The Journal of Contemporary Dental Practice

Register      Login



Volume / Issue

Online First

Related articles

VOLUME 19 , ISSUE 8 ( 2018 ) > List of Articles


Effects of using Antifungal Gel on Retentive Bond Strength of Two Forms of Denture Adhesives: An in vitro Study

Abdulelah M BinMahfooz, Osama A Qutub, Ghadeer I Basunbul, Khaled K El-Din Amin, Mosa M Altassan, Sahar MN Bukhary

Keywords : Antifungal denture adhesives, Antifungal miconazole nitrate, Denture adhesive retention, Snug denture cushion, Zinc-free PoliGrip cream.

Citation Information : BinMahfooz AM, Qutub OA, Basunbul GI, Amin KK, Altassan MM, Bukhary SM. Effects of using Antifungal Gel on Retentive Bond Strength of Two Forms of Denture Adhesives: An in vitro Study. J Contemp Dent Pract 2018; 19 (8):943-948.

DOI: 10.5005/jp-journals-10024-2362

License: CC BY-NC 3.0

Published Online: 01-03-2018

Copyright Statement:  Copyright © 2018; The Author(s).


Aim: The purpose of this in vitro study is to compare the bond strength to denture acrylics efficacy of miconazole gel against two denture adhesives with improved retentive properties (zincfree PoliGrip cream and Snug denture soft cushion). Materials and methods: Eight heat-cured acrylic samples were prepared measuring 0.7 cm × 1.4 cm flat tested surface. The two well-adapted tested surfaces were matched and fixed to Universal Testing Machine clamp. Vertical separating load was applied at a rate of 1 mm/min to yield the maximum load before denture adhesive failure occurs. These measurements were used to express the retention bond strength when improved denture adhesive material was applied alone in comparison with miconazole nitrate gel. Results were analyzed using one-way analysis of variance (ANOVA) statistical analysis at p-value of < 0.05. Results: There was a statistically significant reduction in the mean tensile strength when the antifungal gel was opposed by the zinc-free PoliGrip cream. However, such a significant difference was not evident when the Snug denture cushion was opposed by the miconazole gel. Conclusion: The addition of antifungal gel to denture adhesives reduces retentive bond strength of denture adhesives to denture acrylics. However, if an antifungal gel has to be used, then a denture adhesive cushion soft plastic liner may provide a better retentive option than denture adhesive cream. Clinical significance: The incorporation of an antifungal agent into denture adhesives is required in many denture patients to suppress fugal growth and eliminate the undesirable health effects associated with such infections.

