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VOLUME 19 , ISSUE 8 ( 2018 ) > List of Articles


Effectiveness of Roselle Effervescent Tablets as Traditional Medicinal Plants in preventing Growth of Candida albicans Colonies and Streptococcus mutans

Edy Machmud

Keywords : Candida albicans, Roselle effervescent tablets, Streptococcus mutans.

Citation Information : Machmud E. Effectiveness of Roselle Effervescent Tablets as Traditional Medicinal Plants in preventing Growth of Candida albicans Colonies and Streptococcus mutans. J Contemp Dent Pract 2018; 19 (8):925-928.

DOI: 10.5005/jp-journals-10024-2358

License: CC BY-NC 3.0

Published Online: 01-08-2018

Copyright Statement:  Copyright © 2018; The Author(s).


Aim: To analyze the effectiveness of roselle effervescent tablets inhibiting the growth of Streptococcus mutans and Candida albicans colonies on acrylic resin plate. Materials and methods: A total of 90 plates of acrylic resin with S. mutans and C. albicans suspensions were divided into three groups of immersion: The first group was soaked in a solution of roselle effervescent tablets 10%, the second group soaked in solution of sodium perborate effervescent tablets, and the third group soaked in a solution of pure effervescent tablets each with an interval of 5, 10, and 15 minutes. The number of colonies of S. mutans and C. albicans was calculated before and after immersion to determine the effectiveness of effervescent tablets. Data were analyzed using t-test and one-way analysis of variance (ANOVA). Results: The roselle effervescent tablets 10% showed a significant difference before and after immersion, thus inhibiting the growth of S. mutans and C. albicans colonies (p < 0.05). Roselle effervescent tablets 10% in immersion time 5, 10, and 15 minutes did not show any significant difference. The effectiveness of roselle effervescent tablets 10% did not show any significant differences with sodium perborate effervescent tablets. Conclusion: Roselle effervescent tablets are effective in preventing S. mutans and C. albicans colonies like effectiveness with sodium perborate effervescent tablets. Clinical significance: Roselle effervescent tablets 10% are effective in inhibiting the S. mutans and C. albicans colonies with immersion time of 5 minutes and have the same effectiveness with sodium perborate effervescent tablets.

