Citation Information :
Dhanya R, Adarsh V, Jalaluddin M, Rajasekaran U, Sudeep C. Comparative Evaluation of Neem Mouthwash on Plaque and Gingivitis: A Double-blind Crossover Study. J Contemp Dent Pract 2017; 18 (7):567-571.
The present study aimed at evaluating the impact of neemcontaining mouthwash on plaque and gingivitis.
Materials and methods
This randomized, double-blinded, crossover clinical trial included 40 participants aged 18 to 35 years with washout period of 1 week between the crossover phases. A total of 20 participants, each randomly allocated into groups I and II, wherein in the first phase, group I was provided with 0.2% chlorhexidine gluconate and group II with 2% neem mouthwash. After the scores were recorded, 1-week time period was given to the participants to carry over the effects of the mouthwashes and then the second phase of the test was performed. The participants were instructed to use the other mouthwash through the second test phase.
Results
There was a slight reduction of plaque level in the first phase as well as in the second phase. When comparison was made between the groups, no statistically significant difference was seen. Both the groups showed reduction in the gingival index (GI) scores in the first phase, and there was a statistically significant difference in both groups at baseline and after intervention (0.005 and 0.01 respectively). In the second phase, GI scores were reduced in both groups, but there was a statistically significant difference between the groups only at baseline scores (0.01).
Conclusion
In the present study, it has been concluded that neem mouthwash can be used as an alternative to chlorhexidine mouthwash based on the reduced scores in both the groups.
Clinical significance
Using neem mouthwash in maintaining oral hygiene might have a better impact in prevention as well as pervasiveness of oral diseases as it is cost-effective and easily available.
How to cite this article
Jalaluddin M, Rajasekaran UB, Paul S, Dhanya RS, Sudeep CB, Adarsh VJ. Comparative Evaluation of Neem Mouthwash on Plaque and Gingivitis: A Double-blind Crossover Study. J Contemp Dent Pract 2017;18(7):567-571.
Evaluation of antiplaque and antigingivitis effect of herbal mouthwash in treatment of plaque induced gingivitis: a randomized, clinical trial. J Indian Soc Periodontol 2014 Jan;18(1):48-52.
Chemical agents to prevent and regulate plaque development. Periodontology 2000 1995 Jun;8:87-107.
Antimicrobial activity of a poly-herbal extract against dental micro flora. Res J Pharm Biol Chem Sci 2011;2(2):533-539.
Role of phytotherapy in gingivitis: a review. J Pharmacol 2012;8:1-5.
To evaluate the efficacy of three commercially available herbal mouthwashes in treatment of chronic gingivitis: a comparative clinical study. Int J Dent Med Res 2014;1(4):42-46.
The antimicrobial effects of extracts of Azadirachta indica (Neem) and Salvadora persica (Arak) chewing sticks. Indian J Dent Res 1999 Jan-Mar;10(1):23-26.
An in vivo study of the plaque control efficacy of Persica: a commercially available herbal mouthwash containing extracts of Salvadora persica. Int Dent J 2004 Oct;54(5):279-283.
To evaluate the antigingivitis and antiplaque effect of an Azadirachta indica (Neem) mouthrinse on plaque induced gingivitis: a double-blind, randomized, controlled trial. J Indian Soc Periodontol 2011 Oct;15(4):398-401.
The inhibiting effect of aqueous Azadirachta indica (Neem) extract upon bacterial properties influencing in vitro plaque formation. J Dent Res 1996 Feb;75(2):816-822.
Herbal mouthwashes – a gift of nature. Int J Pharma Bio Sci 2012 Apr;3(2):46-52.
The distribution of plaque and gingivitis and the influence of toothbrushing hand in a group of South Wales 11-12 year-old children. J Clin Periodontol 1987 Nov;14(10):564-572.
Plaque growth and removal with daily toothbrushing. J Periodontol 1979 Dec;50(12):661-664.
Chemical plaque control-prevention for the masses. Periodontology 2000 1997 Oct;15:109-117.
A review of the literature on use of chlorhexidine in dentistry. J Am Dent Assoc 1986 Jun;112(6):863-869.
Efficacy of a mouthrinse based on leaves of the neem tree (Azadirachta indica) in the treatment of patients with chronic gingivitis: a double-blind, randomized, controlled trial. J Med Plants Res 2008 Nov;2(11):341-346.
Folklore therapeutic indigenous plants in periodontal disorders in India (Review, experimental and clinical approach). Int J Clin Pharmacol Ther Toxicol 1988 Apr;26(4):176-184.
Evaluation of antiplaque activity of Azadirachta indica leaf extract gel – a 6-week clinical study. J Ethnopharmacol 2004 Jan;90(1):99-103.
