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VOLUME 8 , ISSUE 5 ( July, 2007 ) > List of Articles

RESEARCH ARTICLE

A Pigmented Dentigerous Cyst in a Patient with Multiple Dentigerous Cysts of the Jaws: A Case Report

Shokoufeh Shahrabi Farahani, Mohammadtaghi Lotfalian

Citation Information : Farahani SS, Lotfalian M. A Pigmented Dentigerous Cyst in a Patient with Multiple Dentigerous Cysts of the Jaws: A Case Report. J Contemp Dent Pract 2007; 8 (5):85-91.

DOI: 10.5005/jcdp-8-5-85

License: CC BY-NC 3.0

Published Online: 01-07-2007

Copyright Statement:  Copyright © 2007; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Aim

The aim of this article is to report an unusual and interesting case of non-syndromic multiple dentigerous cysts of the maxilla and mandible associated with melanin pigment and melanocytes in the epithelial lining in one of the cysts. In addition, embryologic aspect and origin of melanocytes are briefly discussed.

Background

Dentigerous cysts are the second most common odontogenic cysts after radicular cysts. They are usually solitary with multiple cysts reported on occasion in association with syndromes. While melanocytes and melanin-pigment are widely distributed in the skin, the nervous system, certain types of mucosa, uveal tract, and other areas, they are not normally present within bone in mammals.

Report

A 37-year-old Iranian male was referred to an oral surgeon by his dentist for evaluation and treatment of multiple cyst-like radiolucent lesions around the crowns of some unerupted permanent teeth in both maxillary and mandibular anterior areas. The biopsy revealed numerous granules of melanin-pigment distributed throughout the epithelial lining of one of these cysts in addition to the characteristic histopathologic features of adentigerous cyst. Histochemical analysis confirmed the pigment was melanin, and many of the cells containing melanin were immunohistochemically positive for s-100 protein.

Summary

Although the specific origin and pathologic significance of the melanocytes described here cannot be explained, it may be of interest for future investigations.

Citation

Shahrabi Farahani S, Lotfalian M. A Pigmented Dentigerous Cyst in a Patient with Multiple Dentigerous Cysts of the Jaws: A Case Report. J Contemp Dent Pract 2007 July;(8)5:085-091.


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  1. Spontaneous regression of bilateral dentigerous cysts associated with impacted mandibular third molars. Br Dent J 2002;192(2):75-76.
  2. Bilateral maxillary dentigerous cysts: A case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2003;95(5):632-5.
  3. Case report of a pigmented dentigerous cyst and a review of the literature on pigmented odontogenic cysts. J Oral Sci 2000;42(1):43-46.
  4. Melanin pigment in ghost cells of a complex odontoma. J Nihon Univ Sch Dent 1998;31:502-506.
  5. Melanocytes in malignant ameloblastoma, case report. Pathology international 1996;46:777-781.
  6. A pigmented adenomatoid odontogenic tumor. Oral Surg Oral Med Oral Pathol 1990;70(1):86-9.
  7. A pigmented odontogenic keratocyst. Br J Oral Maxillofac Surg 1985;23:216-219.
  8. Pigmented ameloblastic fibrodentinoma: a novel melanin-pigment intraosseous odontogenic lesion. Virchows Arch 2000;437(4):454-8.
  9. Multiple dentigerous cysts in several facial bones. Oral Surg Oral Med Oral Pathol 1979;48(5):492.
  10. Occurrence of multiple dentigerous cysts in a patient with the Maroteaux-Lamy syndrome (mucopolysaccharidosis, type V). Oral Surg Oral Med Oral Pathol 1984;58(2):169-75.
  11. Bilateral mandibular cysts associated with cyclosporine use: a case report. Pediatr Nephrol 2001;16:993-5.
  12. Multiple dentigerous cysts associated with arachnodactyly and other skeletal defects. Report of a case. Oral Surg Oral Med Oral Pathol 1968;25(1):99-107.
  13. Multiple dentigerous cysts in childhood. J Otolaryngol 1996; 25(4): 267-70.
  14. Pigmented variant of calcifying odontogenic cyst. Report of an additional case and review of the literature. Acta Pathol. Jpn 1985;35:1023-1027.
  15. Pigmented periodontal cyst and other pigmented odontogenic lesions. Oral Dis 1996;2(4):299-302.
  16. A pigmented calcifying odontogenic cyst. Oral Surg Oral Med Oral Pathol 1982;53:395.
  17. Pigmented gingival cyst. Oral Surg Oral Med Oral Pathol 1964;17:635-639.
  18. The odontogenic keratocyst. Histologic features and their correlation with clinical behavior. Br Dent J 1977;131:249-259.
  19. The odontogenic keratocyst. A clinicopathologic study of 312 cases. Part 2. Oral Surg Oral Med Oral Pathol 1977;43:233-255.
  20. Melanocytes in odontogenic keratocyst. Acta Pathol. Jpn 1985;35:899-903.
  21. The lateral periodontal cyst: an update. J Oral Pathol Med 1992;21:245-250.
  22. Melanin-pigment in complex odontoma. Int J Oral Maxillofac Surg 1987;16(2):222-6.
  23. Melanin in a dentigerous cyst and associated adenomatoid odontogenic tumor. Cancer 1990;66:786-788.
  24. Studies on melanocytes. V. The presence of melanocytes in the human dental primordium: An explanation for pigmented lesions of the jaws. Oral Surg 1976; 42(3): 375-380.
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