PDF Share
  1. Mañes JF, Selva EJ, De-Barutell A, Bouazza K. Comparison of the retention strengths of three complete denture adhesives: an in vivo study. Med Oral Patol Oral Cir Bucal 2011 Jan;16(1):e132-e136.
  2. Tallgren A. The continuing reduction of the residual alveolar ridges in complete denture wearers: a mixed-longitudinal study covering 25 years. J Prosthet Dent 1972 Feb;27(2):120-132.
  3. Duqum I, Powers KA, Cooper L, Felton D. Denture adhesive use in complete dentures: clinical recommendations and review of the literature. Gen Dent 2012 Nov-Dec;60(6):467-477, quiz pp. 478-479.
  4. Han JM, Hong G, Dilinuer M, Lin H, Zheng G, Wang XZ, Sasaki K. The adhesive strength and initial viscosity of denture adhesives. Acta Odontol Scand 2014 Nov;72(8):839-845.
  5. Kamran MF, Chaudhary MA, Qamar K. Clinical comparison of retention strengths of two denture adhesives. Pak Oral Dent J 2016 Jul-Sep;36(3):507-511.
  6. Hang F, Barber AH. Nano-mechanical properties of individual mineralized collagen fibrils from bone tissue. J R Soc Interface 2011 Apr;8(57):500-505.
  7. Shekar S, Mittal S, Kalra N. Denture adhesives—a literature review. Dentistry 2016 Feb;6(3):364.
  8. Kumar MS, Thombare RU. A comparative analysis of the effect of various denture adhesives available in market on the retentive ability of the maxillary denture: an in vivo study. J Indian Prosthodont Soc 2011 Jun;11(2):82-88.
  9. Nicolas E, Veyrune Jl, Lassauzay C. A six-month assessment of oral health-related quality of life of complete denture wearers using denture adhesive: a pilot study. J Prosthodont 2010 Aug;19(6):443-448.
  10. Mason KL, Erb Downward JR, Mason KD, Falkowski NR, Eaton KA, Kao JY, Young VB, Huffnagle GB. Candida albicans and bacterial microbiota interactions in the cecum during recolonization following broad-spectrum antibiotic therapy. Infect Immun 2012 Oct;80(10):3371-3380.
  11. Gendreau L, Loewy ZG. Epidemiology and etiology of denture stomatitis. J Prosthodont 2011 Jun;20(4):251-260.
  12. Makihira S, Nikawa H, Satonobu SV, Jin C, Hamada T. Growth of Candida species on commercial denture adhesives in vitro. Int J Prosthodont 2001 Jan-Feb;14(1):48-52.
  13. Garaicoa JL, Fischer CL, Bates AM, Holloway J, Avila-Ortiz G, Guthmiller JM, Johnson GK, Stanford C, Brogden KA. Promise of combining antifungal agents in denture adhesives to fight Candida species infections. J Prosthodont 2016 Nov.
  14. Cartagena AF, Esmerino LA, Polak-Junior R, Parreiras SO, Michél MD, Farago PV, Campanha NH. New denture adhesive containing miconazole nitrate polymeric microparticles: antifungal, adhesive force and toxicity properties. Dent Mater 2017 Feb;33(2):e53-e61.
  15. Hasegawa S, Sekita T, Hayakawa I. Effect of denture adhesive on stability of complete dentures and the masticatory function. J Med Dent Sci 2003 Dec;50(4):239-247.
  16. Adisman IK. The use of denture adhesive as an aid to denture treatment. J Prosthet Dent 1989 Dec;62(6):711-715.
  17. Kumar PR, Shajahan PA, Mathew J, Koruthu A, Aravind P, Ahammed MF. Denture adhesives in prosthodontics: an overview. J Int Oral Health 2015;7(Suppl 1):93-95.
  18. Pradies G, Sanz I, Evans O, Martinez F, Sanz M. Clinical study comparing the efficacy of two denture adhesives in complete denture patients. Int J Prosthodont 2009 Jul-Aug;22(4): 361-367.
  19. Salman YM, Ibrahim IK. Effect of denture adhesives on the retention of maxillary complete denture. J Baghdad Coll Dent 2005;17(1):30-35.
  20. Park J-B, Prodduturi S, Morott J, Kulkarni VI, Jacob MR, Khan SI, Stodghill SP, Repka MA. Development of an antifungal denture adhesive film for oral candidiasis utilizing hot melt extrusion technology. Expert Opin Drug Deliv 2015 Jan;12(1):1-13.
  21. Liguori G, Di Onofrio V, Lucariello A, Gallé F, Signoriello G, Colella G, D'Amora M, Rossano F. Oral candidiasis: a comparison between conventional methods and multiplex polymerase chain reaction for species identification. Oral Microbiol Immunol 2009 Feb;24(1):76-78.
  22. Llabot JM, Palma SD, Manzo RH, Allemandi DA. Design of novel antifungal mucoadhesive films: part II. Formulation and in vitro biopharmaceutical evaluation. Int J Pharm 2007 May;336(2):263-268.
  23. Sampaio-Maia B, Figueiral MH, Sousa-Rodrigues P, Fernandes MH, Scully C. The effect of denture adhesives on Candida albicans growth in vitro. Gerodontology 2012 Jun;29(2):e348-e356.
  24. Scher EA, Ritchie GM, Flowers DJ. Antimycotic denture adhesive in treatment of denture stomatitis. J Prosthet Dent 1978 Dec;40(6):622-627.
  25. Nations SP, Boyer PJ, Love LA, Burritt MF, Butz JA, Wolfe GI, Hynan LS, Resich J, Trivedi JR. Denture cream an unusual source of excess zinc, leading to hypocupremia and neurologic disease. Neurology 2008 Aug;71(9):639-643.
  26. Chowdhry P, Phukela SS, Patil R, Yadav H. A study to evaluate the retentive ability of different denture adhesive materials: an in vitro study. J Indian Prosthodont Soc 2010 Sep;10(3): 176-181.
  27. An Y, Li D, Roohpour N, Gautrot JE, Barber AH. Failure mechanisms in denture adhesives. Dent Mater 2016 May;32(5):615-623.
  28. Snug denture cushion specifications. Denture adhesive guide. Scotland G74 5PE, UK. East Kilbride: Mentholatum Co. Ltd; Available from: snug-denture-cushions/.
  29. Panagiotouni E, Pissiotis A, Kapari D, Kaloyannides A. Retentive ability of various denture adhesive materials: an in vitro study. J Prosthet Dent 1995 Jun;73(6):578-585.
  30. Guo X, Deng F, Li L, Prud'homme RK. Synthesis of biocompatible polymeric hydrogels with tunable adhesion to both hydrophobic and hydrophilic surfaces. Biomacromolecules 2008 Jun;9(6):1637-1642.
  31. Dadarlat VM, Post CB. Adhesive-cohesive model for protein compressibility: an alternative perspective on stability. Proc Natl Acad Sci U S A 2003 Dec;100(25):14778-14783.
  32. Marshall SJ, Bayne SC, Baier R, Tomsia AP, Marshall GW. A review of adhesion science. Dent Mater 2010 Feb;26(2): e11-e16.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.