The Journal of Contemporary Dental Practice

Register      Login

SEARCH WITHIN CONTENT

FIND ARTICLE

Volume / Issue

Online First

Archive
Related articles

VOLUME 17 , ISSUE 3 ( March, 2016 ) > List of Articles

RESEARCH ARTICLE

Higher Dental Caries Prevalence and Its Association with Dietary Habits and Physical Limitation in Epidermolysis Bullosa Patients: A Case Control Study

Rodrigo Antonio de Medeiros, Soraya Coelho Leal, Erica Negrini Lia, Rivadavio Amorim, Mateus Veppo dos Santos, Mayara Cundari de Araújo, Camila Abdanur da Fonseca

Citation Information : de Medeiros RA, Leal SC, Lia EN, Amorim R, Santos MV, de Araújo MC, da Fonseca CA. Higher Dental Caries Prevalence and Its Association with Dietary Habits and Physical Limitation in Epidermolysis Bullosa Patients: A Case Control Study. J Contemp Dent Pract 2016; 17 (3):211-216.

DOI: 10.5005/jp-journals-10024-1829

Published Online: 01-08-2016

Copyright Statement:  Copyright © 2016; The Author(s).


Abstract

Aim

Epidermolysis bullosa (EB) represents a highly rare subgroup of skin diseases that affects skin and mucous membrane. The aim of the present study was to assess caries prevalence and its associated factors in EB subjects. Salivary status was also assessed.

Materials and methods

Ten subjects with EB who were under supervision were selected (cases) and matched by age and gender with unaffected individuals (controls). Dental caries were recorded using the World Health Organization (WHO) criteria. Oral hygiene and dietary habits were investigated by clinical examination and questionnaires. Both nonstimulated and stimulated saliva were collected and salivary pH, buffering capacity and mouth opening were evaluated.

Results

The results showed that the median decay-missingfilled teeth was significantly higher (p = 0.0094) in EB cases 5 (3.9–20.3) than in controls 3 (2–3.25). The groups also differed when food consistency was analyzed. Individuals with EB have a higher intake of soft food. In addition, the median mouth-opening values from cases (0.84–2.84 cm) and controls (4.3–4.9 cm) have shown to be statistically different (p = 0.007). Considering the salivary parameters, none of them showed significant differences among groups.

Conclusion

Epidermolysis bullosa subjects present higher caries scores and might be related to their physical condition and dietary habits.

Clinical significance

There is a lack of information about oral status in EB subjects. Hence, our findings add useful information regarding the relationship between caries prevalence and associated risk factors in EB subjects.

How to cite this article

Leal SC, Lia EN, Amorim R, dos Santos MV, de Araújo MC, de Medeiros RA, da Fonseca CA. Higher Dental Caries Prevalence and its Association with Dietary Habits and Physical Limitation in Epidermolysis Bullosa Patients: A Case Control Study. J Contemp Dent Pract 2016;17(3):211-216.


PDF Share
  1. Multicentre consensus recommendations for skin care in inherited epidermolysis bullosa. Orphanet J Rare Dis 2014 May 20;9:76.
  2. Progress in epidermolysis bullosa: summary of a workshop in CILAD-2010. Int J Dermatol 2012 Jun;51(6):682-687.
  3. The classification of inherited epidermolysis bullosa (EB): report of the third International Consensus Meeting on Diagnosis and Classification of EB. J Am Acad Dermatol 2008 Jun;58(6):931-950.
  4. The prevalence of epidermolysis bullosa in Scotland. Br J Dermatol 1997 Apr;136(4):560-564.
  5. A consensus approach to wound care in epidermolysis bullosa. J Am Acad Dermatol 2012 Nov;67(5):904-917.
  6. Dental disease and caries related microflora in children with dystrophic epidermolysis bullosa. Pediatr Dent 2001 Sep-Oct;23(5):438-443.
  7. Sialolithiasis in the duct of submandibular gland: a case report in patient with epidermolysis bullosa. J Contemp Dent Pract 2013 Mar 1;14(2):339-344.
  8. Restrictions in oral functions caused by oral manifestations of epidermolysis bullosa. Eur J Dermatol 2011 May-Jun;21(3):405-409.
  9. Oral soft tissues in hereditary epidermolysis bullosa. Oral Surg Oral Med Oral Pathol 1991 Apr;71(4):440-446.
  10. Developmental defects of enamel in humans with hereditary epidermolysis bullosa. Arch Oral Biol 1993 Nov;38(11):945-955.
  11. Localized epidermolysis bullosa patient simplex with generalized enamel hypoplasia in a child. Pedatr Dermatol 2006 Mar-Apr;23(2):167-168.
  12. Salivary flow patterns and the health of hard and soft oral tissues. J Am Dent Assoc 2008 May;139Suppl: 18S-24S.
  13. Oral health surveys: basic methods. 4th ed. Geneva: World Health Organization; 1997.
  14. Saliva as a diagnostic tool for assessment of dental caries. Arch Orofac Sci 2006;1:57-59.
  15. Medication in elderly people: its influence on salivary pattern, signs and symptoms of dry mouth. Gerodontology 2010 Jun;27(2):129-133.
  16. Xerostomia and hyposalivation. Adv Dent Res 2000 Dec;14:48-56.
  17. Saliva composition and functions: a comprehensive review. J Contemp Dent Pract 2008 Mar 1;9(3):72-80.
  18. Saliva stimulation and caries prevention. Adv Dent Res 1994 Jul;8(2):239-245.
  19. Salivary function of persons with hereditary epidermolysis bullosa. Oral Surg Oral Med Oral Pathol 1991 May;71(5):553-559.
  20. Recent advances in dental research: bacteriology. Int Dent J 1962;12:443-464.
  21. Inherited epidermolysis bullosa: new diagnostic criteria and classification. Clin Dermatol 2012 Jan-Feb;30(1):70-77.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.