Aim: This study aims to examine the awareness, attitudes, and perceptions towards dental fluorosis in Hail, Saudi Arabia. Materials and methods: It was an epidemiological study with a descriptive cross-sectional design. Participants meeting the inclusion criteria were recruited from Hail, Saudi Arabia, through a convenient non-probability sampling strategy. The study planned to recruit at least 400 participants. However, (n = 419) was obtained during the 2 months of data collection. Data for the present study was collected using a validated questionnaire via Google form by disseminating it to the targeted population using non-probability snowball sampling through various social media platforms. The questionnaire comprised three parts including demographics (6 questions), a knowledge-related section comprised of (6 questions), and attitude relation portion (14 questions). Results: The majority of participants (n = 369, 88.1%) were willing to undergo treatment for dental improvement. Additionally, most respondents (n = 389, 92.8%) advocated for government participation in preventive programs and emphasized the importance of raising public awareness. Furthermore, a significant proportion (n = 401, 95.7%) expressed interest in launching mass public health campaigns to prevent dental fluorosis. Females showed significantly higher awareness levels. Conclusion: The study highlights significant sociodemographic influences on awareness and attitudes towards dental fluorosis. While age, nationality, and income showed no impact, gender and education were significant factors. Despite gaps in knowledge, there was strong support for preventive measures. Esthetic concerns were evident, with high rates of dental consultations and recognition of social stigma. Targeted interventions are needed to address knowledge gaps and promote preventive measures, considering sociodemographic differences and broader social implications. Clinical significance: The findings could be the cornerstone for promoting preventive measures and improving consultation behaviors, ultimately enhancing the overall management and prevention of dental fluorosis in the community.