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VOLUME 17 , ISSUE 12 ( December, 2016 ) > List of Articles


Antibacterial Activity of Two Chemomechanical Caries Removal Gels on Carious Dentin of Primary Teeth: An in vitro Study

Hesham S Khalil, Ruchi Arora, Bhupendra Bhardwaj, Ghadah Abusalim, Amjad H Wyne

Citation Information : Khalil HS, Arora R, Bhardwaj B, Abusalim G, Wyne AH. Antibacterial Activity of Two Chemomechanical Caries Removal Gels on Carious Dentin of Primary Teeth: An in vitro Study. J Contemp Dent Pract 2016; 17 (12):1027-1032.

DOI: 10.5005/jp-journals-10024-1976

Published Online: 01-04-2017

Copyright Statement:  Copyright © 2016; The Author(s).



Chemomechanical caries removal (CMCR) is an effective method of caries removal especially for primary teeth as they cause less discomfort when compared with conventional caries removal. The most significant thing about caries removal is the elimination of cariogenic bacteria. This study compares the antibacterial activity of two CMCR gels.

Materials and methods

A total of 40 primary molar teeth with carious dentin were split along the long axis in a laboratory. Total viable count (TVC) was taken for the teeth before splitting as a measure of colony-forming units per milliliter (CFU/mL). Each half was treated with either Carisolv or Carie-Care CMCR gels. Clean dentin samples were evaluated for Streptococcus mutans (SM) and Lactobacillus acidophilus (LB) after removal of carious tissue using the caries removal gels using serial dilutions and incubating on specific agar plates.


The results showed significant reduction in mean TVC after use of both the CMCR gels. Both gels reduced the CFU/mL of SM and LB to a significant level (p < 0.05). However, there was no significant difference between the antibacterial activities of the two CMCR gels.


The CMCR gels (Carisolv and Carie-Care) significantly reduced the residual TVC as well as SM and LB in carious primary dentin. Both CMCR gels had a similar antibacterial activity on the carious dentin of primary teeth.

Clinical significance

The CMCR gels tested have a significant antibacterial activity and can be effectively used for elimination of caries-causing bacteria in primary teeth.

How to cite this article

Gulzar S, Arora R, Shah AH, Bhardwaj B, Abusalim G, Khalil HS, Wyne AH. Antibacterial Activity of Two Chemomechanical Caries Removal Gels on Carious Dentin of Primary Teeth: An in vitro Study. J Contemp Dent Pract 2016;17(12):1027-1032.

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