Aim: The present study was conducted to analyze the clinical and histopathological cases of odontogenic tumors (OTs).
Materials and methods: The present 10-year retrospective study comprised of 104 OTs. Parameters such as name, age, gender, clinical features, location, extension, etc were noted. H and E stained slides were carefully assessed by an oral pathologist and were classified according to the latest WHO classification of head and neck tumors.
Results: Out of 104 OTs, the most common was ameloblastoma constituting 45 cases, KCOT (28), odontoma (17), odontogenic myxoma (4), Calcifying epithelial odontogenic tumor (CEOT) (5), cementoblastoma (3) and calcifying cystic odontogenic tumor (2). The p value found to be 0.01 (significant). Common OTs was ameloblastoma (25 males and 20 males), KCOT (12 males and 16 females), odontoma (10 males and 7 females), odontogenic myxoma (3 males and 1 female), CEOT (3 males and 2 females), cementoblastoma (2 males and 1 female) and calcifying cystic odontogenic tumor (1 male and 1 female). Ameloblastoma, KCOT, and odontoma were predominantly seen in the age group 21-30 years, CEOT and cementoblastoma in age group 31-40 years. The difference was significant (P < 0.05). Common clinical features in OTs were facial disfigurement (65), swelling (78) and pain (55). The difference was non significant (P > 0.05). The average size of ameloblastoma was 6.8cm, KCOT was 4.2 cm, odontoma was 3.9 cm, odontogenic myxoma was 2.7 cm, CEOT was 5.5 cm, cementoblastoma was 3.8 cm and Calcifying cystic odontogenic tumour (COC) was 3.6 cm. The difference was non-significant (p > 0.05).
Conclusion: Mandible exhibited more OTs as compared to the maxilla. The most common lesion was ameloblastoma, KCOT, and odontomas. We observed male predominance.
Clinical significance: The study helps in assessing the occurrence of the odontogenic tumor. This is useful for identification and clinical management.
Luo HY, Li TJ. Odontogenic tumors: a study of 1,309 cases in Chinese population. Oral Oncology 2009;45:706-711.
Kim SG, Jang HS. Ameloblastoma: A clinical, radiographic and histopathologic analysis of 71 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2001;91:649-653.
Adebayo, E. T.; Ajike, S. O. andAdekeye, E. O. A review of 318 odontogenic tumors in Kaduna, Nigeria. J. Oral Maxillofac. Surg. 2005;63(6):811-819.
Tawfik, M. A. and Zyada, M. M. Odontogenic tumors in Dakahlia, Egypt: analysis of 82 cases. Oral Surg. Oral Med. Oral Pathol Oral Radiol Endod 2010;109(2): 67-73.
Santos JN, Pereira Pinto L, Figueredo CRLV, Souza LB. Odontogenic tumors: analysis of 127 cases. Pesqui Odont Bras 2001;15:308-313.
Ledesma-Montes C, Mosqueda-Taylor A, Carlos-Bregni R, de Leon ER, Palma-Guzman JM, Perez-Valencia C, et al. Ameloblastomas: a regional Latin-American multicentric study. Oral Dis 2007;13(3):303-307.
Olaitan AA, Adeola DS, Adekeye EO. Ameloblastoma: clinical features and management of 315 cases from Kaduna, Nigeria. J Craniomaxillofac Surg 1993;21:351-355.
Vidya Kadashetty et al. Odontogenic tumors- A retrospective study of 102 cases. IJOCR 2014;2(1):7-11.
Francisco et al. Clinicopathological and demographic characteristics of ameloblastomas in a population from Bahia, Brazil. Rev. Odontoscienc. 2010;25(3):250-255.
Atoalah Habibi et al. Keratocystic Odontogenic tumors- A 10 years retrospective study of 83 cases in an Iranina population J Oral scie. 2007;(49)3:229-235.
Osterne RL, Brito RG, Alves AP, Cavalcante RB, Sousa FB.Odontogenic tumors: a 5-year retrospective study in a Brazilian population and analysis of 3406 cases reported in the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011;111(4):474-481.
Avelar RL, Antunes AA, Santos TS, Andrade ES, Dourado E. Odontogenic tumors: clinical and pathology study of 238 cases. Braz J Otorhinolaryngol. 2008;74(5):668-673.
Seo-Young An, Chang-Hyeon An, Karp-Shik Choi. Odontoma: a retrospective study of 73 cases. Imaging Science in Dentistry 2012;42:77-81.
Jing W, Xuan M, Lin Y, Wu L, Liu L, Zheng X, et al. Odontogenictumours: a retrospective study of 1642 cases in a Chinese population. Int J Oral Maxillofac Surg 2007; 36(1):20- 25.
Olgac V, Koseoglu BG, Aksakalli N. Odontogenictumours in Istanbul: 527 cases. Br J Oral Maxillofac Surg 2006; 44(5):386- 388.
Grasieli de Oliveira Ramos et al. Odontogenic tumors: a 14-year retrospective study in Santa Catarina, Brazil. Braz Oral Res. 2014;28(1):1-6.
Sriram G, Shetty RP. Odontogenic tumors: a study of 250 cases in an Indian teaching hospital. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008;105:14-21.
El-Gehani, R.; Orafi, M.; Elarbi, M. andSubhashraj, K. Benign tumours of orofacial region at Benghazi, Libya: a study of 405 cases. J. Craniomaxillofac. Surg., 2009;37(7): 370-375.
Saghravanian N, Jafarzadeh H, Bashardoost N, Pahlavan N, Shirinbak I. Odontogenic tumors in an Iranian population: a 30-year evaluation. J Oral Sci 2010;52(3):391-396.
Guerrisi M, Piloni MJ, Keszler A. Odontogenic tumors in children and adolescents. A 15-year retrospective study in Argentina. Med Oral Patol Oral Cir Bucal 2007;12(3): 180-185.
Bruktawit et al. Odontogenic tumors in Ethiopia: eight years retrospective study. BMC Oral Health 2017;17: 54.
da Costa D-O-P, Mauricio A-S, de Faria P-A-S, da Silva L-E, Mosqueda-Taylor A, Lourenco S-Q-C. Odontogenic tumors: a retrospective study of four Brazilian diagnostic pathology centers. Med Oral Patol Oral Cir Bucal 2012;17:389- 394.
Buchner A, Merrell PW, Carpenter WM. Relative frequency of 23. Peripheral odontogenic tumors: a study of 45 new cases and comparison with studies from the literature. J Oral Pathol Med 2006;35:385-391.
Okada, H.; Yamamoto, H. and Tilakaratne W. M. Odontogenic tumors in Sri Lanka: analysis of 226 cases. J. Oral Maxillofac. Surg 2007; 65(5):875-882.