The Journal of Contemporary Dental Practice

Register      Login

SEARCH WITHIN CONTENT

FIND ARTICLE

Volume / Issue

Online First

Archive
Related articles

VOLUME 20 , ISSUE 11 ( November, 2019 ) > List of Articles

ORIGINAL RESEARCH

Remineralizing Effect of Casein Phosphopeptide–Amorphous Calcium Phosphate and Sodium Fluoride on Artificial Tooth Enamel Erosion: An In Vitro Study

Kevin Pirca, Gabriela Balbín-Sedano

Keywords : Keywords: Casein phosphopeptide–amorphous calcium phosphate, Dental erosion, Microroughness, Remineralization, Sodium fluoride

Citation Information : Pirca K, Balbín-Sedano G. Remineralizing Effect of Casein Phosphopeptide–Amorphous Calcium Phosphate and Sodium Fluoride on Artificial Tooth Enamel Erosion: An In Vitro Study. J Contemp Dent Pract 2019; 20 (11):1254-1259.

DOI: 10.5005/jp-journals-10024-2710

License: CC BY-NC 4.0

Published Online: 01-10-2019

Copyright Statement:  Copyright © 2019; The Author(s).


Abstract

Aim: To compare in vitro the remineralizing effect of toothpastes with casein phosphopeptide–amorphous calcium phosphate (FPC–FCA) and sodium fluoride on the artificial erosion of tooth enamel. Materials and methods: For the first phase of artificial erosion, group I was considered as the control group without treatment or erosion. For groups II and IV, the drink was used (Coca-Cola®), for groups III and V, the drink (Inca-Kola®), and the four groups were demineralized four times a day (every 3 hours for 2 minutes) for 5 days. In the treatment phase in groups II and III, brushing was performed with sodium fluoride paste (Colgate®), groups IV and V received brushing with FPC–FCA complex (MiPaste®), and for all groups, the same procedure was performed four times a day (every 3 hours for 5 minutes) for 90 days. At the end, the microroughness of the surfaces of all the groups was evaluated by means of a Rugosimeter (Mitutoyo). Results: It was evidenced that the group of sodium fluoride presented a microroughness of 2.79 μm being the group of least remineralization, but the FPC–FCA complex showed a microroughness of 1.96 μm; however, the control group presented a microroughness of 3.20 μm, and the groups sodium fluoride, FPC–FCA compared to the control group proved to be statistically significant with a p < 0.05. Conclusion: The remineralizing effect of FPC–FCA (MiPaste®) complex proved to be greater than sodium fluoride paste (Colgate®) under artificial enamel erosive conditions. Clinical importance: The results of this research serve as a basis for industries to generate products that have the potential for remineralization against various erosive beverages that are consumed daily.


HTML PDF Share
  1. Moezizadeh M, Alimi A. The effect of casein phosphopeptide–amorphous calcium phosphate paste and sodium fluoride mouthwash on the prevention of dentine erosion: an in vitro study. J Conserv Dent 2014;17(3):244–249. DOI: 10.4103/0972-0707.131787.
  2. Carvalho F, Brasil V, Silva Filho T, et al. Protective effect of calcium nanophosphate and CPP–ACP agents on enamel erosion. Braz Oral Res 2013;27(6):463–470. DOI: 10.1590/S1806-83242013000600004.
  3. Wegehaupt F, Tauböck T, Stillhard A, et al. Influence of extra- and intra oral application of CPP–ACP and fluoride on re-hardening of eroded enamel. Acta Odontol Scand 2012;70(3):177–183. DOI: 10.3109/00016357.2011.600713.
  4. Gupta R, Prakash V. CPP–ACP complex as a new adjunctive agent for remineralization: a review. Oral Health Prev Dent 2011;9(2):151–165.
  5. Gupta N, Mohan C, Nagpal R, et al. A review of casein phosphopeptide–amorphous calcium phosphate (CPP–ACP) and enamel remineralization. Compend Contin Educ Dent 2016;37(1): 36–39.
  6. Gurunathan D, Somasundaram S, Kumar S. Casein phosphopeptide-amorphous calcium phosphate: a remineralizing agent of enamel. Aust Dent J 2012;57(4):404–408. DOI: 10.1111/adj.12006.
  7. Ambarkova V, Goršeta K, Glavina D, et al. Učinak fluoridirane paste za zube na remineralizaciju cakline i mikrotvrdoću nakon demineralizacije in vitro. Acta Stomatol Croat 2011;45(3):159–165.
  8. Amaral C, Miranda M, Correa D, et al. Sodium fluoride and casein phosphopeptide–amorphous calcium phosphate cream plus sodium fluoride efficacy in preventing enamel erosion in a simulated oral environment study model. Indian J Dent Res 2014;25(4):464–469. DOI: 10.4103/0970-9290.142536.
  9. Agrawal N, Shashikiran N, Singla S, et al. Effect of remineralizing agents on surface microhardness of primary and permanent teeth after erosion. J Dent Child (Chic) 2014;81(3):117–121.
  10. Ranjitkar S, Kaidonis J, Richards L, et al. The effect of CPP–ACP on enamel wear under severe erosive conditions. Arch Oral Biol 2009;54(6):527–532. DOI: 10.1016/j.archoralbio.2009.03.006.
  11. Hegde M, Devadiga D, Jemsily P. Comparative evaluation of effect of acidic beverage on enamel surface pre-treated with various remineralizing agents: an in vitro study. J Conserv Dent 2012;15(4):351–356. DOI: 10.4103/0972-0707.101902.
  12. West N, Hughes J, Addy M. Erosion of dentine and enamel in vitro by dietary acids: the effect of temperature, acid character, concentration and exposure time. J Oral Rehabil 2000;27(10):875–880. DOI: 10.1046/j.1365-2842.2000.00583.x.
  13. Kitchens M, Owens B. Effect of carbonated beverages, coffee, sports and high energy drinks, and bottled water on the in vitro erosion characteristics of dental enamel. J Clin Pediatr Dent 2007;31(3): 153–159. DOI: 10.17796/jcpd.31.3.1157l653t8206100.
  14. Torres C, Chinelatti M, Gomes J, et al. Surface and subsurface erosion of primary enamel by acid beverages over time. Braz Dent J 2010;21(4):337–345. DOI: 10.1590/S0103-64402010000400009.
  15. Claudio P, Lombardini M, Marco C, et al. Impact of two toothpastes on repairing enamel erosion produced by a soft drink: an AFM in vitro study. J Dent 2010;38(20):868–874. DOI: 10.1016/j.jdent.2010.07.010.
  16. Manton D, Cai F, Yuan Y, et al. Effect of casein phosphopeptide amorphous calcium phosphate added to acidic beverages on enamel erosion in vitro. Aust Dent J 2010;55(3):275–279. DOI: 10.1111/j.1834-7819.2010.01234.x.
  17. Tocolini D, Dalledone M, Brancher J, et al. Evaluation of the erosive capacity of children's beverages on primary teeth enamel: an in vitro study. J Clin Exp Dent 2018;10(4):383–387. DOI: 10.4317/jced.54546.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.