Aim and objective: Peri-implantitis is a key concern for dental implants and the main common reason for implant failure. This investigation evaluated the risk factors and their implications on peri-implantitis. Materials and methods: A retrospective search of the patients’ clinical notes was performed to identify the documented cases of peri-implantitis. The inclusion criteria encompassed patients who were 18 years and older and were seen at the School of Dental Medicine, University of Nevada, Las Vegas, from January 2014 through September 2018. The search revealed that the number of peri-implantitis cases was 28, with an overall 45 implants. Data were collected and analyzed using the Chi-square test. Results: Total 28 patients presented with peri-implantitis. The distribution of males to females with peri-implantitis was 60.7 and 39.3%, respectively. The highest number of patients (21.4%) presenting with peri-implantitis fell within the age range of 65–69 years; 53.3% of peri-implantitis cases were in the maxillary arch. The predilection area for peri-implantitis was the mandibular first molar (24.4%). Periodontitis was the most significant cause (60.7%); respiratory diseases (42.9%) followed by hypertension (28.6%) were the most prevalent medical conditions in the studied population. Peri-implantitis occurred most frequently among Caucasians (62.7%), followed by Hispanics (29%). Conclusion: Within the limitations of the current evaluation, findings support previous claims that periodontitis remains the strongest predictor of peri-implantitis. A correlation may exist between peri-implantitis and the location of the implant and respiratory disease. Clinical significance: The implant location, the presence of periodontitis, and respiratory diseases are considered to be risk factors for peri-implantitis.
Dodson TB. Predictors of dental implant survival. J Mass Dent Soc 2006;54:34–38.
Anitua E, Orive G, Aguirre JJ, et al. 5-year clinical experience with BTI dental implants: risk factors for implant failure. J Clin Peri 2008;35(8):724–732. DOI: 10.1111/j.1600-051X.2008.01248.x.
Jemt T, Olsson M, Renouard F, et al. Early implant failures related to individual surgeons: an analysis covering 11,074 operations performed during 28 years. Clin Implant Dent and Rel Res 2016;18(5):861–872. DOI: 10.1111/cid.12379.
Rakic M, Galindo-Moreno P, Monje A, et al. How frequent does peri-implantitis occur? A systematic review and meta-analysis. Clin Oral invest 2018;22(4):1805–1816. DOI: 10.1007/s00784-017-2276-y.
Lindhe J, Meyle J. Peri-implant disease: consensus report of the sixth European workshop on periodontology. J Clin Peri 2008;35:282–285. DOI: 10.1111/j.1600-051X.2008.01283.x.
Mombelli A, Müller N, Cionca N. The epidemiology of peri-implantitis. Clin Oral Implants Res 2012;23:67–76. DOI: 10.1111/j.1600-0501.2012.02541.x.
Renvert S, Aghazadeh A, Hallstrom H, et al. Factors related to peri-implantitis—a retrospective study. Clin Oral Implants Res 2014;25(4):522–529. DOI: 10.1111/clr.12208.
Sanz I, Garcia-Gargallo M, Herrera D, et al. Surgical protocols for early implant placement in post-extraction sockets: a systematic review. Clin Oral Implants Res 2012;23:67–79. DOI: 10.1111/j.1600-0501.2011.02339.x.
Lee CT, Huang YW, Zhu L, et al. Prevalence of peri-implantitis and peri-implant mucositis: systematic review and meta-analysis. J Dent 2017;62:1–12. DOI: 10.1016/j.jdent.2017.04.011.
Renvert S, Quirynen M. Risk indicators for peri-implantitis. A narrative review. Clin Oral Implants Res 2015;26:15–44. DOI: 10.1111/clr.12636.
Schwarz F, Becker K, Rahn S, et al. Real-time PCR analysis of fungal organisms and bacterial species at peri-implantitis sites. Int J Implant Dent 2015;1(1):9. DOI: 10.1186/s40729-015-0010-6.
Serino G, Ström C. Peri-implantitis in partially edentulous patients: association with inadequate plaque control. Clin Oral Implants Res 2009;20(2):169–174. DOI: 10.1111/j.1600-0501.2008.01627.x.
Mombelli A, Marxer M, Gaberthüel T, et al. The microbiota of osseointegrated implants in patients with a history of periodontal disease. J Clin Perio 1995;22(2):124–130. DOI: 10.1111/j.1600-051X.1995.tb00123.x.
