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VOLUME 23 , ISSUE 5 ( May, 2022 ) > List of Articles

ORIGINAL RESEARCH

Evaluation of Remineralization Potential of Remin Pro Forte vs Remin Pro on White Spot Lesions: A Randomized Clinical Trial

Mennatallah Atef Aboulnaga, Mai Mamdouh Akah, Olfat El-Sayed Hassanein

Keywords : Caries regression, Color improvement, ICDAS II, Post-orthodontic treatment, Remineralization, Remin pro, Remin Pro Forte, VistaCam iX, White spot lesions

Citation Information : Aboulnaga MA, Akah MM, Hassanein OE. Evaluation of Remineralization Potential of Remin Pro Forte vs Remin Pro on White Spot Lesions: A Randomized Clinical Trial. J Contemp Dent Pract 2022; 23 (5):520-526.

DOI: 10.5005/jp-journals-10024-3335

License: CC BY-NC 4.0

Published Online: 10-08-2022

Copyright Statement:  Copyright © 2022; The Author(s).


Abstract

Aim: This study was conducted to evaluate the remineralization potential of Remin Pro Forte vs Remin Pro remineralizing agents on white spot lesions (WSLs) post-orthodontic treatment. Materials and methods: Twenty patients with post-orthodontic WSLs were divided into the following two equal groups based on treatment (n = 10): (1) A 3-month program of hydroxyapatite, fluoride, xylitol, ginger, curcuma-containing cream (Remin Pro Forte) as intervention group; (2) A 3-month cream regimen including hydroxyapatite and fluoride, xylitol (Remin Pro) as control group. The main outcomes including caries regression (assessed by ICDAS II), mineral content (assessed by VistaCam iX camera), and color of WSLs (assessed by digital image analysis by Adobe photoshop) were measured at the time of enrollment and 1, 2, and 3 months afterward. Mann–Whitney test used to compare between tested groups. The statistical significance was set at p <0.05. Results: Both Remin Pro Forte and Remin Pro elicited much better caries regression and significantly higher mineral content in WSLs over a 3-month period (p <0.05). However, the difference in mineral content of WSLs between groups did not reach statistical significance (p = 0.414). In both experimental groups, the appearance of WSLs improved significantly (p <0.05). Conclusion: Both Remin Pro Forte and Remin Pro were successful in reducing caries, increasing mineral content, and enhancing the appearance of demineralized enamel, indicating that both products could be suggested for post-orthodontic WSL management. Clinical significance: Natural herbal products could be employed as remineralizing agents and included into tooth preventive measures. It is a less harmful alternative to traditional chemical remineralization methods.


