The Journal of Contemporary Dental Practice

Register      Login



Volume / Issue

Online First

Related articles

VOLUME 4 , ISSUE 2 ( May, 2003 ) > List of Articles


Effects of a Betaine-containing Toothpaste on Subjective Symptoms of Dry Mouth: A Randomized Clinical Trial

Irma Rantanen, Jorma Tenovuo, Kaisu Pienihäkkinen, Eva Söderling

Citation Information : Rantanen I, Tenovuo J, Pienihäkkinen K, Söderling E. Effects of a Betaine-containing Toothpaste on Subjective Symptoms of Dry Mouth: A Randomized Clinical Trial. J Contemp Dent Pract 2003; 4 (2):11-23.

DOI: 10.5005/jcdp-4-2-11

License: CC BY-NC 3.0

Published Online: 01-08-2005

Copyright Statement:  Copyright © 2003; The Author(s).



Rantanen I, Tenovuo J, Pienihäkkinen K, et. al. Effects of a betaine-containing toothpaste on subjective symptoms of dry mouth, a randomised clinical trial. J Contemp Dent Pract 2003 May;(4)2:011-023.

PDF Share
  1. Individual diagnosis, prognosis and counselling for caries prevention. Caries Res. 1978;12 Suppl 1:94-102. No abstract available.
  2. Xerostomia and hyposalivation. Adv Dent Res. 2000 Dec;14:48-56. Review.
  3. al. Prevalence of perceived symptoms of dry mouth in an adult Swedish population-relation to age, sex and pharmacotherapy. Community Dent Oral Epidemiol. 1997 Jun;25(3):211-6.
  4. al. Prevalence of symptoms of dry mouth and their relationship to saliva production in community dwelling elderly: the SEE project. Salisbury Eye Evaluation. J Rheumatol. 1998 Mar;25(3):486-91.
  5. Dry mouth and salivary gland hypofunction, Part II: Etiology and patient evaluation. Compendium. 1988 Sep;9(8):630-1, 634-5, 638 passim. No abstract available.
  6. Sjögren's syndrome: oral and dental considerations. J Am Dent Assoc. 1993 Mar;124(3):74-6, 78-82, 84-6. Review.
  7. al. Sjögrenin oireyhtymä. Suomen Lääkärilehti 1999;26:3061-3073.
  8. Dry mouth and salivary gland hypofunction, Part I: Diagnosis. Compendium. 1988 Jul-Aug;9(7):569-70, 573-4, 576 passim. No abstract available.
  9. Oral manifestations associated with Sjögren's syndrome: clinic, diagnosis and treatment. Tandläkartidningen 1988;80:896-902.
  10. Dry mouth and salivary gland hypofunction, Part III: Treatment. Compendium. 1988 Oct;9(9):716-7, 720-1. No abstract available.
  11. Electrical stimulation of salivary flow in patients with Sjögren's syndrome. J Dent Res. 1988 Oct;67(10):1334-7.
  12. Clinical implications of the dry mouth. Oral mucosal diseases. Ann N Y Acad Sci. 1998 Apr 15;842:156-62. Review.
  13. Relationship between salivary flow rates and Candida albicans counts. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1995 Sep;80(3):284-8.
  14. Caries prevalence in xerostomic individuals. J Can Dent Assoc. 1993 Feb;59(2):171-4, 177-9.
  15. al. Prevalence of periodontal disease in patients with Sjögren's syndrome. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1997 Apr;83(4):453-7.
  16. Dentifrices. In: Newbrun E. Cariology. 3rd ed. Chicago, IL: Quintessence, 1989;274-290.
  17. al. Effects of oral rinsing with triclosan and sodium lauryl sulphate on dental plaque formation: a pilot study. Scand J Dent Res. 1993 Aug;101(4):192-5.
  18. Oral mucosal desquamation of pre- and post-menopausal women. A comparison of response to sodium lauryl sulphate in toothpastes. J Clin Periodontol. 1996 Jun;23(6):567-71.
  19. Oral mucosal desquamation caused by two toothpaste detergents in an experimental model. Eur J Oral Sci. 1996 Feb;104(1):21-6.
  20. The sodium lauryl sulphate model: an overview. Contact Dermatitis. 1995 Jul;33(1):1-7. Review.
  21. Skin reactions to irritants assessed by non-invasive bioengineering methods. Contact Dermatitis 1989;20:352-359.
  22. al. Different skin irritation abilities of different qualities of sodium lauryl sulphate. Contact Dermatitis. 1989 Sep;21(3):184-8.
  23. Sodium-lauryl-sulphate-induced cutaneous irritation. Comparison of white and Hispanic subjects. Contact Dermatitis. 1988 Aug;19(2):136-40.
  24. The effect of two toothpaste detergents on the frequency of recurrent aphthous ulcers. Acta Odontol Scand. 1996 Jun;54(3):150-3.
  25. al. Genetic engineering of glycinebetaine production toward enhancing stress tolerance in plants: metabolic limitations. Plant Physiol 2000;122:747-756.
  26. A method of reducing the irritating properties of a cosmetic composition. International patent 1991. WO 91/18588.
  27. EPO patent 0531387, 1996.
  28. al. The ability of betaine to reduce the irritating effects of detergents assessed visually, histologically and by bioengineering methods. Skin Res Technol. 2003 Feb;9(1):50-8.
  29. al. Betaine-containing toothpaste relieves subjective symptoms of dry mouth. Acta Odontol Scand. 1998 Apr;56(2):65-9.
  30. A comparison between the plaque indices of Silness-Löe and Greene-Vermillion. J Pedod. 1980 Fall;5(1):51-61. No abstract available.
  31. Reduced plaque formation by the chloromethyl analogue of vitamin C. J Periodontol 1970;41:41-43.
  32. al. Retention of topical fluoride in the mouths of xerostomic subjects. Caries Res. 1988;22(5):306-10.
  33. Contact allergens in toothpastes and a review of their hypersensitivity. Contact Dermatitis. 1995 Aug;33(2):100-5. Review.
  34. Factors contributing to adverse soft tissue reactions due to the use of tartar control toothpastes: report of a case and literature review. J Periodontol. 1999 Jul;70(7):803-7. Review.
  35. Sodium lauryl sulfate and recurrent aphthous ulcers. A preliminary study. Acta Odontol Scand. 1994 Oct;52(5):257-9.
  36. al. The effect of a sodium lauryl sulfate-free dentifrice on patient with recurrent oral ulceration. Oral Dis. 1999 Jan;5(1):39-43.
  37. Considerations concerning the sodium lauryl sulphate content of dentifrices. In:Embery G, Rölla G, eds. Clinical and biological aspects of dentifrices. London: Oxford University Press, 1992;173-180.
  38. The effects of two sodium lauryl sulphate-containing toothpastes with and without betain on human oral mucosa in vivo. Swed Dent J. 2003, 27(1):31-34.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.