Citation Information :
Abdollahi A, Jalalian E. Effectiveness of Two Desensitizer Materials, Potassium Nitrate and Fluoride Varnish in Relieving Hypersensitivity After Crown Preparation. J Contemp Dent Pract 2019; 20 (4):489-493.
Aim: The aim of this clinical investigation was to compare the efficacy of fluoride varnish and potassium nitrate on the reduction of hypersensitivity of prepared teeth both pre and post cementation.
Materials and methods: In this randomized clinical trial, patients who needed at least three single crowns fixed partial prosthesis were included. Two desensitizing agents including fluoride varnish and potassium nitrate were used in this study and compared to the control group (sterile saline). In each patient, each prepared tooth was randomly assigned to one group. The desensitizing agent was applied on prepared teeth immediately after tooth preparation. The sensitivity of the teeth was measured by means of an air sensitivity test based on the visual analog scale at five different time points: baseline (2 hours after preparation), 7 days after preparation, before cementation, after cementation and one-week post cementation. Data were analyzed by Kruskal–Wallis and Friedman tests with a significant level of 0.05.
Results: Overall 300 vital abutment teeth needed full crown coverage in 100 patients were included. Both desensitizers’ agents decreased the sensitivity of vital abutment teeth compared to the control group at every time intervals except at baseline (p = 0.089). There was no significant difference between fluoride varnish and potassium nitrate in the reduction of pre-cementation sensitivity while one week after cementation, sensitivity was more relieved by potassium nitrate compared to fluoride varnish (p = 0.023).
Conclusion: The application of both desensitizers is effective in sensitivity reduction of vital abutment teeth. Potassium nitrate, however, is more eligible one week after cementation compared to fluoride varnish.
Clinical significance: Both potassium nitrate and fluoride varnish are capable of desensitizing prepared tooth for the fixed partial denture.
Consensus-based recommendations for the diagnosis and management of dentin hypersensitivity. J Can Dent Assoc 2003;69(4):221-226.
Salian, S, Thakur S, Kulkarni S, et al. A randomized controlled clinical study evaluating the efficacy of two desensitizing dentifrices. J Clin Dent 2010;21(3):82-87.
Tammaro, S, Wennstrom JL, Bergenholtz G. Root-dentin sensitivity following non-surgical periodontal treatment. J Clin Periodontol 2000;27(9):690-697.
West, N, Seong J, Davies M. Dentine hypersensitivity. Monogr Oral Sci 2014;25108-122.
Camps, J, About I, Gouirand S, et al. Dentin permeability and eugenol diffusion after full crown preparation. Am J Dent 2003;16(2):112-116.
Pihlaja, J, Napankangas R, Raustia A. Early complications and shortterm failures of zirconia single crowns and partial fixed dental prostheses. J Prosthet Dent 2014;112(4):778-783.
Jackson, CR, Skidmore AE, Rice RT. Pulpal evaluation of teeth restored with fixed prostheses. J Prosthet Dent 1992;67(3):323-325.
Morad, G, Behnia H, Motamedian SR, Shahab S, Gholamin P, Khosraviani K, et al. Thickness of labial alveolar bone overlying healthy maxillary and mandibular anterior teeth. J Craniofac Surg 2014;25(6):1985-1991.
Behnia, H, Motamedian SR, Kiani MT, et al. Accuracy and reliability of cone beam computed tomographic measurements of the bone labial and palatal to the maxillary anterior teeth. Int J Oral Maxillofac Implants 2015;30(6):1249-1255.
Safari S, Mahdian A, Motamedian SR. Applications of stem cells in orthodontics and dentofacial orthopedics: Current trends and future perspectives. World J Stem Cells 2018;10(6):66-77.
Khojasteh, A, Motamedian SR, Sharifzadeh N, et al. The influence of initial alveolar ridge defect morphology on the outcome of implants in augmented atrophic posterior mandible: an exploratory retrospective study. Clin Oral Implants Res 2017;28(10): e208-e217.
Khodadadi E, Mohammadpour M, Motamedian SR, et al. Failure Rate of Pediatric Dental Treatment under General Anesthesia. Dent J (Basel) 2018;6(3):E25.
Stern MA, Brudvik JS, Frank RP. Clinical evaluation of removable partial denture rest seat adaptation. J Prosthet Dent 1985;53(5): 658-662.
Pashley DH. Dentin permeability, dentin sensitivity, and treatment through tubule occlusion. J Endod 1986;12(10):465-474.
Kerns, DG, Scheidt MJ, Pashley DH, et al. Dentinal tubule occlusion and root hypersensitivity. J Periodontol 1991;62(7):421-428.
