The Journal of Contemporary Dental Practice

Register      Login

SEARCH WITHIN CONTENT

FIND ARTICLE

Volume / Issue

Online First

Archive
Volume  25 (2024)
Volume  24 (2023)
Volume  23 (2022)
Volume  22 (2021)
Volume  21 (2020)
Volume  20 (2019)
Volume  19 (2018)
Volume  18 (2017)
Volume  17 (2016)
Volume  16 (2015)
Volume  15 (2014)
Volume  14 (2013)
Volume  13 (2012)
Volume  12 (2011)
Volume  11 (2010)
Volume  10 (2009)
Volume  9 (2008)
Volume  8 (2007)
Volume  7 (2006)
Volume  6 (2005)
Volume  5 (2004)
Volume  4 (2003)
Volume  3 (2002)
Volume  2 (2001)
Volume  1 (1999)
Related articles

VOLUME 21 , ISSUE 9 ( September, 2020 ) > List of Articles

ORIGINAL RESEARCH

A Comparative Study of Platelet-rich Fibrin (PRF) and Titanium-prepared Platelet-rich Fibrin (T-PRF) in Management of Endo-perio Lesions

Mohammed A Razi, Ankit Mahajan, Salil Mehra, Tulika Rani Roy, Puja Kumari

Keywords : Endo-perio lesions, Platelet-rich fibrin, Titanium-prepared platelet-rich fibrin

Citation Information : Razi MA, Mahajan A, Mehra S, Roy TR, Kumari P. A Comparative Study of Platelet-rich Fibrin (PRF) and Titanium-prepared Platelet-rich Fibrin (T-PRF) in Management of Endo-perio Lesions. J Contemp Dent Pract 2020; 21 (9):997-1001.

DOI: 10.5005/jp-journals-10024-2865

License: CC BY-NC 4.0

Published Online: 20-01-2021

Copyright Statement:  Copyright © 2020; The Author(s).


Abstract

Aim: The aim of the study was to compare the platelet-rich fibrin (PRF) and titanium-prepared platelet-rich fibrin (T-PRF) in the management of endo-perio lesions. Materials and methods: This study was conducted with 140 patients who are affected by endo-perio lesions, and the patients were divided into two groups. In group I, patients were treated with PRF, and in group II, patients were treated with T-PRF. Endodontic treatment was done in all cases, following a standardized aseptic method. Probing pocket and relative attachment level were recorded after 3 months and 6 months in both groups. Results: After 3 months, the mean change of probing pocket depth (PPD) was 68% in group I and 33.41% in group II. The intergroup distinction was not significant (p > 0.05), whereas the intragroup evaluation was significant (p < 0.05). The mean change after 6 months was 42.59% in group I and 43.90% in group II. The difference was not significant (p > 0.05). After 3 months, the mean% change of relative attachment level (RAL) was 31.20% in group I and 31.60% in group II. The intergroup distinction was not significant (p > 0.05), whereas the intragroup evaluation established a considerable discrepancy (p < 0.05). The mean change after 6 months was 40.82% in group I and 42.12% in group II. Conclusion: Both PRF and T-PRF were effective in inducing a reduction in pocket depth and useful in gaining attachment level. Clinical significance: With the use of PRF and T-PRF, the complex case of endo-perio lesions can be efficiently managed.

