Tobacco Use and Its Effects on the Periodontium and Periodontal Therapy
Vandana K. Laxman, Sridhar Annaji
Citation Information :
Laxman VK, Annaji S. Tobacco Use and Its Effects on the Periodontium and Periodontal Therapy. J Contemp Dent Pract 2008; 9 (7):97-107.
CC BY-NC 3.0
Copyright © 2008; Jaypee Brothers Medical Publishers (P) Ltd.
The purpose of this article is to present a review of the potential biological mechanisms underlying the effects of tobacco smoking on periodontal health and periodontal therapy.
Periodontitis is the result of complex interrelationships between infectious agents and host factors. Environmental, acquired, and genetic risk factors modify the expression of disease and may, therefore, affect the onset or progression of periodontitis.
The study of the relationship between periodontal disease and smoking has received increased attention during the last few years. Tobacco smoking has wide spread systemic effects, many of which may provide mechanisms for the increased susceptibility to periodontitis and the poorer response to treatment.
Tobacco smoking is a significant risk factor for periodontal disease.
The role smoking plays in periodontal disease should be considered by clinicians and patients during active periodontal therapy and the oral health maintenance phases of care.
Laxman VK, Annaji S. Tobacco Use and Its Effects on the Periodontium and Periodontal Therapy. J Contemp Dent Pract 2008 November; (9)7:097-107.
Cigarette smoking and the periodontal patient. State of the Art Review. J Periodontol 2004; 75:196-209.
Evidence for cigarette smoking as a major risk factor for periodontitis. J Periodontal 1993; 64:16-23.
Cigarette smoking and periodontitis: methodology to assess the strength of evidence in support of a causal association. Community Dent Oral Epidemol 1999; 27:16-24.
Cigarette smoking and periodontal disease: Etiology and management of disease. Ann Periodontology 1998; 3:88-101.
9th edi. 2003 Saunders publications. 14th chapt. p-245.
Tobacco use among students in the eight north-eastern states of India. Indian J Cancer 2003; 2:43-59.
Tobacco control in India. Indian J Dent Res 2007; 18(1):2-5.
Aetiology of Acute necrotizing Ulcerative Gingivitis: A hypothetical explanation. J Periodontol 1974; 45:830-2.
Assessment of risk for periodontal disease. I Risk indicator for attachment loss. J Periodontol 1994; 65:260-7.
The role of smoking in periodontal diseases: A review of the literature. Periodontal abstracts 1993; 41(1):5-9.
Cigarette smoking and periodontal diseases: Etiology and management of disease. Ann Periodontol 1998; 3:88-101.
Mechanism of action of environmental factors – Tobacco smoking. J Clin Periodontol 2005; 32(suppl. 6):180-95.
Effects of periodontitis and smoking on the microbiota of oral mucous membranes and saliva in systemically healthy subjects. J Clin Periodontol 2003; 30:1031-7.
Oral microbiota in smokers and non-smokers in natural and experimentally induced gingivitis. J Clin Periodontol 1998; 25:677-86.
Cigarette smoking increases the risk for subgingival infection with periodontal pathogens. J Periodontol 1996; 67(suppl.):1050-4.
Clinical and microbiological characteristics of smokers with early onset periodontitis. J Periodont Res 199; 34:25-33.
The influence of cigarette smoking on the development of experimental gingivitis. J Periodont Res 1986; 21:668-76.
The effects of intra-arterial epinephrine and nicotine on gingival circulation. Oral Surg Oral Med Oral Path 1981; 52:577-82.
Central nicotinic stimulation reduces vascular conductance in the gingiva in anesthetized rats. J Periodont Res 2005; 40:67-72.
The effect of cigarette smoking on gingival blood flow in humans. J Clin Periodontol 1987; 14:418-24.
Laser dopler flow meter measurement of relative gingival and forehead skin blood flow in light and regular smoking during and after smoking. J Clin Periodontol 2000; 23:236-42.
Immunohistochemical study of vestibular gingival blood vessel density and internal circumeference in smokers and non-smokers. J Periodontol 2001; 72:1318-23.
Tobacco smoking and gingival nuetrophil activity in young adults. J Clin Periodontol 1999; 26:9-13.
Clinical expression of TNF-α in smoking associated periodontal disease. J Clin Periodontol 1998; 25:767-73.
IL-1 and receptor antagonists level in GCF in heavy smokers versus non-smokers. J Clin Periodontol 2003; 30:42-8.
Effects of tobacco products on the attachment and growth of periodontal ligament fibroblasts. J Periodontol 1991; 70:518-25.
Effects of nicotine on periodontal ligament fibroblasts in vitro. J Clin Periodontol 199; 26:49-55.
