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VOLUME 18 , ISSUE 6 ( June, 2017 ) > List of Articles

RESEARCH ARTICLE

Assessment of Levels of Glycosylated Hemoglobin in Patients with Periodontal Pathologies: A Comparative Study

Saurabh Wahi, Alok Tripathi, Shradha Wahi, Vikas D Mishra, Abhishek P Singh, Nikhil Sinha

Citation Information : Wahi S, Tripathi A, Wahi S, Mishra VD, Singh AP, Sinha N. Assessment of Levels of Glycosylated Hemoglobin in Patients with Periodontal Pathologies: A Comparative Study. J Contemp Dent Pract 2017; 18 (6):506-509.

DOI: 10.5005/jp-journals-10024-2074

Published Online: 01-10-2017

Copyright Statement:  Copyright © 2017; The Author(s).


Abstract

Introduction

One of the potential sources for the occurrence of various systemic pathologies, such as cardiovascular diseases, cerebrovascular diseases, and respiratory diseases is periodontitis. Testing of glycosylated hemoglobin (HbA) is a highly standardized procedure and is becoming increasingly popular these days due to its cost-effectiveness and ease of use. Literature quotes numerous studies associating the periodontal diseases with various hemoglobin markers in diabetic and nondiabetic patients. Hence, we planned the present study to assess the levels of HbA in patients with periodontitis among nondiabetic patients.

Materials and methods

For the present study, a total of 50 nondiabetic subjects who reported to the department with the chief complaint of periodontitis were included. Another set of 50 nondiabetic individuals were included in the present study of comparable age in whom no periodontitis was detected clinically. Clinical examination and radiographic evaluation was performed for the selection of the cases for the study group. The patients were sent to the laboratory after the clinical examination, for the testing of HbA. Testing of the hemoglobin A1c (HbA1c) levels of all the subjects and controls was performed and values were noted and evaluated.

Results

Nonsignificant results were obtained while comparing the mean HbA1c concentrations among the study group and the control group. Nonsignificant results were obtained while comparing the mean HbA1c levels among males and females. While comparing the mean HbA1c levels between the study group and the control group divided on the basis of body mass index, nonsignificant results were obtained.

Conclusion

In nondiabetic subjects, no significant correlation could be observed between periodontitis and HbA1c levels.

Clinical significance

The HbA1c cannot be used as a reliable maker for differentiation of patients with periodontal pathologies from patients free of periodontal pathologies.

How to cite this article

Wahi S, Tripathi A, Wahi S, Mishra VD, Singh AP, Sinha N. Assessment of Levels of Glycosylated Hemoglobin in Patients with Periodontal Pathologies: A Comparative Study. J Contemp Dent Pract 2017;18(6):506-509.


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  1. The effect of smoking on the response to periodontal therapy. J Clin Periodontol 1994 Feb;21(2):91-97.
  2. Cigar, pipe, and cigarette smoking as risk factors for periodontal disease and tooth loss. J Periodontol 2000 Dec;71(12):1874-1881.
  3. Risk indicators for periodontal disease in a racially diverse urban population. J Clin Periodontol 1996 Nov;23(11):982-988.
  4. A pilot study of glycosylated hemoglobin levels in periodontitis cases and healthy controls. J Periodontol 2009 Jul;80(7):1057-1061.
  5. Comparison of glycosylated hemoglobin levels in periodontitis patients and healthy controls: a pilot study in Indian population. Indian J Dent Res 2012 May-Jun;23(3):368-372.
  6. Personal risk factors for generalized periodontitis. J Clin Periodontol 1995 Feb;22(2):136-145.
  7. Effects of periodontal therapy on glycemic control and inflammatory markers. J Periodontol 2008 May;79(5):774-783.
  8. Association of periodontal parameters with metabolic level, systemic inflammatory markers in Type 2 diabetes patients. J Periodontol 2010 Mar;81(3):364-371.
  9. Quantifying the risk of infectious diseases for people with diabetes. Diabetes Care 2003 Feb;26(2):510-513.
  10. Ludwig's angina and ketoacidosis as a first manifestation of diabetes mellitus. Med Oral Patol Oral Cir Bucal 2010 Jul; 15(4):e624-e627.
  11. Comparison of glycosylated hemoglobin (HbA1C) levels in patients with chronic periodontitis and healthy controls. Dent Res J 2013 May-Jun;10(3):389-393.
  12. Relationship between periodontal status and levels of glycated hemoglobin. J Dent Res 2012 Feb;91(2):161-166.
  13. Comparison of glycosylated hemoglobin levels in severe periodontitis patients and healthy controls: a study in an Indian population. Quintessence Int 2013 Apr;44(4):319-325.
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