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VOLUME 25 , ISSUE 3 ( March, 2024 ) > List of Articles

ORIGINAL RESEARCH

Evaluation of Fibrin Clot Interaction with Dental Implant after Different Surface Treatments: An In Vitro Study

Mohammad Jalaluddin, Pavithra K Ramanna, Monalisa Swain, Subhash Sonkesriya, Priyanka Rana, Deesha Kumari, Dina A A Derbala, Linda F Mirza, Shazia Mushtaq, Saiid E M Beshir

Keywords : Dental implant, Fibrin clot, Surface treatment, Venous blood

Citation Information : Jalaluddin M, Ramanna PK, Swain M, Sonkesriya S, Rana P, Kumari D, Derbala DA, Mirza LF, Mushtaq S, Beshir SE. Evaluation of Fibrin Clot Interaction with Dental Implant after Different Surface Treatments: An In Vitro Study. J Contemp Dent Pract 2024; 25 (3):276-279.

DOI: 10.5005/jp-journals-10024-3653

License: CC BY-NC 4.0

Published Online: 19-04-2024

Copyright Statement:  Copyright © 2024; The Author(s).


Abstract

Aim: The current study was carried out to assess the interaction between fibrin clots and dental implants following various surface treatments. Materials and methods: In this investigation, 45 dental implants with dimensions of 16 mm in length and 5 mm in diameter were utilized. They were divided up into three groups, each consisting of fifteen samples. Group I: Control; Group II: Ultraviolet (UV) light treated; and group III: Sandblasted and acid-etching (SLA) treated. Healthy volunteers’ venous blood samples were drawn into vacutainer tubes without the use of anticoagulants. The samples were centrifuged for 3 minutes at 2700 rpm in a table centrifuge. The entire implant was submerged in room-temperature liquid fibrinogen for 60 minutes. Then, scanning electronic microscopy (SEM) was used to examine each sample. The inter- and intragroup assessments were obtained using the Mann–Whitney U test and the Kruskal–Wallis test; p-values less than 0.05 were regarded as statistically significant. Results: The maximum adhesion of fibrin clot was found in SLA treated group (2.42 ± 0.10) followed by the UV light-treated group (2.18 ± 0.08) and control group (1.20 ± 0.02). There was a statistically significant difference found between the three surface-treated groups (p < 0.001). Conclusion: All surface-treatment methods exhibit adhesion between the implant surface and the fibrin clot. However, the highest adherence of fibrin clot was found in SLA treated group compared to the UV light-treated and control group. Clinical significance: The physical and chemical characteristics of an implant's surface have a significant impact on the way blood clots organize. At the interface between the implant and the bone, blood clot production can initiate and facilitate the healing process.


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