Prognosis versus actual outcome IV. The effectiveness of clinical parameters and IL-1 genotype in accurately predicting prognosis and survival. J Periodontol 1999; 70:49-56.
A longitudinal study of interleukin-1 gene polymorphisms and periodontal disease in a general population. J Clin Periodontol 2001; 28:1137-44.
Tobacco and smoking: Environmental factors that modify the host response (immune system) and have an impact on periodontal health. Crit Rev Oral Biol Med 1997; 8:437-60.
The effect of cigarette smoke on human oral polymorphonuclear leukocytes. J Periodont Res 1977; 12:227.
Comparison of leukocyte count and function in smoking and non-smoking young men. Infect Immun 1975; 12:550.
Smoking and periodontal disease. J Periodontol 1986; 57:617-24.
Tobacco use as a risk factor. J Periodontol 1994; 65(suppl):545-50.
Cigarette smoking and periodontal destruction in young adults. J Periodontol 1994; 65:718-23.
Effect of cigarette smoking on periodontal status of healthy young adults. J Periodontol 2000; 71:73-8.
Smoking and its effects on early onset periodontitis. J Am Dent Assoc 1995; 126:1107-13.
Relationship of cigarette smoking to attachment level profiles. J Clin Periodontol 2001; 28:283-95.
Periodontal diseases: Epidemiology. Ann Periodontol 1996; 1:1-36.
Effects of smoking on periodontal tissues. J Clin Periodontol 2002; 29:771-6.
Tobacco smoking and supra-gingival dental calculus. J Clin Periodontol 1999; 26:541-7.
Smoking-attributable periodontitis in the United States: findings from NHANES III. J Periodontol 2000; 71:743-51.
Epidemiologic risk factors for periodontal attachment loss among adults in the United States. J Clin Periodontol 2003; 30:230-7.
Assessment of risk for periodontal disease. I Risk indicator for alveolar bone loss. J Periodontol 1995; 66:23-9.
Smoking and periodontal disease severity. J Clin Periodontol 1995; 22:743-9.
Association between smoking and gingival bleeding in rural Sri Lanka. Jol Clin Periodontol 2003; 30:403-8.
Tobacco use and oral hygiene as risk indicators for periodontitis. Community Dent Oral Epidemiol 2002; 30:115-23.
Effects of areca nut extracts on the functions of human neutrophils in vitro. J Periodontal Res 2000; 35:186-93.
Association between betal quid chewing, periodontal status and periodontal pathogens. Oral Microbiology and Immunology 2001; 16:364-9.
Areca nut extracts inhibits the growth, attachment, and matrix protein synthesis of cultured human gingival fibroblasts. J Periodontol 1998; 69:1092-7.
Effects of smoking and smoking cessation on healing after mechanical periodontal therapy. J Am Dent Assoc 1997; 28:599-607.
Comparison of treatment response patterns following scaling and root planing in smokers and non-smokers with untreated adult periodontitis. J Clin Dent 2000; 11:35-41.
Cigarette smoking negatively affects healing response following flap debridement surgery. J Periodontol 2001; 72:43-9.
Longitudinal effect of non-surgical treatment and systemic metronidazole for 1 week in smokers and non-smokers with refractory periodontitis: A 5 year study. J Periodontol 1999; 70:761-71.
The effect of smoking on periodontal treatment response: A review of clinical evidence. J Clin Periodontol 2006;33:241-53.
Adjunctive benefits of sub-antimicrobial dose doxycycline in the management of severe, generalized, chronic periodontitis. J Periodontol 2002; 73:766-9.
The connective tissue with partial thickness double pedicle graft: The results of 100 consecutively treated defects. J Periodontol 1994; 65:448-61.
Coronally positioned flap procedures with or without a bioresorbable membrane in the treatment of human gingival recession. J Periodontol 2000; 71:989-98.
Healing response of gingival recession defects following guided tissue regeneration procedures in smokers and non-smokers. J Clin Periodontol 1997; 24:529-33.
Long term stbility of clinical attachment following guided tissue regeneration and conventional therapy. J Clin Periodontol 1996; 23:106-11.
Cigarette smoking in a periodontal practice. J Periodontol 1992; 63:100-6.
Cigarette smoking and periodontal bone loss. J Periodontol 1991; 62:242-6.
The effect of changed smoking habits on marginal alveolar bone loss. A longitudinal study. Swed Dent J 1993; 17:211-6.
Cigar, pipe and cigarette smoking as a risk factor for periodontal disease and tooth loss. J Periodontol 2000; 71:1874-81.
A 10-year prospective study of tobacco smoking and periodontal health. J Periodontol 2000;71:1338-47.