Peacock JM, Orchardson R. Effects of potassium ions on action potential conduction in A- and C-fibers of rat spinal nerves. J Dent Res 1995;74(2):634-641.
Orchardson R, Gillam DG. The efficacy of potassium salts as agents for treating dentin hypersensitivity. J Orofac Pain 2000;14(1):9-19.
Jacobsen PL, Bruce G. Clinical dentin hypersensitivity: understanding the causes and prescribing a treatment. J Contemp Dent Pract 2001;2(1):1-12.
Shetty R, Bhat AN, Mehta D, et al. Effect of a Calcium Phosphate Desensitizer on Pre- and Postcementation Sensitivity of Teeth Prepared for Full-Coverage Restorations: A Randomized, Placebo- Controlled Clinical Study. Int J Prosthodont 2017;30(1):38-42.
Nagata T, Ishida H, Shinohara H, et al. Clinical evaluation of a potassium nitrate dentifrice for the treatment of dentinal hypersensitivity. J Clin Periodontol 1994;21(3):217-221.
Pereira, JC, Martineli AC, Tung MS. Replica of human dentin treated with different desensitizing agents: a methodological SEM study in vitro. Braz Dent J 2002;13(2):75-85.
Tzanova, S, Ivanova Z, Velinova S. Clinical evaluation of dentinal hypersensitivity treatment with 5% potassium nitrate dentifrice. Folia Med (Plovdiv) 2005;47(2):65-69.
Sheykhzade M, Berg Nyborg NC. Mechanism of CGRP-induced relaxation in rat intramural coronary arteries. Br J Pharmacol 2001;132(6):1235-1246.
Merika K, Heftit Arthur F, Preshaw PM. Comparison of two topical treatments for dentine sensitivity. Eur J Prosthodont Restor Dent 2006;14(1):38-41.
Chu CH, Lo E. Uses of sodium fluoride varnish in dental practice. Ann R Australas Coll Dent Surg 2008;1958-1961.
Karim, BF, Gillam DG. The efficacy of strontium and potassium toothpastes in treating dentine hypersensitivity: a systematic review. Int J Dent 2013;2013573258.
Hooshmand B, Alavian SM, Kouhestani F, et al. Detection of Hepatitis C Virus RNA in Blood and Saliva of Transfusion-Dependent Thalassemia Patients Diagnosed with Hepatitis C. Contemp Clin Dent 2018;9(1): 5-9.
Tehranchi A, Motamedian SR, Saedi S, et al. Correlation between frontal sinus dimensions and cephalometric indices: A cross-sectional study. Eur J Dent 2017;11(1):64-70.
Eslamipour F, Motamedian SR, Bagheri F. Ibuprofen and Low-level Laser Therapy for Pain Control during Fixed Orthodontic Therapy: A Systematic Review of Randomized Controlled Trials and Metaanalysis. J Contemp Dent Pract 2017;18(6):527-533.
Shillingburg HT, Hobo S, Whitsett LD, et al. Fundamentals of Fixed Prosthodontics. Quintessence Publishing Co, Inc, IL. 2012;455-484.
Jalalian, E, Meraji N, Mirzaei M. A comparison of the efficacy of potassium nitrate and Gluma desensitizer in the reduction of hypersensitivity in teeth with full-crown preparations. J Contemp Dent Pract 2009;10(1):66-73.
Markowitz, K, Bilotto G, Kim S. Decreasing intradental nerve activity in the cat with potassium and divalent cations. Arch Oral Biol 1991;36(1):1-7.
Frechoso SC, Menendez M, Guisasola C, et al. Evaluation of the efficacy of two potassium nitrate bioadhesive gels (5% and 10%) in the treatment of dentine hypersensitivity. A randomised clinical trial. J Clin Periodontol 2003;30(4):315-320.
Brannstrom M, Nyborg H. Pulp reaction to fluoride solution applied to deep cavities: an experimental histological study. J Dent Res 1971;50(6):1548-1552.
Shen C, Autio-Gold J. Assessing fluoride concentration uniformity and fluoride release from three varnishes. J Am Dent Assoc 2002;133(2):176-182.
Ehrlich J, Hochman N, Gedalia I, et al. Residual fluoride concentrations and scanning electron microscopic examination of root surfaces of human teeth after topical application of fluoride in vivo. J Dent Res 1975;54(4):897-900.
Yadav, K, Sofat A, Gambhir RS, et al. Dentin hypersensitivity following tooth preparation: A clinical study in the spectrum of gender. J Nat Sci Biol Med 2014;5(1):21-24.