Seki K, Nakabayashi S, Tanabe N, et al. Correlations between clinical parameters in implant maintenance patients: Analysis among healthy and history-of-periodontitis groups. Int J Implant Dent 2017;3(1):45. DOI: 10.1186/s40729-017-0108-0.
Renvert S, Persson GR. Periodontitis as a potential risk factor for peri-implantitis. J Clin Perio 2009;36:9–14. DOI: 10.1111/j.1600-051X.2009.01416.x.
Costa FO, Takenaka-Martinez S, Cota LM, et al. Peri-implant disease in subjects with and without preventive maintenance: a 5-year follow-up. J Clin Perio 2012;39(2):173–181. DOI: 10.1111/j.1600-051X.2011.01819.x.
Monje A, Aranda L, Diaz KT, et al. Impact of maintenance therapy for the prevention of peri-implant diseases: a systematic review and meta-analysis. J Dent Res 2016;95(4):372–379. DOI: 10.1177/0022034515622432.
Pjetursson BE, Thoma D, Jung R, et al. A systematic review of the survival and complication rates of implant-supported fixed dental prostheses (FDPs) after a mean observation period of at least 5 years. Clin Oral Implants Res 2012;23:22–38. DOI: 10.1111/j.1600-0501.2012.02546.x.
Atieh M, Alsabeeha N, Faggion C, et al. The frequency of peri-implant diseases: a systematic review and meta-analysis. J of Perio 2012;84:1586–1598. DOI: 10.1902/jop.2012.120592.
Sturgill R. Prevalence and clinical characteristics of teeth extracted with a diagnosis of cracked tooth: a retrospective study. VCU Scholars Compass 2017. 1–450.
Levin L, Ofec R, Grossmann Y, et al. Periodontal disease as a risk for dental implant failure over time: a long-term historical cohort study. J Clin Perio 2011;38(8):732–737. DOI: 10.1111/j.1600-051X.2011.01745.x.
Karoussis IK, Salvi GE, Heitz-Mayfield LJ, et al. Long-term implant prognosis in patients with and without a history of chronic periodontitis: a 10-year prospective cohort study of the ITI dental implant system. Clin Oral Implants Res 2003;14(3):329–339. DOI: 10.1034/j.1600-0501.000.00934.x.
Schou S, Holmstrup P, Worthington HV, et al. Outcome of implant therapy in patients with previous tooth loss due to periodontitis. Clin Oral Implants Res 2006;17(S2):104–123. DOI: 10.1111/j.1600-0501.2006.01347.x.
Arunyanak SP, Sophon N, Tangsathian T, et al. The effect of factors related to periodontal status toward peri-implantitis. Clin Oral Implants Res 2019;30(8):791–799. DOI: 10.1111/clr.13461.
Marcantonio C, Nicoli LG, Marcantonio Junior E, et al. Prevalence and possible risk factors of peri-implantitis: a concept review. J Contemp Dent Pract 2015;16(9):750–757. DOI: 10.5005/jp-journals- 10024-1752.
Naujokat H, Kunzendorf B, Wiltfang J. Dental implants and diabetes mellitus—a systematic review. Inter J Implant Dent 2016;2(1):5. DOI: 10.1186/s40729-016-0038-2.
Noguchi M, Tsuno H, Ishizaka R, et al. Primary peri-implant oral intra-epithelial neoplasia/carcinoma in situ: a case report considering risk factors for carcinogenesis. Inter J Implant Dent 2017;3(1):47. DOI: 10.1186/s40729-017-0109-z.
Laverty DP, Addison O, Wubie BA, et al. Outcomes of implant-based oral rehabilitation in head and neck oncology patients—a retrospective evaluation of a large, single regional service cohort. Inter J Implant Dent 2019;5(1):8. DOI: 10.1186/s40729-019-0161-y.
Vervaeke S, Collaert B, Cosyn J, et al. A multifactorial analysis to identify predictors of implant failure and peri-implant bone loss. Clin Implant Dent Relat Res 2015;17:e298–e307. DOI: 10.1111/cid.12149.
Mengel R, Heim T, Thöne-Mühling M. Mucositis, peri-implantitis, and survival and success rates of oxide-coated implants in patients treated for periodontitis 3-to 6-year results of a case-series study. Int J Impl Dentis 2017;3(1):48. DOI: 10.1186/s40729-017-0110-6.
Mameno T, Wada M, Onodera Y, et al. Longitudinal study on risk indicators for peri-implantitis using survival-time analysis. J Prosthodon Res 2019;63(2):216–220. DOI: 10.1016/j.jpor.2018.12.002.