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VOLUME 16 , ISSUE 7 ( July, 2015 ) > List of Articles

REVIEW ARTICLE

Biomarkers of Orthodontic Tooth Movement in Gingival Crevicular Fluid: A Systematic Review

Adel M Alhadlaq

Citation Information : Alhadlaq AM. Biomarkers of Orthodontic Tooth Movement in Gingival Crevicular Fluid: A Systematic Review. J Contemp Dent Pract 2015; 16 (7):578-587.

DOI: 10.5005/jp-journals-10024-1725

Published Online: 01-01-2016

Copyright Statement:  Copyright © 2015; The Author(s).


Abstract

Background

The analysis of gingival crevicular fluid (GCF) may be an acceptable way to examine the ongoing biochemical processes associated with bone turnover during orthodontic tooth movement. If it is possible to biologically monitor and predict the outcome of orthodontic forces, then the management of appliances could be based on individual tissue responses, and the effectiveness of the treatment could be improved.

Methodology

A literature search was carried out in major databases, such as medline, EMBASE, cochrane library, web of science, google scholar and scopus for relevant studies. Publications in English between 2000 and 2014 which estimated GCF markers as indicators of orthodontic tooth movement were included.

Results

The list of biomarkers available to date was compiled and presented in table format. Each biomarker is discussed separately based on the available evidence.

Conclusion

Several sensitive GCF markers are available to detect the biomechanical changes occurring during orthodontic tooth movement. Further focused research might help to analyze the sensitivity and reliability of these indicators, which in turn can lead to the development of chairside tests to assess the outcome of orthodontic therapy.

How to cite this article

Alhadlaq AM. Biomarkers of Orthodontic Tooth Movement in Gingival Crevicular Fluid: A Systematic Review. J Contemp Dent Pract 2015;16(7):578-587.

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