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  1. Voon HC, Baht R, Rusul G. Flower extracts and their essential oils as potential antimicrobial agents for food uses and pharmaceutical applications. Compr Rev Food Sci Food Saf 2012;11(1).
  2. Pacome OB, Bernard DN, Sekau D, Joseph DA, David NJ, Mangomoke K, Hilaire KT. Phytochemical and antioxidant activity of Roselle (Hibiscus Sabdariffa L.) petal extracts. Res J Pharm Biol Chem Sci 2014;5(2):1453.
  3. Alaga TO, Edema MO, Atayase AO, Bankole MO. Phytochemical and in vitro anti-bacterial properties of hibiscus sabdariffa L (Roselle) juice. J Med Plant Res 2014;8(6):339-344.
  4. Ratnasari A, Widajati W, Hendrijantini N. The effect of rosella flower infusion in inhibiting Candida albicans colonization on acrylic resin. J Prosthod 2013;4(1):22-26.
  5. Rathee M, Hooda A, Ghalaut P. Denture hygiene in geriatric persons. J Geriatr Gerontol 2010;6(1):8-15.
  6. Andrade IM, Cruz PC, Silva CH, Souza RF, Paranhos HF, Candido RC, Marin JM, de Souza-Gugelmin MC. Effervescent tablets and ultrasonic devices against Candida and mutans streptococci in denture biofilms. Gerodontology 2011 Dec;28(4): 264-270.
  7. Ribeiro DG, Pavarina AC, Dovigo LN, Machado AL, Giampaolo ET, Verdant CE. Prevalence of Candida spp. associated with bacteria species on complete dentures. Gerodontology 2012 Sep;29(3):203-208.
  8. de Souza RF, Paranhos HF, da Silva CH, Abu-Naba'a L, Fedorowicz Z, Gurgan CA. Interventions for complete denture cleaning in adults. Cochrane Database Syst Rev 2009 Oct 7;(4):CD007395.
  9. Piranhas HF, Silva CH, Souza RF, Crush PC, Freitas KM, Peracini A. Effects of mechanical and chemical method on denture biofilm accumulation. J Oral Rehabil 2007 Aug;34(8): 606-612.
  10. Sataphaty SR, Patra M, Patnaik M. Process and variation effervescent formulation review. Innovat Int J Med Pharm Sci 2016;1(1).
  11. Vieria AP, Senna PM, Silva WJ, Cury AA. Long-term efficacy of denture cleansers in preventing Candida spp. biofilm recolonization on liner surface. Braz Oral Res 2010;24(3):342-348.
  12. Porcini A, Davi LR, Ribeiro NQ, Souza RF, Silva CH, Paranhos HO. Effect of denture cleansers on physical properties of heatpolymerized acrylic resin. J Prosthodont Res 2010 Apr;54(2): 78-83.
  13. Ganesh S, Gujiari AK, Kumar BS. Comparative study to access the effectiveness of various disinfectants on two microorganisms and the effect of same on flexural strength of acrylic denture base resin an in vitro study. J Int Oral Health 2013;5(3):55-62.
  14. Yildirim-Bicer AZ, Peker I, Akca G, Celik I. In vitro antifungal evaluation of seven different disinfectants on acrylic resins. Biomed Res Int 2014;2014:519098.
  15. Lee RE. Key facts about a unique dosage form effervescent tablet. Amerinlab Technologies; 2004.
  16. Shinawi L. The effect of various denture cleansers on the colour stability of different denture base resins. Int J Pharm Res 2017;6(2):238-246.
  17. Desrosiers M, Myntti M, James G. Methods for removing bacterial biofilms in vitro study using clinical chronic rhino sinusitis specimens. Am J Rhinol 2007;21:527-532.
  18. Ntrouka V, Hoogenkamp M, Zaura E, Van der Weijden F. The effect of chemotherapeutic agents on titanium-adherent biofilms. Clin Oral Implants Res 2011 Nov;22(11):1227-1234.
  19. Izumi S, Ryu M, Ueda T, Ishihara K, Sakurai K. Evaluation of application possibility of water containing organic acids for chemical denture cleaning for older adults. Geriatr Gerontol Int 2016;16(3):300-306.
  20. Faot F, Cavalcanti YW, Bertolini MM, Pinto LR, Silva WJ, Cury AA. Efficacy of citric acid denture cleanser on the Candida albicans biofilm formed on polymethyl methacrylate: effects on residual biofilm and recolonization process. BMC Oral Health 2014 Jun 23;14(77):1-7.
  21. Sayago-ayerdi SG, Arranz S, Serrano J, Goni I. Dietary fiber content and associated antioxidant compounds in Roselle flower (Hibiscus sabdariffa L.) beverage. J Agric Food Chemo 2007 Sep 19;55(19):7886-7890.
  22. Nurkhasanah, Yuwono T, Nurani LH, Rizki MI, Kraisintu K. The development of chitosan nanoparticles from hibiscus sabdariffa calyx extract from Indonesia and Thailand. Int J Pharm Sci Res 2015;6(5):1855-1861.
  23. Grotewold E. The science of flavonoids. New York: Springer Publishers; 2006. pp. 1-280.
  24. Jawetz EM. Review of medical microbiology. 16th ed. San Fransisco: Longo Medical Pub; 1986. pp. 143-148, 297-299.
  25. Goyal P, Anggarwal BK. A study on combinatorial effects of various flavonoids for their antibacterial potential against clinically significant bacterial species. Hacettepe J Biol Chem 2010;38(4):255-258.
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