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VOLUME 14 , ISSUE 4 ( July-August, 2013 ) > List of Articles

RESEARCH ARTICLE

Utilization of Dental Pulp DNA as Diagnostic Molecular Marker for Fertility Detection in Men

Hossam A Eid, Tarek H Taha, Manea M Alahmari, Abdullah Awn S Alqarni, Abdulkarim Ali H Alshehri

Citation Information : Eid HA, Taha TH, Alahmari MM, Alqarni AA, Alshehri AA. Utilization of Dental Pulp DNA as Diagnostic Molecular Marker for Fertility Detection in Men. J Contemp Dent Pract 2013; 14 (4):590-594.

DOI: 10.5005/jp-journals-10024-1369

Published Online: 01-08-2013

Copyright Statement:  Copyright © 2013; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Aim of study

The aim of this study was to use DNA material extracted from human teeth pulp for detection of fertility status of men.

Materials and methods

Twenty extracted premolar teeth of systemic disease free male Saudi individuals (45 years average age) were collected; eight of them were infertile while others were fertile and were used as control group. This information was concealed until the PCR analysis was performed. The results of recorded patient information was matched with the results of the DNA analysis.

Results

Results showed that the gene (sY83) an important gene of AZFa region in Y chromosome is important for male fertility. It was later evident that the infertile patients suffered from azoospermia, and that information is completely matched with our results.

Conclusion

Using DNA extracted from dental pulp can be used successfully in determining fertility status of human which may help in an accurate personal identification specially in extreme circumstances.

How to cite this article

Eid HA, Taha TH, Alahmari MM, Alqarni AAS, Alshehri AAH. Utilization of Dental Pulp DNA as Diagnostic Molecular Marker for Fertility Detection in Men. J Contemp Dent Pract 2013;14(4):590-594.


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