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  1. Huang GJ, Roloff–Chiang B, Mills BE, et al. Effectiveness of MI Paste Plus and PreviDent fluoride varnish for treatment of white spot lesions: a randomized controlled trial. Am J Orthod Dentofacial Orthop 2013;143(1):31–41. DOI: 10.1016/j.ajodo.2012.09.007.
  2. Hammad SM, El Banna M, El Zayat I, et al. Effect of resin infiltration on white spot lesions after debonding orthodontic brackets. Am J Dent 2012;25(1):3–8. PMID: 22558683.
  3. Nagarathana C, Sakunthala BK, Naveena Preethi P. An update on current remineralizing agent. OHDM 2015;14(4):183–187.
  4. Raksha B, Mithra H. An overview on remineralizing agents. IJAR 2016;6:333–335. DOI: 10.36106/ijar.
  5. Benjamin S, Roshni PS, Nainan MT. Seal that heals. World J Dent 2012;3(3):243–246. DOI: 10.5005/jp-journals-10015-1164.
  6. Heravi F, Ahrari F, Tanbakuchi B. Effectiveness of MI Paste Plus and Remin Pro on remineralization and color improvement of postorthodontic white spot lesions. Dent Res J 2018;15(2):95–103. PMID: 29576772.
  7. Park M, Bae J, Lee DS. Antibacterial activity of [10]‐gingerol and [12]‐gingerol isolated from ginger rhizome against periodontal bacteria. Phytother Res 2008;22(11):1446–1449. DOI: 10.1002/ptr.2473.
  8. Smullen J, Finney M, Storey DM, et al. Prevention of artificial dental plaque formation in vitro by plant extracts. J Appl Microbiol 2012;113(4):964–973. DOI: 10.1111/j.1365-2672.2012.05380.x.
  9. Bilgin G, Yanikoglu F, Tağtekin D. Remineralization potential of herbal mixtures: An in-situ study. Pripex-Inx J Res 2016;5(2):264–268. DOI: 10.36106/paripex.
  10. Basir L, Kalhori S, Javid AZ, et al. Anticaries activity of curcumin on decay process in human tooth enamel samples (in vitro study). J Natl Med Assoc 2018;110(5):486–490. DOI: 10.1016/j.jnma.2017.
  11. Kamh RA, Niazy MA, El-Yasaky MA. Clinical performance and remineralization potential of different biomimitic materials on white spot lesions. Al-Azhar Dental Journal for Girls. 2018;5(4):349–358. DOI: 10.21608/adjg.2018.20020.
  12. American Dental Association Council on Scientific Affairs. Fluoride toothpaste use for young children. J Am Dent Assoc 2014;145(2):190–191. DOI: 10.14219/jada.2013.47.
  13. Munjal D, Garg S, Dhindsa A, et al. Assessment of white spot lesions and in-vivo evaluation of the effect of CPP-ACP on white spot lesions in permanent molars of children. Journal of clinical and diagnostic research. JCDR 2016;10(5):ZC149–154. DOI: 10.7860/JCDR/2016/19458.7896.
  14. Bengel WM. Digital photography and the assessment of therapeutic results after bleaching procedures. J Esthet Restor Dent 2003;15(Suppl 1): S21–S32. DOI: 10.1111/j.1708-8240.2003.tb00315.x.
  15. Kamath U, Sheth H, Mullur D, et al. The effect of Remin Pro® on bleached enamel hardness: an in-vitro study. Indian D Dent Res 2013;24(6):690–693. DOI: 10.4103/0970-9290.127612.
  16. Willmot D. White spot lesions after orthodontic treatment. Semin Orthodont 2008;14(3):209–219. DOI: 10.1053/j.sodo.2008.03.006.
  17. Gugnani N, Pandit IK, Srivastava N, et al. International caries detection and assessment system (ICDAS): a new concept. Int J Clin Pediatr Dent 2011;4(2):93–100. DOI: 10.5005/jp-journals-10005-1089.
  18. Pretty IA. Caries detection and diagnosis: novel technologies. J Dent 2006;34(10):727–739. DOI: 10.1016/j.jdent.2006.06.001.
  19. Benson PE, Pender N, Higham SM, et al. Morphometric assessment of enamel demineralisation from photographs. J Dent 1998;26(8):669–677. DOI: 10.1016/s0300-5712(97)00051-1.
  20. Hoffmann T, Habil M. In vitro evaluation of two whitening regimens using color-analyzing methods. Quintessence Int 2010;41:145–156. PMID: 20165746.
  21. Knispel G. Factors affecting the process of color matching restorative materials to natural teeth. Quintessence Int 1991;22(7): 525–531. PMID: 1882045.
  22. Jablonski–Momeni A, Schipper HM, Rosen SM, et al. Performance of a fluorescence camera for detection of occlusal caries in vitro. Odontology 2011;99(1):55–61. DOI: 10.1007/s10266-010-0139-y.
  23. Sudarshan R, Vijayabala GS. Role of ginger in medicine and dentistry: an interesting review article. Southeast Asian J Case Rep Rev 2012;1(3):66–72.
  24. Ebrahimi M, Mehrabkhani M, Ahrari F, et al. The effects of three remineralizing agents on regression of white spot lesions in children: a two-week, single-blind, randomized clinical trial. J Clin Exp Dent 2017;9(5):e641–e648. DOI: 10.4317/jced.53582.
  25. Kiriştioğlu z, Yanikoglu F, Alkan E, TAĞTEKİN D. The effect of dental paste with herbal content on remineralization and the imaging with fluorescent technique in teeth with white spot lesion. Clin Exp Health Sci 2021;11(2):348–353. DOI: 10.33808/clinexphealthsci.848455.
  26. Esparza–Villalpando V, Fernandez–Hernandez E, Rosales–Berber M, et al. Clinical efficacy of two topical agents for the remineralization of enamel white spot lesions in primary teeth. Pediatr Dent 2021;43(2):95–101. PMID: 33892832.
  27. Youssef A, Farid M, Zayed M, et al. Improving oral health: a short-term split-mouth randomized clinical trial revealing the superiority of resin infiltration over remineralization of white spot lesions. Quintessence Int 2020;51(9) 696–709. DOI: 10.3290/j.qi.a45104.
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