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VOLUME 12 , ISSUE 2 ( March-April, 2011 ) > List of Articles

RESEARCH ARTICLE

Retrospective Study of 25 Cases of Keratocystic Odontogenic Tumor: Epidemiology and Treatment

Juliana L Schussel, Roberta T Stramandinoli, Jose Luis Dissenha, Lucia FC Avila, Laurindo M Sassi

Citation Information : Schussel JL, Stramandinoli RT, Dissenha JL, Avila LF, Sassi LM. Retrospective Study of 25 Cases of Keratocystic Odontogenic Tumor: Epidemiology and Treatment. J Contemp Dent Pract 2011; 12 (2):100-103.

DOI: 10.5005/jp-journals-10024-1016

Published Online: 00-04-2011

Copyright Statement:  Copyright © 2011; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Aim

Keratocystic odontogenic tumor (KOT) is a benign odontogenic neoplasm with locally aggressive behavior and high recurrence rates. It is associated with nevoid basal cell carcinoma syndrome which usually has a more rapid growth. The aim of the study is to report the experience of our service on diagnosis and treatment of KOT.

Materials and methods

Twenty-five cases of KOT were diagnosed between the years of 1989 and 2006. Demographic data was collected as well as diagnose and treatment.

Results

Fifty-six percent were female with a mean age of 33 years old. Seventy percent occurred in mandibula and all received surgical treatment, associate or not with adjuvant therapy, such as cryotherapy and Carnoy's solution. Recidive was observed in 48% of cases with a mean period of time of 18 months.

Conclusion

Our data analysis showed the importance of previous diagnosis before enucleation procedure and long-term follow-up for recurrence early detection. Recurrence incidence is more frequent on first year after diagnosis.

Clinical significance

KOT is a benign tumor with local aggressive behavior and therefore its treatment must consider the high index of recidive. Reports of protocol treatment should raise new discussion to decrease recurrence rates.

How to cite this article

Schussel JL, Stramandinoli RT, Dissenha JL, Avila LFC, Sassi LM. Retrospective Study of 25 Cases of Keratocystic Odontogenic Tumor: Epidemiology and Treatment. J Contemp Dent Pract 2011;12(2):100-103.


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  1. Om keratocystedr (Kolesteratomer) and kaeberne. Tandlaegebladet 1956;60:963-71.
  2. Pathology and genetics of head and neck tumours. Lyon: IARC Press. WHO classification of tumours series 2005.
  3. PTCH gene mutations in odontogenic keratocysts. J Dent Res 2000;79:1418-22.
  4. Human homolog of patched, a candidate gene for the basal cell nevus syndrome. Science 1996;272:1668-71.
  5. Conservative treatment protocol of odontogenic keratocyst: A preliminary study. J Oral Maxillofac Surg 2006;64:379-83.
  6. Origin and growth of cysts of the jaws. Ann R Coll Surg Engl 1967;40:306-36.
  7. Treatment of odontogenic keratocysts: A follow-up of 255 Chinese patients. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002;94:151-56.
  8. Odontogenic keratocysts: A clinical and histologic comparison of the parakeratin and orthokeratin variants. J Oral Maxillofac Surg 1992;50:22-26.
  9. Keratocystic odontogenic tumor: A retrospective study of 183 cases. J Oral Sci 2008;50:205-12.
  10. Marsupialization as a definitive treatment for the odontogenic keratocyst. J Oral Maxillofac Surg 200462651-55. discussion 655-56.
  11. Decompression and marsupialization as a treatment for the odontogenic keratocyst. Oral Maxillofac Surg Clin North Am 2003;15:415-27.
  12. Long-term follow-up on keratocysts treated according to a defined protocol. Int J Oral Maxillofac Surg 2001;30:14-25.
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