HTML PDF Share
  1. Sharma A, Pradeep AR. Treatment of 3-wall intrabony defects in patients with chronic periodontitis with autologous platelet-rich fibrin: a randomized controlled clinical trial. J Periodontol 2011;82(12):1705–1712. DOI: 10.1902/jop.2011.110075.
  2. Thorat M, Pradeep AR, Pallavi B. Clinical effect of autologous platelet-rich fibrin in the treatment of intra-bony defects: a controlled clinical trial. J Clin Periodontol 2011;38(10):925–932. DOI: 10.1111/j.1600-051X.2011.01760.x.
  3. Aroca S, Keglevich T, Barbieri B, et al. Clinical evaluation of a modified coronally advanced flap alone or in combination with a platelet-rich fibrin membrane for the treatment of adjacent multiple gingival recessions: a 6-month study. J Periodontol 2009;80(2):244–252. DOI: 10.1902/jop.2009.080253.
  4. Vishwanath V, Rao HM, Keshava Prasad BS, et al. Successful endodontic management of endo-perio lesions with different treatment modalities: case series. SRM J Res Dent Sci 2019;10(2):105–109. DOI: 10.4103/srmjrds.srmjrds_16_19.
  5. Tunalı M, Özdemir H, Küçükodacı Z, et al. In vivo evaluation of titanium-prepared platelet-rich fibrin (T-PRF): a new platelet concentrate. Br J Oral Maxillofac Surg 2012;51(5):438–443. DOI: 10.1016/j.bjoms.2012.08.003.
  6. Chatterjee A, Pradeep AR, Garg V, et al. Treatment of periodontal intrabony defects using autologous platelet-rich fibrin and titanium platelet rich fibrin: a randomized, clinical, comparative study. J Investig Clint Dent 2017;8:e12231. DOI: 10.1111/jicd.12231.
  7. Eren G, Tervahartiala T, Sorsa T, et al. Cytokine (interleukin-1beta) and MMP levels in gingival crevicular fluid after use of platelet-rich fibrin or connective tissue graft in the treatment of localized gingival recessions. J Periodontal Res 2016;51:481–488. DOI: 10.1111/jre.12325.
  8. Dohan Ehrenfest DM, Del Corso M, Diss A, et al. Three-dimensional architecture and cell composition of a Choukroun's platelet-rich fibrin clot and membrane. J Periodontol 2010;81:546–555. DOI: 10.1902/jop.2009.090531.
  9. Dambhare A, Bhongade ML, Dhadse PV, et al. A randomized controlled clinical study of autologous platelet rich fibrin (PRF) in combination with HA and beta-TCP or HA and beta-TCP alone for treatment of furcation defects. J Hard Tissue Biol 2019;28(2):185–190. DOI: 10.2485/jhtb.28.185.
  10. Goyal L, Gupta N, Gupta ND. Autologous platelet-rich derivatives along with alloplastic bone substitute in the management of complex perio-endo cases. J Indian Soc Periodontol 2020;24(2):182–185. DOI: 10.4103/jisp.jisp_81_19.
  11. Patel GK, Deepika PC, Sisodia N, et al. Platelet rich fibrin in management of complex endoperio cases. Kathmandu Univ Med J (KUMJ) 2017;15(57):102–105.
  12. Singh PK, Kumari A. Prevalence and distribution of different types of bone defects in chronic periodontitis in Bagalkot subjects: a clinical study. Int J Sci Stud 2017;5(3):284–289.
  13. Indurkar MS, Verma R. Evaluation of the prevalence and distribution of bone defects associated with chronic periodontitis using cone-beam computed tomography: a radiographic study. J Interdiscip Dent 2016;6(3):104–109. DOI: 10.4103/2229-5194.201647.
  14. Sachdeva S, Phadnaik MB, Mania A, et al. Prevalence and distribution of bone defects associated with moderate and severe periodontitis patients. Clinical Epidemiology and Global Health 2020; 1–6. [In press].
  15. Najim U, Norderyd O. Prevalence of intrabony defects in a swedish adult population. A radiographic epidemiological study. Acta Odontologica Scandinavica 2017;17(2):123–129. DOI: 10.1080/00016357.2016.1265665.
  16. Wu SK, Yeh HC, Chan CP. The prevalence and distribution of bone defects in patients with moderate to advanced periodontitis. Chang Gung Med J 2001;24(7):423–430.
  17. Mitra DK, Potdar PN, Prithyani SS, et al. Comparative study using autologous platelet-rich fibrin and titanium prepared platelet-rich fibrin in the treatment of infrabony defects: an in vitro and in vivo study. J Indian Soc Periodontol 2019;23(6):554–561. DOI: 10.4103/jisp.jisp_562_18.
  18. Shashikumar P, Nisha S. Autologous platelet concentrate as a potential regenerative biomaterial in the treatment of endo-perio lesion. Indian J Oral Health Res 2016;2:106–109. DOI: 10.4103/2393-8692.196148.
  19. Yu-Chao C, Kuo-Chin W, Jiing-Huei Z. Clinical application of platelet-rich fibrin as the sole grafting material in periodontal intrabony defects. J Dent Sci 2011;6:181–188. DOI: 10.1016/j.jds.2011. 05.010.
  20. Maniyar N, Sarode GS, Sarode SC, et al. Platelet-rich fibrin: a “wonder material” in advanced surgical dentistry. Med J DY Patil Vidyapeeth 2018;11:287–290. DOI: 10.4103/MJDRDYPU.MJDRDYPU_204_17.
  21. Del Fabbro M, Ceresoli V, Lolato A, et al. Effect of platelet concentrate on quality of life after periradicular surgery: a randomized clinical study. J Endod 2012;38(6):733–739. DOI: 10.1016/j.joen.2012. 02.022.
  22. Monga P, Grover R, Mahajan P, et al. A comparative clinical study to evaluate the healing of large periapical lesions using platelet-rich fibrin and hydroxyapatite. Endodontology 2016;28:27–31. DOI: 10.4103/0970-7212.184336.
  23. Jayalakshmi KB, Agarwal S, Singh MP, et al. Platelet-rich fibrin with β-tricalcium phosphate-a novel approach for bone augmentation in chronic periapical lesion: a case report. Case Rep Dent 2012;2012:902858. DOI: 10.1155/2012/902858.
  24. Thanikasalam M, Ahamed S, Narayana SS, et al. Evaluation of healing after periapical surgery using platelet-rich fibrin and nanocrystalline hydroxyapatite with collagen in combination with platelet-rich fibrin. Endodontology 2018;30:25–31.
  25. Deenadayalan E, Kumar A, Tewari RK, et al. Management of large periapical lesion with the combination of second generation platelet extract and hydroxyapatite bone graft: a report of three cases. J Clin Diagn Res 2015;9(1):ZD24–ZD27. DOI: 10.7860/JCDR/2015/10885.5482.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.