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VOLUME 19 , ISSUE 2 ( February, 2018 ) > List of Articles


Angiogenesis and Fibrogenesis in Oral Submucous Fibrosis: A Viewpoint

Supriya M Kheur, Sheetal S Choudhari, Deepak G Kulkarni, Sangeeta Patankar

Citation Information : Kheur SM, Choudhari SS, Kulkarni DG, Patankar S. Angiogenesis and Fibrogenesis in Oral Submucous Fibrosis: A Viewpoint. J Contemp Dent Pract 2018; 19 (2):242-245.

DOI: 10.5005/jp-journals-10024-2244

License: CC BY 3.0

Published Online: 01-04-2013

Copyright Statement:  Copyright © 2018; The Author(s).


Clinical significance

Understanding the association between angiogenesis and fibrogenesis can help in developing new therapeutic strategies for treatment of OSF.

How to cite this article

Choudhari SS, Kulkarni DG, Patankar S, Kheur SM, Sarode SC, Sarode GS, Patil S. Angiogenesis and Fibrogenesis in Oral Submucous Fibrosis: A Viewpoint. J Contemp Dent Pract 2018;19(2):242-245.

  1. Oral submucous fibrosis: its pathogenesis and management. Br Dent J 1986 Jun;160(12):429-434.
  2. Oral submucous fibrosis: review on etiology and pathogenesis. Oral Oncol 2006 Jul;42(6):561-568.
  3. Characterisation and quantification of mucosal vasculature in oral submucous fibrosis. Indian J Dent Res 2005 Jul-Sep;16(3):83-91.
  4. Immunohistochemical expression of CD34 for characterization and quantification of mucosal vasculature and its probable role in malignant transformation of atrophic epithelium in oral submucous fibrosis. Oral Oncol 2010 Jul;46(7):553-558.
  5. Early stage oral submucous fibrosis is characterized by increased vascularity as opposed to advanced stages. J Clin Diagn Res 2017 May;11(5):ZC92-ZC96.
  6. Morphometric analysis of the mucosal vasculature in oral submucous fibrosis and its comparison with oral squamous cell carcinoma. J Oral Sci 2014 Jun;56(2):173-178.
  7. Concomitant examination of inflammation and angiogenesis in the pathogenesis of primary moderate pterygium in a well-designed case-control study. Pak J Biol Sci 2013 Oct;16(19):1046-1050.
  8. Use of a fibrin-based system for enhancing angiogenesis and modulating inflammation in the treatment of hyperglycemic wounds. Biomaterials 2014 Feb;35(6):2001-2010.
  9. IL-32 promotes angiogenesis. J Immunol 2014 Jan;192(2):589-602.
  10. Interleukin-6 released by colon cancer-associated fibroblasts is critical for tumour angiogenesis: anti-interleukin-6 receptor antibody suppressed angiogenesis and inhibited tumour-stroma interaction. Br J Cancer 2014 Jan;110(2):469-478.
  11. The role of vascular endothelial growth factor in inflammatory processes. Postepy Hig Med Dosw (Online) 2014 Jan;68:57-65.
  12. Role of inflammatory mediators in angiogenesis. Curr Drug Targets Inflamm Allergy 2005 Feb;4(1):3-8.
  13. CCL2-dependent infiltrating macrophages promote angiogenesis in progressive liver fibrosis. Gut 2014 Dec;63(12):1960-1971.
  14. Cellular and molecular mechanisms in liver fibrogenesis. Arch Biochem Biophys 2014 Apr;548:20-37.
  15. Hypoxia: a link between fibrogenesis, angiogenesis, and carcinogenesis in liver disease. Semin Liver Dis 2010 Aug;30(3):258-270.
  16. Hypoxia, angiogenesis and liver fibrogenesis in the progression of chronic liver diseases. World J Gastroenterol 2010 Jan;16(3):281-288.
  17. Hypoxia and hypoxia inducible factors: diverse roles in liver diseases. Hepatology 2012 Feb;55(2):622-633.
  18. Angiogenesis in chronic liver disease and its complications. Liver Int 2011 Feb;31(2):146-162.
  19. Angiogenesis: a phenomenon which aggravates chronic liver disease progression. Hepatol Int 2013 Mar;7(1):4-12.
  20. Differential roles of angiogenesis in the induction of fibrogenesis and the resolution of fibrosis in liver. Biol Pharm Bull 2015 Jul;38(7):980-985.
  21. Hypoxia-induced increase in the production of extracellular matrix proteins in systemic sclerosis. Arthritis Rheum 2007 Dec;56(12):4203-4215.
  22. Mechanisms of hypoxic regulation of plasminogen activator inhibitor-1 gene expression in keloid fibroblasts. J Invest Dermatol 2003 Nov;121(5):1005-1012.
  23. Hypoxia and hypoxia signaling in tissue repair and fibrosis. Int Rev Cell Mol Biol 2012 Dec;296:139-185.
  24. Matrix stiffening in the formation of blood vessels. Adv Regen Biol 2014 Oct;1(1):25247.
  25. Endostatin, an angiogenesis inhibitor, ameliorates bleomycin-induced pulmonary fibrosis in rats. Respir Res 2013 May;14(1):56.
  26. Levistilide A inhibits angiogenesis in liver fibrosis via vascular endothelial growth factor signaling pathway. Exp Biol Med (Maywood) 2017 May;242(9):974-985.
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