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VOLUME 14 , ISSUE 5 ( September-October, 2013 ) > List of Articles

RESEARCH ARTICLE

An Investigation of Blood Hemogram and Estimation of Serum Iron and Protein Levels in Aggressive Periodontitis Patients: A Clinic Biochemical Study

R Vamshidhar Reddy, Dimple Arora, P Krishna Rao, Sagar Arjun Mapare, Venkat Ratna Nag, K Gowtham

Citation Information : Reddy RV, Arora D, Rao PK, Mapare SA, Nag VR, Gowtham K. An Investigation of Blood Hemogram and Estimation of Serum Iron and Protein Levels in Aggressive Periodontitis Patients: A Clinic Biochemical Study. J Contemp Dent Pract 2013; 14 (5):852-857.

DOI: 10.5005/jp-journals-10024-1415

Published Online: 01-10-2013

Copyright Statement:  Copyright © 2013; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Aim

The aim of this study is to investigate the blood hemogram and estimation of serum iron and proteins level in aggressive periodontitis patients.

Materials and methods

A total of 85 patients were selected and divided into two groups, 45 patients are with aggressive periodontitis and 40 patients are healthy. Periodontal parameters such as gingival inflammation oral hygiene index, Russell's periodontal index and radiograph were taken. Total 10 ml blood was collected and sent for estimation of blood hemogram protein estimation and serum electrophoresis.

Results

There was statistical significant difference observed in relation to gingival inflammation oral hygiene hemoglobin and total iron binding capacity level between both the groups.

Conclusion

It has been concluded that periodontitis does not induce anemia like state, as the hematological and biochemical parameters were almost equally affected in periodontally healthy and periodontally diseased individuals, but some parameters showed statistical significant difference between the both groups.

Clinical significance

In the present study, the clinical periodontal parameters, red blood cell parameters and serum iron and ferritin levels were compared among control and test groups. It was found that the values of gingival inflammation, oral hygiene and periodontal index, hemoglobulin level and total iron binding protein were statistically significant between the groups. However, the values of erythrocyte count, white blood cell count, serum iron and serum proteins, serum electrophoresis did not show any significant correlation.

How to cite this article

Rao PK, Reddy RV, Mapare SA, Nag VR, Gowtham K, Arora D. An Investigation of Blood Hemogram and Estimation of Serum Iron and Protein Levels in Aggressive Periodontitis Patients: A Clinic Biochemical Study. J Contemp Dent Pract 2013;14(5):852-857.


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  1. Influence of systemic diseases on the periodontium. In: Carranza, FA, Newmann MG, editors. Clinical periodontology. 8th ed. Philadelphia: WB Saunders; 1996. p. 185-205.
  2. Dental correlation nutritional disorders. In: Kaye D, Rose LF, editors. Internal medicine for dentistry. 2nd ed. St Louis: Mosby Company; 1990. p. 978-985.
  3. Acute-phase reactants in infections and inflammatory diseases. Periodontol 2000 2000;23:19-49.
  4. Elevation of systemic markers related to cardiovascular diseases in the peripheral blood of periodontitis patients. J Periodontol 2000;71(10):1528-1534.
  5. Anemia of chronic disease and chronic periodontitis: does periodontal therapy have effect on anemic status. J Periodontol 2011;82:388-394.
  6. Evaluation of systemic markers related to anemia of chronic disease in the peripheral blood of smokers and non-smokers with chronic periodontitis. Eur J Dent 2008;2:102-109.
  7. Systemic markers of inflammation in periodontitis. J Periodontol 2005;76(11Suppl):2106-2115.
  8. Dental correlation, anemia and deficiency states. In: Kaye D, Rose LF, editors. Internal medicine for dentistry. 2nd ed. St Louis: Mosby Company; 1990. p. 360-361.
  9. White blood cell count in generalized aggressive periodontitis after non-surgical therapy. J Clin Periodontol 2002;29(3):201-206.
  10. Evaluation of blood parameters in patients with chronic periodontitis for signs of anemia. J Periodontol 2010;81:1202-1206.
  11. Effect of periodontal therapy on hemoglobin and erythrocyte levels in chronic generalized periodontitis patients: An interventional study. J Indian Soc Periodontol 2009;13:6-11.
  12. Lower numbers of erythrocytes and lower levels of hemoglobin in periodontitis patients compared to control subjects. J Clin Periodontol 2001;28(10):93.
  13. Relationship between periodontitis and erythrocyte count. J Ind Soci Periodontol 2006;10:288-291.
  14. Periodontal and hematological characteristics associated with aggressive periodontitis, juvenile idiopathic arthritis, and rheumatoid arthritis. J Periodontol 2006;77(2):280-288.
  15. Anemia, a systemic cause of periodontal disease? J Periodontol. 1968;39:35-38.
  16. Anemia and periodontal disease–a correlative study. J Indian Dent Assoc 1971;43:67-78.
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