan R. Influence of acrylamide monomer addition to the acrylic denture-base resins on mechanical and physical properties. Int J Oral Sci 2013;5(4):229–235. DOI: 10.1038/ijos.2013.69.
Stutz H, Illers KH, Mertes J. A generalized theory for the glass transition temperature of crosslinked and uncrosslinked polymers. J Polym Sci B Polym Phys 1990;28:1483–1498. DOI: 10.1002/polb.1990.090280906.
Jerolimov V, Jagger RG, Millward PJ. Effect of cross-linking chain length on glass transition of a dough-moulded poly (methylmethacrylate) resins. Acta Stomatol Croat 1994;28(1):3–9. Available from: https://hrcak.srce.hr/99263.
Jerolimov V, Jagger RG, Milward PJ. Effect of the curing cycle on acrylic denture base glass transition temperatures. J Dent 1991;19(4):245–248. DOI: 10.1016/0300-5712(91)90128-l.
Hayashi R, Kubota T, Mega J. Application of fluoroalkyl acrylate monomer for a denture base material. Int J Oral-Med Sci 2003;1(2): 124–129. DOI: 10.5466/ijoms.1.124.
Kubota T, Kobayashi M, Hayashi R, et al. Influence of carbon chain length of fluorinated alkyl acrylate on mechanical properties of denture base resin. Int J Oral-Med Sci 2005;4(2):92–96. DOI: 10.5466/ijoms.4.92.
Spasojevic P, Zrilic M, Panic V, et al. The mechanical properties of a poly(methyl methacrylate) denture base material modified with dimethyl itaconate and di-n-butyl Itaconate. Int J Polym Sci 2015;561012. DOI: 10.1155/2015/561012.
Spasojevic P, Panic V, Seslija S, et al. Poly(methyl methacrylate) denture base materials modified with ditetrahydro furfuryl itaconate: significant applicative properties. J Serb Chem Soc 2015;80(9): 1177–1192. DOI: 10.2298/JSC150123034S.
Rodriguez LS, Paleari AG, Giro G, et al. Chemical characterization and flexural strength of a denture base acrylic resin with monomer 2-tert-butylaminoethyl methacrylate. J Prosthodont 2013;22(4): 292–297. DOI: 10.1111/j.1532-849X.2012.00942.x.
Ruyter IE, Svendsen SA. Flexural properties of denture base polymers. J Prosthet Dent 1980;43(1):95–104. DOI: 10.1016/0022-3913(80) 90362-5.
Fox Tg, Flory PJ. The glass temperature and related properties of polystyrene. Influence of molecular weight. J Polym Sci 1954;14: 315–319. DOI: 10.1002/pol.1954.120147514.